Questions & Answers 2025 _2026
Advanced Pharmacology – Endocrine, GI, GU, Pain, Psych, & Special
Topics
Batch 1: Questions 1–200
1. A patient taking metformin develops acute renal failure.
What is the priority action?
Answer: Discontinue metformin immediately to prevent lactic acidosis.
2. Which insulin has the fastest onset of action?
Answer: Insulin lispro.
3. A patient on levothyroxine reports palpitations and
insomnia. What is the likely cause?
Answer: Overreplacement leading to iatrogenic hyperthyroidism.
4. Which drug is preferred for diabetic neuropathic pain?
Answer: Duloxetine.
,5. A woman taking spironolactone should be monitored
for which key electrolyte abnormality?
Answer: Hyperkalemia.
6. Which medication is first-line for Helicobacter pylori
infection?
Answer: Clarithromycin-based triple therapy.
7. Long-term use of PPIs increases the risk of which
condition?
Answer: Bone fractures due to decreased calcium absorption.
8. A patient using sildenafil must avoid which
medication?
Answer: Nitrates.
9. Which drug is the preferred initial therapy for
osteoporosis in postmenopausal women?
Answer: Alendronate.
10. Which adverse effect is most associated with statins?
Answer: Rhabdomyolysis (muscle toxicity).
, 11. Which medication is indicated for acute adrenal
crisis?
Answer: IV hydrocortisone.
12. What is the black box warning for metoclopramide?
Answer: Tardive dyskinesia with long-term use.
13. Which drug is safest for treating hypertension in
pregnancy?
Answer: Labetalol.
14. A patient taking warfarin has an INR of 8 but no
bleeding. What is the recommended treatment?
Answer: Oral vitamin K.
15. Which oral antidiabetic class causes the highest risk
of hypoglycemia?
Answer: Sulfonylureas.
16. Which pain medication is contraindicated after
bariatric surgery?