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NU578 - UNIT 1 EXAM STUDYGUIDE
QUESTIONS WITH ANSWERS.
Scopolamine (Transdermscop) - correct answer -ACh antagonist
(anticholinergic)
Used for motion sickness
Dicyclomine (Bentyl) - correct answer -ACh antagonist
Used fro irritable bowel
Trihexyphenidyl (Artane)
Benztropine (Cogentin) - correct answer -ACh antagonist
Used for parkinson's disease
Treatment of anticholinergic (antimuscarinic) poisoning - correct
answer -physostigmine
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*activated charcoal also used to decrease intestinal absorption
Darifenacin (Enablex)
Oxybutyinin (Ditropan)
Solifenacin (VESIcare)
Tolteridine (Detrol)
Trospium (Sanctura)
Fesoterodine (Toviaz) - correct answer -Anticholinergic
Block muscarinic receptors on the bladder detrusor muscle
Used for overactive bladder
Succinylcholine (Anectine) - correct answer -Depolarizing
neuromuscular blocker
Specific for ACh on skeletal muscle
Onset within 30 seconds
to 1 minute, duration of action about 5 minutes.
Used primarily to facilitate intubation or for endoscopy.
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Non-depolarizing (competitive) neuromuscular blockers - correct
answer -compete with acetylcholine for binding to Nicotinic-M
recepotors
Cause skeletal muscle paralysis
** Do not reduce consciousness of perception of pain
Curare Family:
(Atracurium
Cisatracurium
Pancuronium
Rocuronium
Vecuronium) - correct answer -Nondepolarizing neuromuscular
blocker
Specific for ACh on skeletal muscle
All work for about 20-40 min; recovery may take an
hour, given IV
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Used for longer surgical procedures, as adjuncts to
anesthesia.
***Watch for Malignant Hyperthermia as a side effect:
Malignant Hyperthermia - correct answer -presents as muscle
rigidity, tremors, and high fever soon
after exposure to these agents.
Treatment is to d/c the
causative drug, bring temperature down with cooling measures,
and treat muscle spasms with Dantrolene
Dantrolene
(Dantrium) - correct answer -Skeletal muscle relaxant
used to treat malignant hyperthermia
Other skeletal muscle relaxants - correct answer --
Benzodiazepines
- Baclofen (Lioresal)
NU578 - UNIT 1 EXAM STUDYGUIDE
QUESTIONS WITH ANSWERS.
Scopolamine (Transdermscop) - correct answer -ACh antagonist
(anticholinergic)
Used for motion sickness
Dicyclomine (Bentyl) - correct answer -ACh antagonist
Used fro irritable bowel
Trihexyphenidyl (Artane)
Benztropine (Cogentin) - correct answer -ACh antagonist
Used for parkinson's disease
Treatment of anticholinergic (antimuscarinic) poisoning - correct
answer -physostigmine
, Page | 2
*activated charcoal also used to decrease intestinal absorption
Darifenacin (Enablex)
Oxybutyinin (Ditropan)
Solifenacin (VESIcare)
Tolteridine (Detrol)
Trospium (Sanctura)
Fesoterodine (Toviaz) - correct answer -Anticholinergic
Block muscarinic receptors on the bladder detrusor muscle
Used for overactive bladder
Succinylcholine (Anectine) - correct answer -Depolarizing
neuromuscular blocker
Specific for ACh on skeletal muscle
Onset within 30 seconds
to 1 minute, duration of action about 5 minutes.
Used primarily to facilitate intubation or for endoscopy.
, Page | 3
Non-depolarizing (competitive) neuromuscular blockers - correct
answer -compete with acetylcholine for binding to Nicotinic-M
recepotors
Cause skeletal muscle paralysis
** Do not reduce consciousness of perception of pain
Curare Family:
(Atracurium
Cisatracurium
Pancuronium
Rocuronium
Vecuronium) - correct answer -Nondepolarizing neuromuscular
blocker
Specific for ACh on skeletal muscle
All work for about 20-40 min; recovery may take an
hour, given IV
, Page | 4
Used for longer surgical procedures, as adjuncts to
anesthesia.
***Watch for Malignant Hyperthermia as a side effect:
Malignant Hyperthermia - correct answer -presents as muscle
rigidity, tremors, and high fever soon
after exposure to these agents.
Treatment is to d/c the
causative drug, bring temperature down with cooling measures,
and treat muscle spasms with Dantrolene
Dantrolene
(Dantrium) - correct answer -Skeletal muscle relaxant
used to treat malignant hyperthermia
Other skeletal muscle relaxants - correct answer --
Benzodiazepines
- Baclofen (Lioresal)
