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Exam (elaborations)

GNRS 610-ADVANCED PATHO-EXAM 2| 2025 AZUSA PACIFIC UNIVERSITY|ACTUAL 150Qs&As|GRADED A+

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Conquer GNRS 610 Advanced Pathophysiology Exam 2 with this all-inclusive 2025 study guide from Azusa Pacific University! This resource features 150 verified questions and detailed answers covering the core second-half topics of the course. What's Inside: 150 Comprehensive Questions & Answers from the actual GNRS 610 Exam 2. Detailed Rationales that explain the "why" behind each answer for deeper learning. Extensive Topic Coverage: Immunology: Innate vs. Adaptive Immunity, Inflammatory Response, Cells (Neutrophils, Macrophages, Mast Cells), Complement System, Hypersensitivity (Types I-IV). Endocrine System: Hormone Regulation (RAAS, ADH), Pituitary, Thyroid (Graves', Hypothyroidism), Diabetes (DKA, HHNS), Adrenal Disorders. Hematology: Anemias (Microcytic, Macrocytic, Normocytic - Iron Deficiency, B12, Folate, Sickle Cell, Thalassemia), Leukemia, Lymphoma. Renal System: Acute Kidney Injury (Pre-renal, Intrarenal, Post-renal), Chronic Renal Failure, Glomerular Filtration Rate (GFR), Lab Values (BUN/Creatinine), UTIs. Clinical Application: Includes case studies and scenario-based questions to test your applied knowledge. Graded A+ material to ensure you are studying the most effective and high-yield content. Ideal for graduate nursing students at Azusa Pacific University and other programs. This is your essential tool for mastering complex pathophysiological concepts and excelling on the exam.

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Institution
GNRS 610-ADVANCED PATHO
Course
GNRS 610-ADVANCED PATHO

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Uploaded on
November 10, 2025
Number of pages
101
Written in
2025/2026
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Exam (elaborations)
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Questions & answers

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GNRS 610-ADVANCED PATHO-EXAM 2| 2025
AZUSA PACIFIC UNIVERSITY|ACTUAL
150Qs&As|GRADED A+

1. Describe the structure and function of deoxyribonucleic acid (DNA) -
..........ANSWER.......- 4 compents of DNA: sugar, phosphate and
nucleotide bases
-Sugar-phosphate backbone
-Nitrogen bases are steps
- 2 DNA strands make a pain


-adenine-- thymine
-Guanine-- cytosine


Function of deoxyribnucleic acid (DNA) in molecular inheritance -
..........ANSWER.......


Transcription - ..........ANSWER.......-Process of making mRNA
RNA- single stranded, has uracil instead of thymine
-mRNA made from a piece of DNA


Translation - ..........ANSWER.......

,2|Page


Functions of the endocrine system - ..........ANSWER.......1.
differentiation of the reproductive and central nervous systems in the
developing fetus
2. stimulation of sequential growth and development during childhood
and adolescence
3. Coordination of the male and female reproductive systems
(reproduction)
4. maintenance of an optimal internal environment through life
5. Initiation of corrective and adaptive responses when emergency
demands occur


Innate Immunity - ..........ANSWER.......-Defense mechanisms that are
present at birth and provide the initial nonspecific response to invasion
and injury
-includes natural barriers (first line of defense) and inflammation
(second line of defense)


Adaptive immunity - ..........ANSWER.......-immunity that develops over
the lifetime of the individual and provides long-term protection against
specific invaders
-"memory"
-third line of defense


Protein components of ADAPTIVE immunity - ..........ANSWER.......1.
Antibodies
2. Humoral immunity

,3|Page




Cellular component of ADAPTIVE immunity - ..........ANSWER.......1.
T-cells
-T-cytotoxic (CD-8)
-T-helper (CD-4)


2. B-cells
-plasma cells
-memory cells


3. Memory cells


Physical and Mechanical Barriers - ..........ANSWER.......-Epithelial cells
of the skin
-linings of the GI, GU and respiratory tract (mucous membranes)


Biochemical Barriers - ..........ANSWER.......-synthesize and secreted
substances meant to trap or destroy microorganisms derived from the
epithelial cells
-Mucus, perspiration, saliva, tears and earwax


Normal flora - ..........ANSWER.......-Microorganisms that reside in or on
the body without causing disease
- Skin and gut flora

, 4|Page


Inflammation - ..........ANSWER.......- Activated by any injury to
vascularized tissues
-When pathogen invasion or tissue damage occurs, inflammation is
initiated by guardian cells (mast cells, macrophages, and dendritic cells)


Inflammatory Response - ..........ANSWER.......1. Occurs in vascularized
tissues
2. Activation is rapid (within seconds) after damage occurs
3. Includes chemical, vascular and cellular components
4. Response is nonspecfic


-second line of defense


Protective functions of inflammation - ..........ANSWER.......1.
Prevention of infection and further damage caused by invading
microorganisms - exudates dilute toxins produced by bacteria and dying
cells
2. Preparation of injury for healing and repair- removal of bacteria,
micro-organisms, dead cells and debris
3. Facilitation of the development of adaptive immunity


Cellular components of the inflammatory response -
..........ANSWER.......1. Mast Cells
2. Granulocytes: neutrophils, basophils, eosinophils
3. Macrophages

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