NUR 641E PATHO
Ace Your NUR 641E Exam: The Ultimate Pathophysiology
& Pharmacology Solution Pack for Nurse Educators
What is prodrug? - Answer- biologically inactive compound which can be metabolized in
the body to produce a drug
Prednisone is an example of? - Answer- Prodrug
active drug--> prednisolone; anti-inflammatory
What is bioavailability? - Answer- the proportion of a drug or other substance which enters
the circulation when introduced into the body and so is able to have an active effect
What is pharmacokinetics? - Answer- the branch of pharmacology concerned with the
movement of drugs within the body
What is the cytochrome P450 system? - Answer- A super family of enzymes, primarily
found in the liver, that plays a crucial role in metabolizing drugs, chemicals, and
endogenous substances, converting them into more water-soluble forms of excretion
Is Clopidogrel is prodrug? - Answer- yes
Where is plavix activated? - Answer- This drug must be activated by hepatic CYP2C19
metabolism
What is half life? - Answer- The time it takes for the amount of a drug's active substance in
your body to reduce by half
, NUR 641E PATHO
What is a steady state of a drug? - Answer- This is when the rate of drug availability in the
body and elimination from the body equal one another
What are the 7 routes of drug administration? - Answer- Intravenous
intramuscular
subcutaneous
rectal
vaginal
inhaled
topical
What is the onset of intravenous administration? - Answer- 20-40 seconds
What is the onset of IM administration? - Answer- 5 to 30 minutes
What is the onset of sub-Q administration? - Answer- 3 to 5 minutes
full effect up to 30 to 45 minutes
Onset of rectal administration? - Answer- about 5 minutes
Onset of vaginal adminsitration? - Answer- 15 to 30 minutes
What is topical administration onset time? - Answer- rapid onset
5 to 10 minutes
What are the risk factors for a CVA? - Answer- Age
Gender
Family history
Ace Your NUR 641E Exam: The Ultimate Pathophysiology
& Pharmacology Solution Pack for Nurse Educators
What is prodrug? - Answer- biologically inactive compound which can be metabolized in
the body to produce a drug
Prednisone is an example of? - Answer- Prodrug
active drug--> prednisolone; anti-inflammatory
What is bioavailability? - Answer- the proportion of a drug or other substance which enters
the circulation when introduced into the body and so is able to have an active effect
What is pharmacokinetics? - Answer- the branch of pharmacology concerned with the
movement of drugs within the body
What is the cytochrome P450 system? - Answer- A super family of enzymes, primarily
found in the liver, that plays a crucial role in metabolizing drugs, chemicals, and
endogenous substances, converting them into more water-soluble forms of excretion
Is Clopidogrel is prodrug? - Answer- yes
Where is plavix activated? - Answer- This drug must be activated by hepatic CYP2C19
metabolism
What is half life? - Answer- The time it takes for the amount of a drug's active substance in
your body to reduce by half
, NUR 641E PATHO
What is a steady state of a drug? - Answer- This is when the rate of drug availability in the
body and elimination from the body equal one another
What are the 7 routes of drug administration? - Answer- Intravenous
intramuscular
subcutaneous
rectal
vaginal
inhaled
topical
What is the onset of intravenous administration? - Answer- 20-40 seconds
What is the onset of IM administration? - Answer- 5 to 30 minutes
What is the onset of sub-Q administration? - Answer- 3 to 5 minutes
full effect up to 30 to 45 minutes
Onset of rectal administration? - Answer- about 5 minutes
Onset of vaginal adminsitration? - Answer- 15 to 30 minutes
What is topical administration onset time? - Answer- rapid onset
5 to 10 minutes
What are the risk factors for a CVA? - Answer- Age
Gender
Family history
