BMTCN CHAPTERS TEST BANK QUESTIONS AND ANSWERS
What is a patient who received a T-cell-depleted transplant at risk for developing within the first year
following transplant?
A. Acute myeloid leukemia
B. Breast cancer
C. Basal cell carcinoma
D. Post-transplant lymphoproliferative disorders - (ANSWER)D. Post-transplant lymphoproliferative
disorders
What is the most common secondary malignancy in pediatric patients who receive radiation as part of
the transplant conditioning regimen?
A. Esophageal cancer
B. Thyroid cancer
C. Nonsquamous cell carcinoma
D. Brain stem glioma - (ANSWER)C. Nonsquamous cell carcinoma
Which of the following is true of human papillomavirus (HPV) infections?
A. Exposure does not increase patients' risk of developing secondary cancers.
B. Because patients are not at a significant risk following transplant, vaccination is not necessary.
C. HPV can significantly increase patients' risk of developing post-transplant lymphoproliferative
disorder.
D. Patients between the ages of 9 and 26 should be revaccinated post-transplant with the HPV vaccine. -
(ANSWER)D. Patients between the ages of 9 and 26 should be revaccinated post-transplant with the HPV
vaccine.
With which of the following are post-transplant lymphoproliferative disorders strongly associated?
, BMTCN CHAPTERS TEST BANK QUESTIONS AND ANSWERS
A. Donor B cells infected with the Epstein-Barr virus (EBV)
B. Donor T cells infected with EBV
C. They are not associated with viral infections.
D. Sibling myeloablative transplants - (ANSWER)A. Donor B cells infected with the Epstein-Barr virus
(EBV)
Which of the following is NOT a risk for developing secondary solid tumors?
A. Genetic predisposition
B. Chronic graft-versus-host disease (GVHD)
C. An increased incidence within the first 12 months following transplant
D. Younger age at transplant - (ANSWER)C. An increased incidence within the first 12 months following
transplant
Acute myeloid leukemia without features of myelodysplastic syndrome is most often associated with
patients who received which of the following?
A. Fractionated total body irradiation
B. Antithymocyte globulin (ATG)
C. A topoisomerase II inhibitor
D. An alkylating agent - (ANSWER)C. A topoisomerase II inhibitor (doxorubicin, etoposide, and
mitoxantron)
The risk of ovarian failure, regardless of pubertal status, is associated with the use of which
chemotherapy?
A. Fludarabine and cyclophosphamide
B. Busulfan and cyclophosphamide
C. Etoposide and carmustine
What is a patient who received a T-cell-depleted transplant at risk for developing within the first year
following transplant?
A. Acute myeloid leukemia
B. Breast cancer
C. Basal cell carcinoma
D. Post-transplant lymphoproliferative disorders - (ANSWER)D. Post-transplant lymphoproliferative
disorders
What is the most common secondary malignancy in pediatric patients who receive radiation as part of
the transplant conditioning regimen?
A. Esophageal cancer
B. Thyroid cancer
C. Nonsquamous cell carcinoma
D. Brain stem glioma - (ANSWER)C. Nonsquamous cell carcinoma
Which of the following is true of human papillomavirus (HPV) infections?
A. Exposure does not increase patients' risk of developing secondary cancers.
B. Because patients are not at a significant risk following transplant, vaccination is not necessary.
C. HPV can significantly increase patients' risk of developing post-transplant lymphoproliferative
disorder.
D. Patients between the ages of 9 and 26 should be revaccinated post-transplant with the HPV vaccine. -
(ANSWER)D. Patients between the ages of 9 and 26 should be revaccinated post-transplant with the HPV
vaccine.
With which of the following are post-transplant lymphoproliferative disorders strongly associated?
, BMTCN CHAPTERS TEST BANK QUESTIONS AND ANSWERS
A. Donor B cells infected with the Epstein-Barr virus (EBV)
B. Donor T cells infected with EBV
C. They are not associated with viral infections.
D. Sibling myeloablative transplants - (ANSWER)A. Donor B cells infected with the Epstein-Barr virus
(EBV)
Which of the following is NOT a risk for developing secondary solid tumors?
A. Genetic predisposition
B. Chronic graft-versus-host disease (GVHD)
C. An increased incidence within the first 12 months following transplant
D. Younger age at transplant - (ANSWER)C. An increased incidence within the first 12 months following
transplant
Acute myeloid leukemia without features of myelodysplastic syndrome is most often associated with
patients who received which of the following?
A. Fractionated total body irradiation
B. Antithymocyte globulin (ATG)
C. A topoisomerase II inhibitor
D. An alkylating agent - (ANSWER)C. A topoisomerase II inhibitor (doxorubicin, etoposide, and
mitoxantron)
The risk of ovarian failure, regardless of pubertal status, is associated with the use of which
chemotherapy?
A. Fludarabine and cyclophosphamide
B. Busulfan and cyclophosphamide
C. Etoposide and carmustine
