USA NU578 EXAM 3 QUESTIONS AND
CORRECT ANSWERS. VERIFIED
2025/2026.
What is the moa for diuretics? - ANS Affects Maintenance of ecf volume and composition
What is the Path that urine takes through the nephron - ANS Glomerulus Prox convol
tube Loop of Henle: Descrnding limb Ascending limb DCT Collecting duct
What is the site of action for osmotic diuretics like
Mannitol? - ANS Proximal convoluted tubule
What is the Site of action for Thiazide diuretics like
HCTZ? - ANS Early distal convoluted tubule
What is the (site of action for Potassium sparing diuretics like
Spironolactone? - ANS Late distal convoluted tubule and collecting duct (distal nephron)
What is the sote of action for Loop diuretics like
Furosemide? - ANS Loop of Henle
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Loop diuretics cause drug toxicity due to increased Na+ excretion. - ANS Lithium excretion is
decreased with hyponatremia and causes lithium toxicity.
Nephron order of diuretic action - ANS Osmotics Loops
Thiazides K+ sparing
PCT (proximal convoluted tubule) - ANS High resorptive capacity. About 65% of filtered Na+
and Cl resorbed here. Urine is isotonic
Freely permeable to water - ANS Descending limb loop of Henle
Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by - ANS Distal nephron: late
DCT/CD
Causes transient deafness - ANS Furosemide
Only diuretic class that is ototoxic - ANS Loop diuretics (pg451)
Digoxin is potentiated with hypokalemia and ventricular dysrhythmias are greatly increased.
These diuretics promote K+ loss. - ANS Loop diuretics
Thiazide diuretics
Preferred drugs for mobilizing edema associated with mild to moderate failure -
ANS Thiazides
Diuretic Must be given parenterally. Only osmotic avail in US - ANS Mannitol
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
CORRECT ANSWERS. VERIFIED
2025/2026.
What is the moa for diuretics? - ANS Affects Maintenance of ecf volume and composition
What is the Path that urine takes through the nephron - ANS Glomerulus Prox convol
tube Loop of Henle: Descrnding limb Ascending limb DCT Collecting duct
What is the site of action for osmotic diuretics like
Mannitol? - ANS Proximal convoluted tubule
What is the Site of action for Thiazide diuretics like
HCTZ? - ANS Early distal convoluted tubule
What is the (site of action for Potassium sparing diuretics like
Spironolactone? - ANS Late distal convoluted tubule and collecting duct (distal nephron)
What is the sote of action for Loop diuretics like
Furosemide? - ANS Loop of Henle
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Loop diuretics cause drug toxicity due to increased Na+ excretion. - ANS Lithium excretion is
decreased with hyponatremia and causes lithium toxicity.
Nephron order of diuretic action - ANS Osmotics Loops
Thiazides K+ sparing
PCT (proximal convoluted tubule) - ANS High resorptive capacity. About 65% of filtered Na+
and Cl resorbed here. Urine is isotonic
Freely permeable to water - ANS Descending limb loop of Henle
Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by - ANS Distal nephron: late
DCT/CD
Causes transient deafness - ANS Furosemide
Only diuretic class that is ototoxic - ANS Loop diuretics (pg451)
Digoxin is potentiated with hypokalemia and ventricular dysrhythmias are greatly increased.
These diuretics promote K+ loss. - ANS Loop diuretics
Thiazide diuretics
Preferred drugs for mobilizing edema associated with mild to moderate failure -
ANS Thiazides
Diuretic Must be given parenterally. Only osmotic avail in US - ANS Mannitol
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.