PHA 317 Final Cumulative UPDATED
ACTUAL Questions and CORRECT
Answers
Which of the following factors can affect diffusion of drug? i.Concentration gradient
ii.Particle size
iii.Thickness of the diffusion barrier
a.Only i is correct
b.Only ii is correct
c.Only iii is correct
d.All I, ii and iii are correct
e.None of the options is correct - CORRECT ANSWER - d.All I, ii and iii are correct
Which of the following statements about zero order reaction is/are correct?
i.The rate of reaction is dependent on the concentration of reactant(s).
ii.The half-life = 0.693/k where k is zero order reaction rate constant. a. Only i is correct
b. Only ii is correct
c. Both are correct
d.Neither i nor ii is correct. - CORRECT ANSWER - d.Neither i nor ii is correct.
The degradation of local anesthetic procaine can be prevented by making its complex with
a.caffeine
b.calcium
c.sodium
d.potassium - CORRECT ANSWER - a.caffeine
A drug may be degraded chemically by
i.either hydrolysis or oxidation but not by both
,ii.either hydrolysis or oxidation and even by both
a.only (i) is correct
b.neither (i) nor (ii) is correct
c.only (ii) is correct
d.both (i) and (ii) are correct - CORRECT ANSWER - c.only (ii) is correct
The empty spaces in parenteral vials or ampoules are filled with nitrogen to prevent the
degradation of drugs by:
a.oxidation
b.photolysis
c.isomerization
d.hydrolysis - CORRECT ANSWER - a.oxidation
Which is not effective against photolysis?
a.using an amber colored container
b.coating a tablet with cellulose acetate phthalate
c.coating a tablet with UV absorbing material such as vinyl acetate containing oxybenzone.
d.storing in the dark - CORRECT ANSWER - b.coating a tablet with cellulose acetate
phthalate
The overall degradation in case of a suspension is usually:
a. zero order
b.second order
c.third order
d.None of the above - CORRECT ANSWER - a. zero order
In a zero order reaction, the rate of decomposition is dependent on the concentration of one of
the reactants.
a.True
, b.False - CORRECT ANSWER - b.False
In a zero order reaction:
i.the rate of decomposition is dependent on the concentration of one of the reactants
ii.the rate of decomposition is independent of the concentration of reactants
iii.A plot of the amount remaining (as ordinate) against time (abscissa) is linear with a slope of
1/k
a.only ii is correct
b.none is correct
c.only iii is correct
d.only i is correct - CORRECT ANSWER - a.only ii is correct
In a zero order reaction:
i.the half-life is equal to 0.693/k
ii.the unit of k is concentration / time
iii.a plot of the amount remaining (as ordinate) against time (abscissa) is linear with a slope of
1/k
a.none is correct
b.only ii is correct
c.only i is correct
d.only iii is correct - CORRECT ANSWER - b.only ii is correct
In a second order reaction:
i.The rate of reaction depends on the concentration of two reacting species.
ii.A plot of time (as abscissa) against ቂబି ௫ బቃ (as ordinate) is linear with a slope equal to
1/k2
iii.The half-life is independent of concentration
a.none is correct
b.only i is correct
ACTUAL Questions and CORRECT
Answers
Which of the following factors can affect diffusion of drug? i.Concentration gradient
ii.Particle size
iii.Thickness of the diffusion barrier
a.Only i is correct
b.Only ii is correct
c.Only iii is correct
d.All I, ii and iii are correct
e.None of the options is correct - CORRECT ANSWER - d.All I, ii and iii are correct
Which of the following statements about zero order reaction is/are correct?
i.The rate of reaction is dependent on the concentration of reactant(s).
ii.The half-life = 0.693/k where k is zero order reaction rate constant. a. Only i is correct
b. Only ii is correct
c. Both are correct
d.Neither i nor ii is correct. - CORRECT ANSWER - d.Neither i nor ii is correct.
The degradation of local anesthetic procaine can be prevented by making its complex with
a.caffeine
b.calcium
c.sodium
d.potassium - CORRECT ANSWER - a.caffeine
A drug may be degraded chemically by
i.either hydrolysis or oxidation but not by both
,ii.either hydrolysis or oxidation and even by both
a.only (i) is correct
b.neither (i) nor (ii) is correct
c.only (ii) is correct
d.both (i) and (ii) are correct - CORRECT ANSWER - c.only (ii) is correct
The empty spaces in parenteral vials or ampoules are filled with nitrogen to prevent the
degradation of drugs by:
a.oxidation
b.photolysis
c.isomerization
d.hydrolysis - CORRECT ANSWER - a.oxidation
Which is not effective against photolysis?
a.using an amber colored container
b.coating a tablet with cellulose acetate phthalate
c.coating a tablet with UV absorbing material such as vinyl acetate containing oxybenzone.
d.storing in the dark - CORRECT ANSWER - b.coating a tablet with cellulose acetate
phthalate
The overall degradation in case of a suspension is usually:
a. zero order
b.second order
c.third order
d.None of the above - CORRECT ANSWER - a. zero order
In a zero order reaction, the rate of decomposition is dependent on the concentration of one of
the reactants.
a.True
, b.False - CORRECT ANSWER - b.False
In a zero order reaction:
i.the rate of decomposition is dependent on the concentration of one of the reactants
ii.the rate of decomposition is independent of the concentration of reactants
iii.A plot of the amount remaining (as ordinate) against time (abscissa) is linear with a slope of
1/k
a.only ii is correct
b.none is correct
c.only iii is correct
d.only i is correct - CORRECT ANSWER - a.only ii is correct
In a zero order reaction:
i.the half-life is equal to 0.693/k
ii.the unit of k is concentration / time
iii.a plot of the amount remaining (as ordinate) against time (abscissa) is linear with a slope of
1/k
a.none is correct
b.only ii is correct
c.only i is correct
d.only iii is correct - CORRECT ANSWER - b.only ii is correct
In a second order reaction:
i.The rate of reaction depends on the concentration of two reacting species.
ii.A plot of time (as abscissa) against ቂబି ௫ బቃ (as ordinate) is linear with a slope equal to
1/k2
iii.The half-life is independent of concentration
a.none is correct
b.only i is correct
