,TABLE OF CONTENT
m m
1. Microbial Life: Origin & Discovery
m m m m
2. Observing the Microbial Cell m m m
3. Cell Structure and Function
m m m
4. Bacterial Culture, Growth, and Development
m m m m
5. Environmental Influences and Control of Microbial Growth m m m m m m
6. Viruses
7. Genomes and Chromosomes m m
8. Transcription, Translation, and Protein Processing m m m m
9. Genetic Change and Genome Evolution
m m m m
10. Molecular Regulation m
11. Viral Molecular Biology
m m
12. Molecular Complexity and Synthetic Biology m m m m
13. Energetics and Catabolism m m
14. Electron Flow in Organotrophy, Lithotrophy, and Phototrophy
m m m m m m
15. Biosynthesis
16. Food and Industrial Microbiology
m m m
17. Origins and Evolution m m
18. Bacterial Diversity m
19. Archaeal Diversity m
20. Eukaryotic Diversity m
21. Microbial Ecology m
22. Element Cycles and Environmental Microbiology
m m m m
23. The Human Microbiome and Innate Immunity
m m m m m
24. The Adaptive Immune Response
m m m
25. Pathogenesis
26. Microbial Disease m
27. Antimicrobial Therapy and Discovery m m m
28. Clinical Microbiology and Epidemiology
m m m
,Microbiology An Evolving Science, 3rd Edition, John Foster & Joan Slonczewski Chapter
m m m m m m m m m m m
1-28
m
CHAPTER 1: Microbial Life: Origin and Discovery
m m m m m m
MULTIPLE CHOICEm
1. Viruses are: m
a. infectious agents that infect multi-cellular organisms m m m m m
b. noncellular particles that take over the metabolism of a cell to generate more
m m m m m m m m m m m m
virus particles
m m
c. pathogens that replicate in complex growth media m m m m m m
d. cellular particles that belong to the archaea domain m m m m m m m
e. microbes that consist of lipid membrane enclosed genomes m m m m m m m
Answer: B DIF: m Easy REF: 1.1 m TOP: I.A | I.B m m m
MSC: Rememberingm
2. Analysis of DNA sequences reveals:
m m m m
a. the ancient convergence of two cell types, i.e., prokaryotes and eukaryotes
m m m m m m m m m m
b. prokaryotes and eukaryotes evolved from a common ancestral cell m m m m m m m m
c. that bacteria share common ancestor with archaea, but not with eukarya
m m m m m m m m m m
d. prokaryotes are cells with a nucleus m m m m m
e. the genome of Haemophilus influenzae has about 2 billion base pairs
m m m m m m m m m m
Answer: B DIF: m Easy REF: 1.1 m TOP: I.A | I.B m m m
MSC: Rememberingm
3. Which of these groups are considered to be microbes but NOT considered to be cells?
m m m m m m m m m m m m m m
a. viruses d. protists m m
b. bacteria e. filamentous fungi m m m
c. archaea
Answer: A DIF: m Easy REF: 1.1 m TOP: I.A.i m
MSC: Rememberingm
4. A microbe is commonly defined as:
m m m m m
a. a virus that requires a microscope to be seen
m m m m m m m m
b. a bacterium that requires a microscope to be seen
m m m m m m m m
c. a single-cellular prokaryote that requires a microscope to be
m m m m m m m m
seenm
d. a multicellular eukaryote that requires a microscope to be seen
m m m m m m m m m
e. a living organism that requires a microscope to be seen
m m m m m m m m m
Answer: E DIF: m Easy REF: 1.1 m TOP: I.A.i | I.A.ii
m m m
MSC: Remembering
m m
5. Which one of the following statements regarding microbial cells is NOT true?
m m m m m m m m m m m
a. Microbial cells acquire food, gain energy to build themselves, and respond to
m m m m m m m m m m m
environmental change.
m m
, b. Most single-celled organisms require a microscope to render them visible, but
m m m m m m m m m m
some
m
bacterial cells are large enough to be seen with naked eyes.
m m m m m m m m m m
c. Microbes function as individual entities. m m m m
d. Many microbes form complex multicellular assemblages.
m m m m m
e. Viruses are not considered as microbial cells.
m m m m m m
Answer: C DIF: m Easy REF: 1.1 m TOP: I.A.i | I.A.ii
m m m
MSC: Remembering
m m
6. Which of the following statements is FALSE?
m m m m m m
a. A genome is the total genetic information contained in an organism’s chromosomal DNA.
m m m m m m m m m m m m
b. If a microbe’s genome includes genes for nitrogenase, that microbe probably can fix
m m m m m m m m m m m m
nitrogen.
m
c. By comparing DNA sequences of different organisms, we can figure out how closely
m m m m m m m m m m m m
related they are.
m m m
d. Fred Sanger developed the first applicable DNA sequencing method.
m m m m m m m m
e. Fred Sanger completed the sequences of Haemophilus influenzae.
m m m m m m m
Answer: E DIF: m Easy REF: 1.1 m TOP: I.B m
MSC: Remembering
m
7. The first cellular genomes to be sequenced were those of:
m m m m m m m m m
a. humans d. prions
b. bacteria e. fungi
c. viruses
Answer: B m DIF: Easy REF: 1.1 m TOP:
mI.B.i
MSC: Remembering
m
8. The environment of early Earth may have contained all of the following EXCEPT:
m m m m m m m m m m m m
a. ferrous iron m d. oxygen m m
b. methane e. hydrogen gas m m m
c. ammonia
Answer: D m DIF: Easy REF: Special Topic 1.1 m m m
TOP: II.D
m m MSC: Remembering m
9. The development of the theory of the ―RNA world‖ resulted from the discovery of:
m m m m m m m m m m m m m
a. archaea d. ribozymes m m
b. prions e. endosymbionts m m
c. bacteria
Answer: D m DIF: Medium REF: Special Topic 1.1 m m m
TOP: II.D
m m MSC: Remembering m
10. Which microbes may resemble those of the earliest life forms?
m m m m m m m m m
a. archaea d. cyanobacteria m m
b. photosynthetic algae e. protists m m m
c. viruses
Answer: A m DIF: Medium REF: Special Topic 1.1 m m m
TOP: II.D
m m MSC: Remembering m
11. Early metabolism may have been catalyzed by:
m m m m m m
a. DNA d. m m amino acids m