Answers 2025|2026 verified graded A+
already passed!
Because of tautomeric shift-induced mismatches, DNA replication can
be no more accurate than ______ mutations/base pair - correct answer-
10^-4 mutation/base pairs
Each base can appear in one of several forms called______ which are
tisomers that differ in the position of their atoms and bonds - correct
answer-tautomers
4 bases can exist in 2 tautomeric forms: A/C which can be in amino or
imino forms. Or G/T(U) which can be in keto or enol forms.
Describe the difference - correct answer-Amino and keto are the more
common and most stable.
Imino and enol may form a pair with the wrong base forming a mispair.
A change that has no effect on the protein's sequence: __1__
,A __2__ is when a different amino acid is put into the resulting
polypeptide. The effects of this mutation depend on how chemically
different the new amino acid is from the wild-type amino acid, and
location is important.
A __3__ converts a codon encoding an amino acid into a stop codon,
resulting in a shorter protein than the wild-type. - correct answer-1-
silent
2- missense
3- nonsense
Mutations can also be the result of an addition of a base: __1__
or the removal of a base: __2__
__3__ caused by the above mutations are problematic because they
shift the reading frame results.
-> can change every amino acid after the point mutation - correct
answer-1-insertion
2-deletion
3-frameshift mutation
Altering the amount of protein product produced by a gene: __1__
, and affect regions such as promotors, introns, regions coding for 5'-UTR
and 3'-UTR.
__2__ alter the concensus sequence of nucleotides and interference
with efficient transcription initiation.
__3__ reduce or eliminate normal pre-mRNA splicing. *cryptic splice
sites are produced by certain base-pair substitution mutations that
replace or compete with the original splice sites during pre-mRNA
processing.
__4__ caused by base-pair substitution of the 5' AAUAAA 3' signal
sequence can clock proper 3' processing of mRNA - correct answer-1-
regulatory mutation
2-promotor mutations
3- splicing mutations
4- poladenylation mutations
What in the enzyme involved in proofreading and how does work? -
correct answer-DNA pol- reads the newly added base, ensuring that it is
complementary to the corresponding base in the template strand
before adding the next one.
in proofreading, what happens if an incorrect base has been added? -
correct answer-If an incorrect base has been added the enzyme moves