Match the antiemetic with its drug class
Drug Classes
Substance P/Neurokinin 1 Antagonists
Serotonin antagonists
Cannabinoids
Antihistamine
Antiemetics
Ondansetron
Dronabinol
Dexamethasone
,Aprepitant
Meclizine
Give this one a try later!
Substance P/Neurokinin 1 Antagonists --> Aprepitant
Serotonin antagonists --> Ondansetron
Cannabinoids --> Dronabinol
Antihistamine --> Meclizine
Which teaching points would be shared by a nurse with a patient who is receiving
metoclopramide as orally disintegrating tablets?
Select all that apply.
Expect that metoclopramide may cause diarrhea.
Continue taking metoclopramide, even upon feeling better.
Avoid driving or other hazardous activities until stabilized on the medication.
Place the medication on the tongue, allowing it to dissolve before swallowing.
Avoid alcohol when receiving metoclopramide because this can increase sedation.
Give this one a try later!
Continue taking metoclopramide, even upon feeling better.
Metoclopramide should be continued, even if the patient is feeling better.
Avoid driving or other hazardous activities until stabilized on the
medication.
Because of sedation, the patient should be advised to avoid driving or
other hazardous activities until the patient has stabilized on the medication.
Place the medication on the tongue, allowing it to dissolve before
swallowing.
For orally disintegrating tablets, the tablet should be placed on the tongue,
allowed to dissolve, and then swallowed.
Avoid alcohol when receiving metoclopramide because this can increase
sedation.
, Patients receiving metoclopramide should be advised to avoid alcohol due
to a risk for sedation.
Rationale for Incorrect:
Constipation, not diarrhea, is an anticipated side effect of metoclopramide.
Which statement is accurate regarding the pharmacokinetics of sucralfate?
Sucralfate is rapidly absorbed from the gastrointestinal (GI) tract.
The drug is widely distributed and highly protein bound.
Sucralfate undergoes extensive hepatic metabolism.
The drug is excreted in the feces.
Give this one a try later!
The drug is excreted in the feces.
Sucralfate is excreted in the feces.
Rationale for Incorrect:
Sucralfate has an absorption of less than 5% by the GI tract. It is not rapidly
absorbed.
The drug acts locally at the site of the ulcer. It is not widely distributed or
highly protein bound.
Sucralfate does not undergo metabolism because it acts directly on the
ulcer.
A nurse is caring for a 78-year-old patient with Parkinson disease who is receiving
metoclopramide. The patient is noted to make repetitive mouth and tongue
movements as well as facial grimacing. Which adverse effect would a nurse suspect
this patient is experiencing from metoclopramide therapy?
Epilepsy
Agranulocytosis
Tardive dyskinesia
Neuroleptic malignant syndrome
Give this one a try later!
, Tardive dyskinesia
Tardive dyskinesia is most likely what this patient is experiencing. It is an
adverse effect that may occur with chronic treatment of metoclopramide
and in older adults. This is characterized by facial grimacing, sticking the
tongue out, and mouth movements, which are occurring in this patient.
Which patient has an indication to safely receive misoprostol?
A patient with severe diarrhea
A patient with diabetic gastroparesis
A patient with peptic ulcers who is pregnant
A patient with rheumatoid arthritis who is taking NSAIDs
Give this one a try later!
A patient with rheumatoid arthritis who is taking NSAIDs
A patient with rheumatoid arthritis who is receiving NSAIDs may receive
misoprostol to prevent the risk for NSAID-induced gastric ulcers.
Rationale for Incorrect:
A patient with diarrhea is not a candidate for treatment with misoprostol.
Misoprostol is not indicated to treat diarrhea and may cause diarrhea as a
side effect of therapy.
Metoclopramide, not misoprostol, is a treatment option for diabetic
gastroparesis.
Misoprostol is used to reduce the risk for nonsteroidal antiinflammatory
drug (NSAID)–induced gastric ulcers. It should never be used in a patient
who is pregnant because it can terminate the pregnancy.
A nurse is caring for a patient who takes calcium carbonate and was recently
prescribed ciprofloxacin, a quinolone, for a urinary tract infection. Which teaching
point would the nurse share with this patient about administration of these drugs?
These two drugs may be safely taken together on an empty stomach.
Take calcium carbonate 1 to 2 hours after ciprofloxacin.
Take ciprofloxacin 1 to 2 hours after calcium carbonate.
Drug Classes
Substance P/Neurokinin 1 Antagonists
Serotonin antagonists
Cannabinoids
Antihistamine
Antiemetics
Ondansetron
Dronabinol
Dexamethasone
,Aprepitant
Meclizine
Give this one a try later!
Substance P/Neurokinin 1 Antagonists --> Aprepitant
Serotonin antagonists --> Ondansetron
Cannabinoids --> Dronabinol
Antihistamine --> Meclizine
Which teaching points would be shared by a nurse with a patient who is receiving
metoclopramide as orally disintegrating tablets?
Select all that apply.
Expect that metoclopramide may cause diarrhea.
Continue taking metoclopramide, even upon feeling better.
Avoid driving or other hazardous activities until stabilized on the medication.
Place the medication on the tongue, allowing it to dissolve before swallowing.
Avoid alcohol when receiving metoclopramide because this can increase sedation.
Give this one a try later!
Continue taking metoclopramide, even upon feeling better.
Metoclopramide should be continued, even if the patient is feeling better.
Avoid driving or other hazardous activities until stabilized on the
medication.
Because of sedation, the patient should be advised to avoid driving or
other hazardous activities until the patient has stabilized on the medication.
Place the medication on the tongue, allowing it to dissolve before
swallowing.
For orally disintegrating tablets, the tablet should be placed on the tongue,
allowed to dissolve, and then swallowed.
Avoid alcohol when receiving metoclopramide because this can increase
sedation.
, Patients receiving metoclopramide should be advised to avoid alcohol due
to a risk for sedation.
Rationale for Incorrect:
Constipation, not diarrhea, is an anticipated side effect of metoclopramide.
Which statement is accurate regarding the pharmacokinetics of sucralfate?
Sucralfate is rapidly absorbed from the gastrointestinal (GI) tract.
The drug is widely distributed and highly protein bound.
Sucralfate undergoes extensive hepatic metabolism.
The drug is excreted in the feces.
Give this one a try later!
The drug is excreted in the feces.
Sucralfate is excreted in the feces.
Rationale for Incorrect:
Sucralfate has an absorption of less than 5% by the GI tract. It is not rapidly
absorbed.
The drug acts locally at the site of the ulcer. It is not widely distributed or
highly protein bound.
Sucralfate does not undergo metabolism because it acts directly on the
ulcer.
A nurse is caring for a 78-year-old patient with Parkinson disease who is receiving
metoclopramide. The patient is noted to make repetitive mouth and tongue
movements as well as facial grimacing. Which adverse effect would a nurse suspect
this patient is experiencing from metoclopramide therapy?
Epilepsy
Agranulocytosis
Tardive dyskinesia
Neuroleptic malignant syndrome
Give this one a try later!
, Tardive dyskinesia
Tardive dyskinesia is most likely what this patient is experiencing. It is an
adverse effect that may occur with chronic treatment of metoclopramide
and in older adults. This is characterized by facial grimacing, sticking the
tongue out, and mouth movements, which are occurring in this patient.
Which patient has an indication to safely receive misoprostol?
A patient with severe diarrhea
A patient with diabetic gastroparesis
A patient with peptic ulcers who is pregnant
A patient with rheumatoid arthritis who is taking NSAIDs
Give this one a try later!
A patient with rheumatoid arthritis who is taking NSAIDs
A patient with rheumatoid arthritis who is receiving NSAIDs may receive
misoprostol to prevent the risk for NSAID-induced gastric ulcers.
Rationale for Incorrect:
A patient with diarrhea is not a candidate for treatment with misoprostol.
Misoprostol is not indicated to treat diarrhea and may cause diarrhea as a
side effect of therapy.
Metoclopramide, not misoprostol, is a treatment option for diabetic
gastroparesis.
Misoprostol is used to reduce the risk for nonsteroidal antiinflammatory
drug (NSAID)–induced gastric ulcers. It should never be used in a patient
who is pregnant because it can terminate the pregnancy.
A nurse is caring for a patient who takes calcium carbonate and was recently
prescribed ciprofloxacin, a quinolone, for a urinary tract infection. Which teaching
point would the nurse share with this patient about administration of these drugs?
These two drugs may be safely taken together on an empty stomach.
Take calcium carbonate 1 to 2 hours after ciprofloxacin.
Take ciprofloxacin 1 to 2 hours after calcium carbonate.
