TEST BANK
p3
Introduction to Genetic Analysis
p3 p3 p3
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
12th Edition
p3
,Table of Contents
p3 p3
Chapter 01 The Genetics Revolution
p3 p3 p3 p3 1
Chapter 02 Single Gene Inheritance
p3 p3 p3 p3 6
Chapter 03 Independent Assortment of Genes
p3 p3 p3 p3 p3 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
p3 p3 p3 p3 p3 p3 43
Chapter 05 Gene Interaction
p3 p3 p3 63
Chapter 06 The Genetics of Bacteria and Their Viruses
p3 p3 p3 p3 p3 p3 p3 p3 84
Chapter 07 DNA Structure and Replication
p3 p3 p3 p3 p3 104
Chapter 08 RNA Transcription Processing and Decay
p3 p3 p3 p3 p3 p3 117
Chapter 09 Proteins and Their Synthesis
p3 p3 p3 p3 p3 130
Chapter 10 Gene Isolation and Manipulation
p3 p3 p3 p3 p3 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
p3 p3 p3 p3 p3 p3 p3 175
Chapter 13 The Genetic Control of Development
p3 p3 p3 p3 p3 p3 184
Chapter 14 Genomes and Genomics
p3 p3 p3 p3 192
Chapter 15 DNA Damage Repair and Recombination
p3 p3 p3 p3 p3 p3 197
Chapter 16 The Dynamic Genome Transposable Elements
p3 p3 p3 p3 p3 p3 216
Chapter 17 Large Scale Chromosomal Changes
p3 p3 p3 p3 p3 225
Chapter 18 Population Genetics
p3 p3 p3 243
Chapter 19 The Inheritance of Complex Traits
p3 p3 p3 p3 p3 p3 258
Chapter 20 Evolution of Genes and Traits
p3 p3 p3 p3 p3 p3 270
, Test Bank - Introduction to Genetic Analysis, 12th Edition (Griffiths, 2021)
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
Chapter 01: The Genetics Revolution
p3 p3 p3 p3
1. The early 1900s was an important period for genetics due to which of the following major events?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. the rediscovery of Gregor Mendel's scientific findings
p3 p3 p3 p3 p3 p3
b. Watson and Crick solving the structure of DNA p3 p3 p3 p3 p3 p3 p3
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
Boveri hypothesizing that chromosomes are the hereditary elements
p3 p3 p3 p3 p3 p3 p3 p3
e. All of the answer options are correct.
p3 p3 p3 p3 p3 p3
ANSWER: e p 3
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%. What is the
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
expected proportion of adenine?
p3 p3 p3 p3
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b p 3
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence in the
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
other strand must be
p3 p3 p3 p3
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b p 3
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e p 3
5. Which of the following is/are TRUE about genes?
p3 p3 p3 p3 p3 p3 p3
a. Genes are located on chromosomes. p3 p3 p3 p3
b. Genes come in variants known as alleles.
p3 p3 p3 p3 p3 p3
c. Genes usually encode protein products.
p3 p3 p3 p3
d. All of the answer options are correct.
p3 p3 p3 p3 p3 p3
e. None of the answer options is correct.
p3 p3 p3 p3 p3 p3
ANSWER: d p 3
1| P a g e
p3 p3 p3 p3
, Test Bank - Introduction to Genetic Analysis, 12th Edition (Griffiths, 2021)
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
in common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. less DNA than common-mouse cells.
p3 p3 p3 p3
b. smaller genomes than common-mouse cells. p3 p3 p3 p3
c. fewer DNA molecules than common-mouse cells.
p3 p3 p3 p3 p3
d. fewer genes than common-mouse cells.
p3 p3 p3 p3
e. fewer sets of chromosomes than common-mouse cells.
p3 p3 p3 p3 p3 p3
ANSWER: c p 3
7. Which of the following is a component of DNA?
p3 p3 p3 p3 p3 p3 p3 p3
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d p 3
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. It is a double-helical structure.
p3 p3 p3 p3
b. Sugar–phosphate backbone is always toward the outside of the DNA. p3 p3 p3 p3 p3 p3 p3 p3 p3
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
d. There are four types of nitrogenous bases.
p3 p3 p3 p3 p3 p3
e. All of the answer options are correct.
p3 p3 p3 p3 p3 p3
ANSWER: e p 3
9. Which of the following is a CORRECT representation of the central dogma?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. RNA → DNA → protein p3 p3 p3 p3
b. protein → DNA → RNA p3 p3 p3 p3
c. DNA → RNA → protein p3 p3 p3 p3
d. DNA → protein → DNA p3 p3 p3 p3
e. None of the answer options is correct.
p3 p3 p3 p3 p3 p3
ANSWER: c p 3
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
produced by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
mutation most likely taken place?
p3 p3 p3 p3 p3
a. in Cindy's gametes
p3 p3
b. in the cells that should normally have given rise to Cindy's tail
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
d. in all of Cindy's cells (including her gametes)
p3 p3 p3 p3 p3 p3 p3
e. in a gamete of one of Cindy's parents
p3 p3 p3 p3 p3 p3 p3
ANSWER: a p 3
11. Which of the following features makes a species suitable as a model organism?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
2| P a g e
p3 p3 p3 p3
p3
Introduction to Genetic Analysis
p3 p3 p3
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
12th Edition
p3
,Table of Contents
p3 p3
Chapter 01 The Genetics Revolution
p3 p3 p3 p3 1
Chapter 02 Single Gene Inheritance
p3 p3 p3 p3 6
Chapter 03 Independent Assortment of Genes
p3 p3 p3 p3 p3 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
p3 p3 p3 p3 p3 p3 43
Chapter 05 Gene Interaction
p3 p3 p3 63
Chapter 06 The Genetics of Bacteria and Their Viruses
p3 p3 p3 p3 p3 p3 p3 p3 84
Chapter 07 DNA Structure and Replication
p3 p3 p3 p3 p3 104
Chapter 08 RNA Transcription Processing and Decay
p3 p3 p3 p3 p3 p3 117
Chapter 09 Proteins and Their Synthesis
p3 p3 p3 p3 p3 130
Chapter 10 Gene Isolation and Manipulation
p3 p3 p3 p3 p3 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
p3 p3 p3 p3 p3 p3 p3 175
Chapter 13 The Genetic Control of Development
p3 p3 p3 p3 p3 p3 184
Chapter 14 Genomes and Genomics
p3 p3 p3 p3 192
Chapter 15 DNA Damage Repair and Recombination
p3 p3 p3 p3 p3 p3 197
Chapter 16 The Dynamic Genome Transposable Elements
p3 p3 p3 p3 p3 p3 216
Chapter 17 Large Scale Chromosomal Changes
p3 p3 p3 p3 p3 225
Chapter 18 Population Genetics
p3 p3 p3 243
Chapter 19 The Inheritance of Complex Traits
p3 p3 p3 p3 p3 p3 258
Chapter 20 Evolution of Genes and Traits
p3 p3 p3 p3 p3 p3 270
, Test Bank - Introduction to Genetic Analysis, 12th Edition (Griffiths, 2021)
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
Chapter 01: The Genetics Revolution
p3 p3 p3 p3
1. The early 1900s was an important period for genetics due to which of the following major events?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. the rediscovery of Gregor Mendel's scientific findings
p3 p3 p3 p3 p3 p3
b. Watson and Crick solving the structure of DNA p3 p3 p3 p3 p3 p3 p3
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
Boveri hypothesizing that chromosomes are the hereditary elements
p3 p3 p3 p3 p3 p3 p3 p3
e. All of the answer options are correct.
p3 p3 p3 p3 p3 p3
ANSWER: e p 3
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%. What is the
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
expected proportion of adenine?
p3 p3 p3 p3
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b p 3
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence in the
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
other strand must be
p3 p3 p3 p3
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b p 3
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e p 3
5. Which of the following is/are TRUE about genes?
p3 p3 p3 p3 p3 p3 p3
a. Genes are located on chromosomes. p3 p3 p3 p3
b. Genes come in variants known as alleles.
p3 p3 p3 p3 p3 p3
c. Genes usually encode protein products.
p3 p3 p3 p3
d. All of the answer options are correct.
p3 p3 p3 p3 p3 p3
e. None of the answer options is correct.
p3 p3 p3 p3 p3 p3
ANSWER: d p 3
1| P a g e
p3 p3 p3 p3
, Test Bank - Introduction to Genetic Analysis, 12th Edition (Griffiths, 2021)
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
in common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. less DNA than common-mouse cells.
p3 p3 p3 p3
b. smaller genomes than common-mouse cells. p3 p3 p3 p3
c. fewer DNA molecules than common-mouse cells.
p3 p3 p3 p3 p3
d. fewer genes than common-mouse cells.
p3 p3 p3 p3
e. fewer sets of chromosomes than common-mouse cells.
p3 p3 p3 p3 p3 p3
ANSWER: c p 3
7. Which of the following is a component of DNA?
p3 p3 p3 p3 p3 p3 p3 p3
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d p 3
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. It is a double-helical structure.
p3 p3 p3 p3
b. Sugar–phosphate backbone is always toward the outside of the DNA. p3 p3 p3 p3 p3 p3 p3 p3 p3
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
d. There are four types of nitrogenous bases.
p3 p3 p3 p3 p3 p3
e. All of the answer options are correct.
p3 p3 p3 p3 p3 p3
ANSWER: e p 3
9. Which of the following is a CORRECT representation of the central dogma?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
a. RNA → DNA → protein p3 p3 p3 p3
b. protein → DNA → RNA p3 p3 p3 p3
c. DNA → RNA → protein p3 p3 p3 p3
d. DNA → protein → DNA p3 p3 p3 p3
e. None of the answer options is correct.
p3 p3 p3 p3 p3 p3
ANSWER: c p 3
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
produced by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
mutation most likely taken place?
p3 p3 p3 p3 p3
a. in Cindy's gametes
p3 p3
b. in the cells that should normally have given rise to Cindy's tail
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
d. in all of Cindy's cells (including her gametes)
p3 p3 p3 p3 p3 p3 p3
e. in a gamete of one of Cindy's parents
p3 p3 p3 p3 p3 p3 p3
ANSWER: a p 3
11. Which of the following features makes a species suitable as a model organism?
p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3 p3
2| P a g e
p3 p3 p3 p3
