CONTROLLED SUBSTANCES QUIZ, 578
U2. EXAM QUESTIONS AND CORRECT
ANSWERS. VERIFIED 2025/2026.
Abused prescription drug, second-most - ANS codeine
Act also known as the Controlled Substance Act (1970) - ANS Comprehensive Drug Abuse
Prevention and Control Act
actiq - ANS transmuscosal fentanyl only approved for breakthrough cancer pain in opioid
tolerant patients
addictive drugs all activate the brain's _________ - ANS dopamine reward circuit
after detox, an opioid addict can be rx'd ___________ to discourage renewed opioid abuse -
ANS naltrexone
AIDS patients use Dronabinol (marinol) - ANS for appetite stim
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,alvimopan - ANS used for tx of opioid-induced ileus
amphetamines are schedule - ANS II
amphetamines work primarily by promoting neuronal release of _________ & ___________,
and partly by blocking their reuptake - ANS norepinephrine; dopamine
amphetamines, most common adverse effects - ANS insomnia; weight loss
analgesics, most effective available - ANS opioids
avinza - ANS extended release morphine
barbiturate OD antidote? - ANS none, just supportive treatment
barbiturate OD produces same classic triad of symptoms (resp. depression, coma, pinpoint
pupils) as seen with - ANS opioid OD
barbiturate tolerant individuals are cross-tolerant to other CNS depressants (alcohol, benzos,
general anesthetics) but not with ________ - ANS opioids
behavior pattern characterized by continued use of a psychoactive substance despite physical,
psychologic, or social harm - ANS addiction
benzodiazepine principal indications are - ANS anxiety, insomnia, seizure disorders
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,benzodiazepines adverse effects - ANS daytime sedation; anterograde amnesia
benzodiazepines are classified as Schedule - ANS IV
benzodiazepines are primarily for which two anxiety d/o's - ANS panic disorder, GAD
benzodiazepines produce their actions by enhancing the effects of _____, the principal
inhibitory neurotransmitter in the CNS - ANS GABA
benzodiazepines-like controlled substace approved for long-term use in insomnia -
ANS eszopiclone (Lunesta)
black box warnings - ANS a component of REMS
bridging agents commonly abused - ANS methadone, tramadol, buprenorphine (suboxone)
buprenorphine formulations used in management of opioid addiction - ANS subutex or
suboxone SL
butorphanol (stadol) and nalbuphne (nubain) are contraind. In MI as they - ANS increase
cardiac work
butrans transdermal sites must be rotated. No site may be reused within ___ days - ANS 21
cancer pain - ANS frequently undertreated, able to be mitigated in 90% of cases with proper
dosing/drug therapy (consider adjuvants)
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, chronic opioid therapy candidates can be identified with - ANS ORT (opioid risk tool); SOAPP
(screener and opioid assessment for patients with pain); DIRE (diagnois, intractability, risk, and
efficacy score)
chronic opioid therapy fails - ANS 50-70% of the time
code of fed regulations, title 21, section 1306 governs - ANS issuance & filling of prescriptions
codeine by itself is a schedule ___ CS. In cough meds, it's often schedule ___ - ANS II, V
complement effects of opioids (in combo with, not in substitution of) - ANS adjuvant
analgesics
Comprehensive Drug Abuse Prevention and Control Act (1970) - ANS establishes regulations
for controlled substances for manufacturers, prescribers, pharmacists, and distributors
Comprehensive Drug Abuse Prevention and Control Act (1970) aka - ANS Controlled
Substance Act
controlled substance definition - ANS any drug whose use is controlled by fed gov.
controlled substance prescriptions require - ANS actual number & numerical value
cross-tolerance does not exist between opioid agonists and - ANS general CNS depressants
cross-tolerance exists among - ANS various opioid agonists
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
U2. EXAM QUESTIONS AND CORRECT
ANSWERS. VERIFIED 2025/2026.
Abused prescription drug, second-most - ANS codeine
Act also known as the Controlled Substance Act (1970) - ANS Comprehensive Drug Abuse
Prevention and Control Act
actiq - ANS transmuscosal fentanyl only approved for breakthrough cancer pain in opioid
tolerant patients
addictive drugs all activate the brain's _________ - ANS dopamine reward circuit
after detox, an opioid addict can be rx'd ___________ to discourage renewed opioid abuse -
ANS naltrexone
AIDS patients use Dronabinol (marinol) - ANS for appetite stim
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,alvimopan - ANS used for tx of opioid-induced ileus
amphetamines are schedule - ANS II
amphetamines work primarily by promoting neuronal release of _________ & ___________,
and partly by blocking their reuptake - ANS norepinephrine; dopamine
amphetamines, most common adverse effects - ANS insomnia; weight loss
analgesics, most effective available - ANS opioids
avinza - ANS extended release morphine
barbiturate OD antidote? - ANS none, just supportive treatment
barbiturate OD produces same classic triad of symptoms (resp. depression, coma, pinpoint
pupils) as seen with - ANS opioid OD
barbiturate tolerant individuals are cross-tolerant to other CNS depressants (alcohol, benzos,
general anesthetics) but not with ________ - ANS opioids
behavior pattern characterized by continued use of a psychoactive substance despite physical,
psychologic, or social harm - ANS addiction
benzodiazepine principal indications are - ANS anxiety, insomnia, seizure disorders
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,benzodiazepines adverse effects - ANS daytime sedation; anterograde amnesia
benzodiazepines are classified as Schedule - ANS IV
benzodiazepines are primarily for which two anxiety d/o's - ANS panic disorder, GAD
benzodiazepines produce their actions by enhancing the effects of _____, the principal
inhibitory neurotransmitter in the CNS - ANS GABA
benzodiazepines-like controlled substace approved for long-term use in insomnia -
ANS eszopiclone (Lunesta)
black box warnings - ANS a component of REMS
bridging agents commonly abused - ANS methadone, tramadol, buprenorphine (suboxone)
buprenorphine formulations used in management of opioid addiction - ANS subutex or
suboxone SL
butorphanol (stadol) and nalbuphne (nubain) are contraind. In MI as they - ANS increase
cardiac work
butrans transdermal sites must be rotated. No site may be reused within ___ days - ANS 21
cancer pain - ANS frequently undertreated, able to be mitigated in 90% of cases with proper
dosing/drug therapy (consider adjuvants)
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, chronic opioid therapy candidates can be identified with - ANS ORT (opioid risk tool); SOAPP
(screener and opioid assessment for patients with pain); DIRE (diagnois, intractability, risk, and
efficacy score)
chronic opioid therapy fails - ANS 50-70% of the time
code of fed regulations, title 21, section 1306 governs - ANS issuance & filling of prescriptions
codeine by itself is a schedule ___ CS. In cough meds, it's often schedule ___ - ANS II, V
complement effects of opioids (in combo with, not in substitution of) - ANS adjuvant
analgesics
Comprehensive Drug Abuse Prevention and Control Act (1970) - ANS establishes regulations
for controlled substances for manufacturers, prescribers, pharmacists, and distributors
Comprehensive Drug Abuse Prevention and Control Act (1970) aka - ANS Controlled
Substance Act
controlled substance definition - ANS any drug whose use is controlled by fed gov.
controlled substance prescriptions require - ANS actual number & numerical value
cross-tolerance does not exist between opioid agonists and - ANS general CNS depressants
cross-tolerance exists among - ANS various opioid agonists
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
