CPIA 2026/2027 QUESTIONS AND ANSWERS GUARANTEE
A+
✔✔What information must be provided in the report for deficiencies identified during the
IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant deficiencies,
and a description of minor deficiencies.
B. A reasonable and specific plan for correcting significant and minor deficiencies and a
schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and the
institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the corrections
and the IACUC members in charge of verifying the corrections. - ✔✔B. A reasonable
and specific plan for correcting significant and minor deficiencies and a schedule for
completing the corrective actions.
✔✔Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding. - ✔✔D. Institutions that accept PHS funding.
✔✔The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review. - ✔✔C. Replacement, reduction, and refinement.
✔✔What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing
equipment. - ✔✔B. Provides assistance with alternatives and database searches.
✔✔Which agency requires an annual report of the number of animals used by
pain/distress category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
D. United States Department of Agriculture - ✔✔D. United States Department of
Agriculture
✔✔Regarding studies with infectious agents in animals, as the BSL and ABSL number
increases from 1 to 4, what happens to the containment and safeguard practices?
,A. They become less important.
B. They become less stringent.
C. They become more vague.
D. They become more stringent. - ✔✔D. They become more stringent.
✔✔U.S. Government Principles on the Use of Animals in Research state that:
A. Relief of pain should be provided for vertebrate animals except for birds, mice and
rats.
B. Animals will show evidence of pain if a procedure causes them pain.
C. Pain is perceived differently by animals than by humans.
D. Procedures that are painful to humans should be assumed to cause pain in animals
unless there is evidence to the contrary. - ✔✔D. Procedures that are painful to humans
should be assumed to cause pain in animals unless there is evidence to the contrary.
✔✔Which of the statements below about the responsibility and authority of the
Institutional Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the animal
care and use program.
B. If the IO is not the institution's Chief Executive Officer, then the CEO must delegate
IO authority to that person in writing.
C. The IO may reinstate an animal activity that was previously suspended by the
IACUC.
D. The IO may suspend an animal activity that was previously approved by the IACUC.
- ✔✔C. The IO may reinstate an animal activity that was previously suspended by the
IACUC.
✔✔PHS policy states that the OLAW requires assurance renewal every:
a) three years
b) up to five years
c) four years
d) depends on the institution and program size - ✔✔b) up to five years
✔✔The guide incorporated two must to Diaster Planning and Emergency Prepardness
which involved:
a) triage plans for personnel and animals
b) emergency contacts for all researchers and staff
c) plans include satellite facilities
d) corrdinated by the institutional official
e) provisions on euthanasia
The correct answer is:
1. a and e
2. a and d
3. c and e
4. All the above - ✔✔3. c and e
,✔✔For the VA semiannual program review and facility inspection report, which of the
following need not be included:
a. Date of the review/isnpection
b. Names of individuals responsible for corrective actions
c. The signatures of the majority of the voting members
d. The timeline for the corrective actions
e. The reason for the deficiency - ✔✔c. The signatures of the majority of the voting
members
✔✔According to the Guide, who can conduct Post-Approval Monitoring (PAM)?
a) IACUC
b) veterinarians
c) animal care personnel
d) compliance staff
e) all the above - ✔✔e) all the above
✔✔According to PHS, awardee institutions shall maintain good recordkeeping. Which
one is not a recordkeeping requirement?
a) a copy of the Assurance approved by PHS
b) minutes of IACUC meetings
c) records of accrediting body determinations
d) records and proposals and applications and propose significant changes, IACUC
reports and recommendations
e) records of semiannual IACUC reports to IO (including minority views)
d) all the above
e) none of the above - ✔✔e) none of the above
✔✔The 8th addition of the guide incorporated new additions to the guide: IACUC,
IACUC Training, Personnel Security, Investigating and Reporting Animal Welfare
Concerns, Veterinary Clinical Care Management, Drug Storage and Control. According
to the Guide, what item not a requirement for IACUC members:
a) Formal orientation to the institution's program
b) Training by a certified veterinarian on all procedures involving animals
c) Training on how to review protocols as well as evaluate the program
d) Training on how to inspect facilities and labs where animal use or housing occurs
e) Training on legislation, regulations, guidelines, and policies - ✔✔b) Training by a
certified veterinarian on all procedures involving animals
✔✔Which of the following is not required for IACUC membership according to the Ag
Guide:
a. veterinarian with training or experience in laboratory animal science and medicine
b. scientist with training or experience in agricultural animals
c. a person whose primary concerns are in an area outside of science
d. a person who is not affiliated with the institution - ✔✔a. veterinarian with training or
experience in laboratory animal science and medicine
, ✔✔USDA Regulations require the following IACUC members:
1. Veterinarian, chair, nonaffiliated
2. Veterinarian, chair, scientist
3. Veterinarian, nonaffiliated, scientist
4. Veterinarian, nonaffiliated, nonscientist - ✔✔1. Veterinarian, chair, nonaffiliated
✔✔PHS Policy requires the following IACUC members:
1. Veterinarian, chair, nonscientist, nonaffiliated
2. Veterinarian, chair, nonaffiliated, scientist
3. Veterinarian, nonaffiliated, scientist, nonscientist
4. Veterinarian, nonaffiliated, nonscientist, statistician - ✔✔3. Veterinarian, nonaffiliated,
scientist, nonscientist
✔✔PHS and AWRs state that all records should be kept for a minimum of:
a) indefinate
b) 1-2 years
c) 3 years
d) non of the above - ✔✔c) 3 years
✔✔PHS institutional Assurance is approve up to ___ years where as USDA registration
is updated every ___ years:
a) 3yrs PHS and 5 years USDA
b) up to 5 years for PHS and 3 years FOR USDA
c) up to 5 years for both
d) 3 years for both - ✔✔b) up to 5 years for PHS and 3 years FOR USDA
✔✔Which is not required when filing a PHS Institutional Assurance:
a) dates of facility inspections
b) IACUC member roster
c) Number of covered species used annually
d) Lines of authority
e) species housed and average daily inventory by species - ✔✔c) Number of covered
species used annually
✔✔If the institution is PHS assured and is not AAALAC accredited, what must be
included in the annual report to OLAW?
a) The IACUC minutes
b) The intituional officals assurance statement
c) Semiannual IACUC report
d) none of the above - ✔✔c) Semiannual IACUC report
A+
✔✔What information must be provided in the report for deficiencies identified during the
IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant deficiencies,
and a description of minor deficiencies.
B. A reasonable and specific plan for correcting significant and minor deficiencies and a
schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and the
institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the corrections
and the IACUC members in charge of verifying the corrections. - ✔✔B. A reasonable
and specific plan for correcting significant and minor deficiencies and a schedule for
completing the corrective actions.
✔✔Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding. - ✔✔D. Institutions that accept PHS funding.
✔✔The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review. - ✔✔C. Replacement, reduction, and refinement.
✔✔What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing
equipment. - ✔✔B. Provides assistance with alternatives and database searches.
✔✔Which agency requires an annual report of the number of animals used by
pain/distress category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
D. United States Department of Agriculture - ✔✔D. United States Department of
Agriculture
✔✔Regarding studies with infectious agents in animals, as the BSL and ABSL number
increases from 1 to 4, what happens to the containment and safeguard practices?
,A. They become less important.
B. They become less stringent.
C. They become more vague.
D. They become more stringent. - ✔✔D. They become more stringent.
✔✔U.S. Government Principles on the Use of Animals in Research state that:
A. Relief of pain should be provided for vertebrate animals except for birds, mice and
rats.
B. Animals will show evidence of pain if a procedure causes them pain.
C. Pain is perceived differently by animals than by humans.
D. Procedures that are painful to humans should be assumed to cause pain in animals
unless there is evidence to the contrary. - ✔✔D. Procedures that are painful to humans
should be assumed to cause pain in animals unless there is evidence to the contrary.
✔✔Which of the statements below about the responsibility and authority of the
Institutional Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the animal
care and use program.
B. If the IO is not the institution's Chief Executive Officer, then the CEO must delegate
IO authority to that person in writing.
C. The IO may reinstate an animal activity that was previously suspended by the
IACUC.
D. The IO may suspend an animal activity that was previously approved by the IACUC.
- ✔✔C. The IO may reinstate an animal activity that was previously suspended by the
IACUC.
✔✔PHS policy states that the OLAW requires assurance renewal every:
a) three years
b) up to five years
c) four years
d) depends on the institution and program size - ✔✔b) up to five years
✔✔The guide incorporated two must to Diaster Planning and Emergency Prepardness
which involved:
a) triage plans for personnel and animals
b) emergency contacts for all researchers and staff
c) plans include satellite facilities
d) corrdinated by the institutional official
e) provisions on euthanasia
The correct answer is:
1. a and e
2. a and d
3. c and e
4. All the above - ✔✔3. c and e
,✔✔For the VA semiannual program review and facility inspection report, which of the
following need not be included:
a. Date of the review/isnpection
b. Names of individuals responsible for corrective actions
c. The signatures of the majority of the voting members
d. The timeline for the corrective actions
e. The reason for the deficiency - ✔✔c. The signatures of the majority of the voting
members
✔✔According to the Guide, who can conduct Post-Approval Monitoring (PAM)?
a) IACUC
b) veterinarians
c) animal care personnel
d) compliance staff
e) all the above - ✔✔e) all the above
✔✔According to PHS, awardee institutions shall maintain good recordkeeping. Which
one is not a recordkeeping requirement?
a) a copy of the Assurance approved by PHS
b) minutes of IACUC meetings
c) records of accrediting body determinations
d) records and proposals and applications and propose significant changes, IACUC
reports and recommendations
e) records of semiannual IACUC reports to IO (including minority views)
d) all the above
e) none of the above - ✔✔e) none of the above
✔✔The 8th addition of the guide incorporated new additions to the guide: IACUC,
IACUC Training, Personnel Security, Investigating and Reporting Animal Welfare
Concerns, Veterinary Clinical Care Management, Drug Storage and Control. According
to the Guide, what item not a requirement for IACUC members:
a) Formal orientation to the institution's program
b) Training by a certified veterinarian on all procedures involving animals
c) Training on how to review protocols as well as evaluate the program
d) Training on how to inspect facilities and labs where animal use or housing occurs
e) Training on legislation, regulations, guidelines, and policies - ✔✔b) Training by a
certified veterinarian on all procedures involving animals
✔✔Which of the following is not required for IACUC membership according to the Ag
Guide:
a. veterinarian with training or experience in laboratory animal science and medicine
b. scientist with training or experience in agricultural animals
c. a person whose primary concerns are in an area outside of science
d. a person who is not affiliated with the institution - ✔✔a. veterinarian with training or
experience in laboratory animal science and medicine
, ✔✔USDA Regulations require the following IACUC members:
1. Veterinarian, chair, nonaffiliated
2. Veterinarian, chair, scientist
3. Veterinarian, nonaffiliated, scientist
4. Veterinarian, nonaffiliated, nonscientist - ✔✔1. Veterinarian, chair, nonaffiliated
✔✔PHS Policy requires the following IACUC members:
1. Veterinarian, chair, nonscientist, nonaffiliated
2. Veterinarian, chair, nonaffiliated, scientist
3. Veterinarian, nonaffiliated, scientist, nonscientist
4. Veterinarian, nonaffiliated, nonscientist, statistician - ✔✔3. Veterinarian, nonaffiliated,
scientist, nonscientist
✔✔PHS and AWRs state that all records should be kept for a minimum of:
a) indefinate
b) 1-2 years
c) 3 years
d) non of the above - ✔✔c) 3 years
✔✔PHS institutional Assurance is approve up to ___ years where as USDA registration
is updated every ___ years:
a) 3yrs PHS and 5 years USDA
b) up to 5 years for PHS and 3 years FOR USDA
c) up to 5 years for both
d) 3 years for both - ✔✔b) up to 5 years for PHS and 3 years FOR USDA
✔✔Which is not required when filing a PHS Institutional Assurance:
a) dates of facility inspections
b) IACUC member roster
c) Number of covered species used annually
d) Lines of authority
e) species housed and average daily inventory by species - ✔✔c) Number of covered
species used annually
✔✔If the institution is PHS assured and is not AAALAC accredited, what must be
included in the annual report to OLAW?
a) The IACUC minutes
b) The intituional officals assurance statement
c) Semiannual IACUC report
d) none of the above - ✔✔c) Semiannual IACUC report
