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Exam (elaborations)

12 – Myocardial Infarction (MI): Pathophysiology, Treatment, and Essential Nursing Tips

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This comprehensive guide explains the pathophysiology, clinical presentation, diagnostic findings, treatment options, and nursing responsibilities related to Myocardial Infarction (MI). Designed for Med Surg students, this resource covers cardiac ischemia, STEMI vs NSTEMI, priority interventions, medications, ECG changes, and evidence-based nursing care tips. Ideal for nursing exam preparation, NCLEX review, and clinical practice support.

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MI - Myocardial Infarction
Pathophysiology Course


Pathophysiology Diagnostics
Myocardial Infarction (MI) the heart muscles DIE “necrosis” 1st–EKG
from lack of oxygen. This occurs when there is a (Any chest pain or MI symptoms)
blockage of the coronary arteries, the “O2 tubes”
feeding the heart oxygen.

Signs & Symptoms
O2

PAIN–Jaw, back, mid back/shoulder pain, heartburn (epigastric),
Substernal Normal ST elevation ST Depression
Key words = priority: “Sudden” “Crushing” “radiating” NCLEX TIP
SOB “dyspnea” “labored breathing”
NAUSEA Vomiting “Abdominal pain”
SWEATING “Diaphoresis”
PALE COOL SKIN “dusky”
ANXIETY

Causes
SODDA 2nd–LABS
T–Troponin (Over 0.5 ng/mL) T–
S–Stress, Smoking, Stimulants (caffeine, amphetamines) Trauma (ONLY indicator of MI)
O–Obesity–(BMI over 25) D– Other labs: Crp, Ckmb,
Diabetes & HTN (over 140/90) D– Myoglobin, CRP (inflammation)
Diet (high cholesterol) animal fats
A–African American males & Age (over 50) Treatment: Pharmacology
*Men more than women

Progression O–Oxygen A–
Asa
CAM N–Nitro–under tongue x 3 Max
M–Morphine - Any pain after = MI (injury)
C–CAD “coronary artery disease”
A–ACS “acute coronary syndrome” AFTER–MI
Angina - Stable “Safer”- relieved w/rest
Stabilization:
Angina - Unstable “Unsafe” - Unrelieved Heparin: prevents CLOT growth (NOT dissolve only t-PA)
M–MI (heart die) PTT: 46 - 70 “3 x MAX” Antidote: Protamine Sulfate
Memory Trick: “HaPTT” frog
Rest:
B–Beta Blockers (-lol) Atenolol
Blocks both BP & HR (Lol = Low BP & HR)
CAUTION:
B–Bad for Heart Failure patients (CHF)
B–Bradycardia (60 or Less) & BP low (HR LESS than 60)
Nursing Interventions B–Breathing Problems “wheezing” (Asthma, COPD) B–
Blood sugar masking “hides s/s” (Diabetics)
DRESS C–Calcium Channel Blockers
D–Diet low (sodium & fluids (2g/2L per day) Calms BP & HR-(AVOID Low Hr & BP)
Prevent HF Heart Failure=Heavy Fluid (Nifedipine, Diltiazem, Verapamil)
-dipine “declined BP & HR”
Report "New, Rapid" Weight Gain-Water Gain! -zem “zen yoga for heart”
R–Reduce Stress, Alcohol, Caffeine, Cholesterol (animal fats) -amil “chill heart”
E–Exercise (30 min x 5 days/wk)
S–Smoking Cessation
S–Sex (2 flights of stairs with NO SOB) NO viagra “-afil” Sildenafil = DEATH!
*AVOID NSAIDS (naproxen, ibuprofens) = increases CLOT risk!

Treatment: Pharmacology DISCHARGE–GOING HOME
AC–Anti Clogging of Arteries Heart Rest:
1st choice A–Ace (-pril) Lisonopril “chill pril”
A–Antiplatelet HOLD if: Platelets 50K or LESS CHOLESTEROL
2nd choice A–ARBs (-sartan) Losartan “relax man”
“below 50 gets risky” (not INR, not aPTT) PANEL
Antihypertensive (BP ONLY) *HOLD: Low BP (not HR)
A–ASA C-CLOGGED ARTERIES (risk) Precautions:
A–Avoid Pregnancy
C–Clopidogrel 200 or Less-Total Cholesterol A–Angioedema “thick tongue”
C–Cholesterol Lowering “-Statin” 150 or Less-Triglycerides
(Airway Risk) *only Ace NCLEX TIP
100 or Less-LDL
Lovastatin “stay clean” C–Cough *only Ace
Creatinine (Kidney) (normal: 0.9 -1.2) *only Ace
CAUTION: 40 or More = HDL
E–Elevated K+ (normal 3.5-5.0) NCLEX TIP
NO grapefruit AVOID Salt Substitues + Green Leafy veggies
Liver Toxic–report “clay colored stools” • 1st–Cardiac Monitor
• High Potassium = High Pump
Muscle pain (Rhabdomyolysis risk)
• Monitor: muscle cramps, spasms,
Late night–take at dinner peaked T waves, ST changes

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