NR 507 Edapt Unit 2 Hematological Disorders
1. what are four clinical characteristics of tachycardia (due to hypoxemia), pallor, dysp-
anemia? nea, and fatigue
2. which RBC indices measures the average mean corpuscular volume (MCV)
size of red blood cells?
3. anemia can be caused by ______, ______, excessive blood loss, impaired RBC production,
and ______. and increased RBC destruction
4. which anemia is considered a microcytic iron-deficiency anemia
anemia?
5. definition of anemia Anemia is a hematological disorder character-
ized by a reduction in the total number of circu-
lating red blood cells (RBCs) and/or a decrease
in hemoglobin (Hb) amount or function.
6. Complete blood count (CBC) compo-
nents that relate to RBCs and their pro-
duction
7. microcytic anemia MCV<80 fL
- RBCs are small
- iron-deficiency anemia
- sideroblastic anemia
- thalassemia
- anemia of chronic disease
8. normocytic anemia MCV 80-99 fL
- RBCs are normal in size
, NR 507 Edapt Unit 2 Hematological Disorders
- anemia of inflammation and chronic disease
- hereditary spherocytosis
- G6PD deficiency
- paroxysmal nocturnal hemoglobinuria
9. macrocytic anemia MCV > 100 fL
- RBCs are large
- B12 deficiency (pernicious anemia)
- folate deficiency
10. hypochromic anemia low MCHC
- RBCs have less hemoglobin than normal
- RBCs appear pale in color
11. normochromic normal MCHC
- RBCs have a normal amount of hemoglobin
- RBCs appear neither pale nor dark
12. hyperchromic high MCHC
- RBCs have more hemoglobin than normal
- RBCs appear a deeper hue of red than normal
13. clinical manifestations of anemia - severe fatigue
- pallor
- weakness
- dyspnea
- dizziness
Furthermore, the reduction in RBC level will de-
crease blood volume, activating the renin-an-
giotensin-aldosterone (RAA) system, which pro-
motes fluid retention and movement of intersti-
tial fluid into the capillaries. This will not only in-
, NR 507 Edapt Unit 2 Hematological Disorders
crease plasma volume, but also dilute the plas-
ma further. The dilute blood flows faster, which
creates a hyperdynamic state. This "stresses" the
cardiac system and can result in tachycardia or
even heart failure.
14. the terms normocytic, microcytic, and size
macrocytic characterizes red blood cells Terms that end with "-cytic" refer to cell size.
by their _______.
15. what symptoms reflect decreased tissue weakness, hypertension, fever, dizziness, and
oxygenation as an effect of anemia? dyspnea
16. true or false: false
identification of the type of anemia in- Determining both the size and color of RBCs is
volves an exemption of size of the red an important step in identifying the type and
blood cell only. source of anemia.
17. which anemia is a type of macrocytic vitamin B12 deficiency (pernicious anemia)
anemia?
18. which lab value indicates the patient's ferritin level
iron stores are depleted? A low ferritin level indicates that the patient's
iron stores are depleted.
19. which anemias can be categorized as mi- iron-deficiency anemia, sideroblastic anemia,
crocytic-hypochromic? and anemia of inflammation and chronic dis-
ease
20. what is the most common type of ane- iron-deficiency anemia
mia? IDA is the most common type of anemia world-
wide.
21.
1. what are four clinical characteristics of tachycardia (due to hypoxemia), pallor, dysp-
anemia? nea, and fatigue
2. which RBC indices measures the average mean corpuscular volume (MCV)
size of red blood cells?
3. anemia can be caused by ______, ______, excessive blood loss, impaired RBC production,
and ______. and increased RBC destruction
4. which anemia is considered a microcytic iron-deficiency anemia
anemia?
5. definition of anemia Anemia is a hematological disorder character-
ized by a reduction in the total number of circu-
lating red blood cells (RBCs) and/or a decrease
in hemoglobin (Hb) amount or function.
6. Complete blood count (CBC) compo-
nents that relate to RBCs and their pro-
duction
7. microcytic anemia MCV<80 fL
- RBCs are small
- iron-deficiency anemia
- sideroblastic anemia
- thalassemia
- anemia of chronic disease
8. normocytic anemia MCV 80-99 fL
- RBCs are normal in size
, NR 507 Edapt Unit 2 Hematological Disorders
- anemia of inflammation and chronic disease
- hereditary spherocytosis
- G6PD deficiency
- paroxysmal nocturnal hemoglobinuria
9. macrocytic anemia MCV > 100 fL
- RBCs are large
- B12 deficiency (pernicious anemia)
- folate deficiency
10. hypochromic anemia low MCHC
- RBCs have less hemoglobin than normal
- RBCs appear pale in color
11. normochromic normal MCHC
- RBCs have a normal amount of hemoglobin
- RBCs appear neither pale nor dark
12. hyperchromic high MCHC
- RBCs have more hemoglobin than normal
- RBCs appear a deeper hue of red than normal
13. clinical manifestations of anemia - severe fatigue
- pallor
- weakness
- dyspnea
- dizziness
Furthermore, the reduction in RBC level will de-
crease blood volume, activating the renin-an-
giotensin-aldosterone (RAA) system, which pro-
motes fluid retention and movement of intersti-
tial fluid into the capillaries. This will not only in-
, NR 507 Edapt Unit 2 Hematological Disorders
crease plasma volume, but also dilute the plas-
ma further. The dilute blood flows faster, which
creates a hyperdynamic state. This "stresses" the
cardiac system and can result in tachycardia or
even heart failure.
14. the terms normocytic, microcytic, and size
macrocytic characterizes red blood cells Terms that end with "-cytic" refer to cell size.
by their _______.
15. what symptoms reflect decreased tissue weakness, hypertension, fever, dizziness, and
oxygenation as an effect of anemia? dyspnea
16. true or false: false
identification of the type of anemia in- Determining both the size and color of RBCs is
volves an exemption of size of the red an important step in identifying the type and
blood cell only. source of anemia.
17. which anemia is a type of macrocytic vitamin B12 deficiency (pernicious anemia)
anemia?
18. which lab value indicates the patient's ferritin level
iron stores are depleted? A low ferritin level indicates that the patient's
iron stores are depleted.
19. which anemias can be categorized as mi- iron-deficiency anemia, sideroblastic anemia,
crocytic-hypochromic? and anemia of inflammation and chronic dis-
ease
20. what is the most common type of ane- iron-deficiency anemia
mia? IDA is the most common type of anemia world-
wide.
21.
