AAB MT HEMATOLOGY ACTUAL EXAM
PAPER 2026 TESTED QUESTIONS AND
COMPLETE SOLVED SOLUTION
⩥ What disorder does a defect in heme synthesis lead to? Answer:
porphyria
⩥ What is the function of the enzyme methemoglobin-cytochrome C
reductase in a red blood cell? Answer: to keep iron in the ferrous state
⩥ Which hemoglobin has a 200 times greater binding capacity for the
hemoglobin molecule than oxygen? Answer: carboxyhemoglobin
⩥ What product is formed when ferrous iron of hemoglobin is oxidized
to the ferric state? Answer: methemoglobin
⩥ Which hemoglobin derivative causes irreversible changes in teh red
blood cells? Answer: sulfhemoglobin
⩥ Which of the following hemoglobins is NOT normally present in a
normal adult Answer: Hb-S
,⩥ Which embryonic hemoglobin is normally found in newborns
Answer: Hb-F
⩥ What is the most abundant hemoglobin in a newborn? Answer: Hb-F
⩥ What is the molecular structure of hemoglobin S? Answer: Valine
replaces glutamic acid in the 6th position of the beta chain
⩥ Which of the following hemoglobins is insoluble under lowered
oxygen tensions? Answer: Hb-S
⩥ What laboratory test is used to confirm the specific diagnosis of sickle
cell anemia Answer: hemoglobin electrophoresis
⩥ In the solubility test for hemoglobin S, what is the reagent responsible
for the reduction of the hemoglobin molecule? Answer: sodium
dithionite
⩥ In hemoglobin C, what replaces glutamic acid? Answer: lysine
⩥ Which RBC inclusion is characteristic of hemoglobin C disease?
Answer: rod-shaped crystals
, ⩥ What is hemoglobin F composed o? Answer: 2 alpha + 2 gamma
chains
⩥ Which hemoglobin is resistant to alkali denaturation Answer: Hb-F
⩥ What hemoglobin's are differentiated by the Kleihauer-Betke
technique Answer: Hd-A1 from Hb-F
⩥ What is the order of migration of hemoglobins, from fastest to
slowest, on cellulose acetate at pH 8.4 Answer: A1, F, S,C
⩥ Why is citrate agar used when abnormal hemoglobins are identified
on cellulose acetate at pH 8.6? Answer: It seperates hemoglobin S from
hemoglobin D
⩥ The cyanmethemoglobin method measures all hemoglobin pigments
EXCEPT which one? Answer: sulfhemoglobin
⩥ What is the diluent in the cyanmethhemoglobin method for the
determination of hemoglobin? Answer: Drabkin's solution
⩥ What is the normal plasma hemoglobin concentration? Answer: 2-3
mg/dL
PAPER 2026 TESTED QUESTIONS AND
COMPLETE SOLVED SOLUTION
⩥ What disorder does a defect in heme synthesis lead to? Answer:
porphyria
⩥ What is the function of the enzyme methemoglobin-cytochrome C
reductase in a red blood cell? Answer: to keep iron in the ferrous state
⩥ Which hemoglobin has a 200 times greater binding capacity for the
hemoglobin molecule than oxygen? Answer: carboxyhemoglobin
⩥ What product is formed when ferrous iron of hemoglobin is oxidized
to the ferric state? Answer: methemoglobin
⩥ Which hemoglobin derivative causes irreversible changes in teh red
blood cells? Answer: sulfhemoglobin
⩥ Which of the following hemoglobins is NOT normally present in a
normal adult Answer: Hb-S
,⩥ Which embryonic hemoglobin is normally found in newborns
Answer: Hb-F
⩥ What is the most abundant hemoglobin in a newborn? Answer: Hb-F
⩥ What is the molecular structure of hemoglobin S? Answer: Valine
replaces glutamic acid in the 6th position of the beta chain
⩥ Which of the following hemoglobins is insoluble under lowered
oxygen tensions? Answer: Hb-S
⩥ What laboratory test is used to confirm the specific diagnosis of sickle
cell anemia Answer: hemoglobin electrophoresis
⩥ In the solubility test for hemoglobin S, what is the reagent responsible
for the reduction of the hemoglobin molecule? Answer: sodium
dithionite
⩥ In hemoglobin C, what replaces glutamic acid? Answer: lysine
⩥ Which RBC inclusion is characteristic of hemoglobin C disease?
Answer: rod-shaped crystals
, ⩥ What is hemoglobin F composed o? Answer: 2 alpha + 2 gamma
chains
⩥ Which hemoglobin is resistant to alkali denaturation Answer: Hb-F
⩥ What hemoglobin's are differentiated by the Kleihauer-Betke
technique Answer: Hd-A1 from Hb-F
⩥ What is the order of migration of hemoglobins, from fastest to
slowest, on cellulose acetate at pH 8.4 Answer: A1, F, S,C
⩥ Why is citrate agar used when abnormal hemoglobins are identified
on cellulose acetate at pH 8.6? Answer: It seperates hemoglobin S from
hemoglobin D
⩥ The cyanmethemoglobin method measures all hemoglobin pigments
EXCEPT which one? Answer: sulfhemoglobin
⩥ What is the diluent in the cyanmethhemoglobin method for the
determination of hemoglobin? Answer: Drabkin's solution
⩥ What is the normal plasma hemoglobin concentration? Answer: 2-3
mg/dL
