CORRECT Answers
How are lipids carried - CORRECT ANSWER -on lipoproteins in the blood because they
are insoluble in water
Proteins found on lipoproteins - CORRECT ANSWER -apolipoproteins
Density of lipoprotein with less lipid and greater protein - CORRECT ANSWER -more
dense
Density of lipoprotein with more lipids and less protein - CORRECT ANSWER -less
dense
Major bloodstream lipoproteins - CORRECT ANSWER -chylomicrons, vLDL, LDL,
HDL
Chylomicrons - CORRECT ANSWER -least dense of the lipoproteins and are triglyceride-
rich particles that are formed in the intestine
Function of Chylomicrons and where they can be found - CORRECT ANSWER -
Transport dietary fat and can be found in the bloodstream at highest concentration soon after a
meal
Least to most dense lipoprotein particles - CORRECT ANSWER -Chlyomicron, vLDL,
LDL, HDL
lipoprotein that is the most atherogenic of all lipoproteins - CORRECT ANSWER -LDL
LDL carries - CORRECT ANSWER -60-70% of the cholesterol in the blood
,HDL carries - CORRECT ANSWER -20-30% of the cholesterol in the blood
Equation for total LDL-C in bloodstream - CORRECT ANSWER -LDL= TC-(HDL-C-
(TG/5))
When does calculating LDL-C become inaccurate - CORRECT ANSWER -when TG
exceeds 400mg/dL
Desirable total cholesterol level - CORRECT ANSWER -<200
Borderline high total cholesterol level - CORRECT ANSWER -200-240
High total cholesterol level - CORRECT ANSWER ->240
Optimal TG level - CORRECT ANSWER -<150
Borderline high TG level - CORRECT ANSWER -150-199
High TG level - CORRECT ANSWER -200-499
Very high TG levels - CORRECT ANSWER ->500
Optimal in men HDL levels - CORRECT ANSWER ->40
Optimal in women HDL levels - CORRECT ANSWER ->50
Optimal LDL-C levels - CORRECT ANSWER -<100
,Near optimal LDL-C levels - CORRECT ANSWER -100-129
Borderline high LDL-C levels - CORRECT ANSWER -130-159
High LDL-C levels - CORRECT ANSWER -160-189
Very high LDL-C levels - CORRECT ANSWER ->190
Hypertriglycerdemia is associated with high levels of - CORRECT ANSWER -VLDL-C
Non-HDL-Cholesterol calculation - CORRECT ANSWER -HDL-C - Total cholesterol
Atherogenic dyslipidemia - CORRECT ANSWER -Elevated levels of TG, low HDL-C
and only modest elevations of LDL-C
Metabolic syndrome - CORRECT ANSWER -requires the presence of any 3 of the
following conditions: abdominal obesity, elevated TG, low HDL, elevated BP and
hyperglycemia
Criteria for metabolic syndrome: Abdominal obesity - CORRECT ANSWER -WC >102
cm (40 in) for men
WC >88cm (35 in) for women
Criteria for metabolic syndrome: Hypertriglyceremia - CORRECT ANSWER -≥150 or
drug treatment
Criteria for metabolic syndrome: Low HDL - CORRECT ANSWER -<40 for men
<50 for women
, Criteria for metabolic syndrome: Elevated BP - CORRECT ANSWER -SBP ≥130
DBP ≥85
or drug treatment
Criteria for metabolic syndrome: Hyperglycemia - CORRECT ANSWER -Fasting glucose
≥100
or drug treatment
AACVPR understanding of atherosclerosis - CORRECT ANSWER -Traditional risk
factors are a source of inflammatory changes in the blood vessel wall --> which attract lipid
laden macrophages and other inflammatory cells to enter the blood vessel wall --> where they
proliferate and develop atherosclerotic plaques --> which are the source of the clinical
manifestations of CHD
Fatty streaks - CORRECT ANSWER -lipid deposition (daily lipid laden macrophages) in
the arterial wall
Lumen - CORRECT ANSWER -opening inside of the blood vessel
fibrous plaque - CORRECT ANSWER -Larger and more obstructive lesoions consisting
of an outer fibrous
Why do plaque ruptures occurs prior to the development of cardiovascular symptoms in many
cases - CORRECT ANSWER -Atherosclerotic plaques that are prone to rupture tend to be
younger, more immature plaques that usually do not produce the degree of luminal narrowing
required to develop exertion symptoms
What occurs after a plaque rupture - CORRECT ANSWER -Clot formation within the
lumen of the coronary artery, potential resulting in an acute coronary syndrome from the sudden
development of severe obstruction to coronary blood flow