NRNP 6675 MIDTERM EXAM
Questions and Answers
1. Which of the following are risk factors for neuroleptic malignant syndrome?
(Select all that apply):
A. Age
B. Rapid Dose Escalation
C. Parental Route of Administration
D. Higher Potency Typical Antipsychotics
Answer: B, C, D, and A (Age) is often considered a risk factor, especially in older
individuals, though evidence is less definitive.
Explanation: Risk factors for neuroleptic malignant syndrome (NMS) include rapid
dose escalation, parenteral (injectable) administration, and use of high-potency
typical antipsychotics. Age can also increase vulnerability, particularly in elderly
patients (Medscape).
2. Antipsychotic medication provides D2 blockade in the meso-cortical
pathway causing which of the following effects?
A. Reduces negative symptoms
B. Increases EPS
C. Causes prolactinemia
D. Reduces positive symptoms
,Answer: B) Increases EPS
Explanation: D2 receptor blockade in the nigrostriatal pathway leads to
extrapyramidal symptoms (EPS), such as tremors and rigidity. While D2 blockade
can reduce positive symptoms, it is primarily associated with EPS.
3. Phencyclidine (PCP) and ketamine exert their unique behavioral effects by
blocking which of the following receptors?
A. GABA
B. Serotonin
C. Dopamine receptors
D. NMDA type receptors
Answer: D) NMDA type receptors
Explanation: PCP and ketamine are NMDA receptor antagonists, which produce
dissociative and hallucinogenic effects by blocking glutamate activity at NMDA
receptors (Psychiatry Online).
4. The diagnosis used to describe a syndrome characterized by specific
symptoms resulting from recent ingestion or exposure to a substance is known
as which of the following?
A. Substance intoxication
B. Substance withdrawal
C. Substance use disorder
D. All of the above
,Answer: A) Substance intoxication
Explanation: Substance intoxication involves physiological and behavioral changes
due to recent use of a substance. Substance use disorder is a broader diagnosis
involving problematic patterns of use (Sadock, p. 269).
5. Abnormal involuntary movements in a rhythmic pattern affecting the face,
mouth, tongue, and jaw is known as which of the following?
A. Akathisia
B. Dystonia
C. Tardive dyskinesia
D. EPS
Answer: C) Tardive dyskinesia
Explanation: Tardive dyskinesia is characterized by repetitive, involuntary
movements, especially of the face, mouth, and tongue, often caused by long-term
antipsychotic use.
6. A deeply held belief despite evidence to the contrary, lasting at least 1
month, without prominent hallucinations, with functional impairment that
relates to the delusional system is called:
A. Schizophrenia
B. Delusional disorder
C. Brief psychotic disorder
D. Schizophreniform disorder
, Answer: B) Delusional disorder
Explanation: Delusional disorder involves persistent delusions with little or no other
psychotic symptoms, and functioning may be relatively preserved outside the
delusional system.
7. Which of the following is true about preoccupation with castration?
A. This can be serious and life-threatening if castration is carried out without medical
supervision
B. Consistent with transvestic disorder
C. Other specified paraphilic disorder
D. Sexual masochism disorder
Answer: A) This can be serious and life-threatening if castration is carried out
without medical supervision
Explanation: Self-castration or preoccupation with castration can be dangerous and
requires medical intervention; it is not classified as a paraphilia.
8. Which of the following is a system that provides a uniform language for
describing medical and surgical procedures and diagnostic services rendered
by clinicians?
A. HIPAA
B. CPT
C. DSM-5
D. DRG
Questions and Answers
1. Which of the following are risk factors for neuroleptic malignant syndrome?
(Select all that apply):
A. Age
B. Rapid Dose Escalation
C. Parental Route of Administration
D. Higher Potency Typical Antipsychotics
Answer: B, C, D, and A (Age) is often considered a risk factor, especially in older
individuals, though evidence is less definitive.
Explanation: Risk factors for neuroleptic malignant syndrome (NMS) include rapid
dose escalation, parenteral (injectable) administration, and use of high-potency
typical antipsychotics. Age can also increase vulnerability, particularly in elderly
patients (Medscape).
2. Antipsychotic medication provides D2 blockade in the meso-cortical
pathway causing which of the following effects?
A. Reduces negative symptoms
B. Increases EPS
C. Causes prolactinemia
D. Reduces positive symptoms
,Answer: B) Increases EPS
Explanation: D2 receptor blockade in the nigrostriatal pathway leads to
extrapyramidal symptoms (EPS), such as tremors and rigidity. While D2 blockade
can reduce positive symptoms, it is primarily associated with EPS.
3. Phencyclidine (PCP) and ketamine exert their unique behavioral effects by
blocking which of the following receptors?
A. GABA
B. Serotonin
C. Dopamine receptors
D. NMDA type receptors
Answer: D) NMDA type receptors
Explanation: PCP and ketamine are NMDA receptor antagonists, which produce
dissociative and hallucinogenic effects by blocking glutamate activity at NMDA
receptors (Psychiatry Online).
4. The diagnosis used to describe a syndrome characterized by specific
symptoms resulting from recent ingestion or exposure to a substance is known
as which of the following?
A. Substance intoxication
B. Substance withdrawal
C. Substance use disorder
D. All of the above
,Answer: A) Substance intoxication
Explanation: Substance intoxication involves physiological and behavioral changes
due to recent use of a substance. Substance use disorder is a broader diagnosis
involving problematic patterns of use (Sadock, p. 269).
5. Abnormal involuntary movements in a rhythmic pattern affecting the face,
mouth, tongue, and jaw is known as which of the following?
A. Akathisia
B. Dystonia
C. Tardive dyskinesia
D. EPS
Answer: C) Tardive dyskinesia
Explanation: Tardive dyskinesia is characterized by repetitive, involuntary
movements, especially of the face, mouth, and tongue, often caused by long-term
antipsychotic use.
6. A deeply held belief despite evidence to the contrary, lasting at least 1
month, without prominent hallucinations, with functional impairment that
relates to the delusional system is called:
A. Schizophrenia
B. Delusional disorder
C. Brief psychotic disorder
D. Schizophreniform disorder
, Answer: B) Delusional disorder
Explanation: Delusional disorder involves persistent delusions with little or no other
psychotic symptoms, and functioning may be relatively preserved outside the
delusional system.
7. Which of the following is true about preoccupation with castration?
A. This can be serious and life-threatening if castration is carried out without medical
supervision
B. Consistent with transvestic disorder
C. Other specified paraphilic disorder
D. Sexual masochism disorder
Answer: A) This can be serious and life-threatening if castration is carried out
without medical supervision
Explanation: Self-castration or preoccupation with castration can be dangerous and
requires medical intervention; it is not classified as a paraphilia.
8. Which of the following is a system that provides a uniform language for
describing medical and surgical procedures and diagnostic services rendered
by clinicians?
A. HIPAA
B. CPT
C. DSM-5
D. DRG
