APMLE Part 2 Metabolic Diseases of Muscle and Bone:
Infectious Arthritis Final
Acromegaly Correct Answers caused by hypersecretion of GH
in adults
Acromegaly Correct Answers radiographs of hands and feet
show widened joint spaces, overgrowth of terminal tufts,
enlargement of sesamoids and soft tissue thickeing
Acromegaly Correct Answers results in periosteal and endosteal
bone formation, thickening and ossification of cartilage,
thickening of soft tissue and organomegaly
Acute osteoporosis Correct Answers Shows patchy moth eaten
appearance of bone with intracortical tunneling
Chronic osteoporosis Correct Answers Thinnig of bone cortex,
decrease in trabeculae will give overal decrease in bone density
Fibromyalgia Correct Answers 90% female, 20 to 60 years
Fibromyalgia Correct Answers a/w irritable bowl syndrome,
tension headaches, paresthesias, sensation of swollen hands
Fibromyalgia Correct Answers Clinical examination makes the
diagnosis; there are no exclusion lab tests
Fibromyalgia Correct Answers Fatigue is felt to be due to sleep
disturbance
, Fibromyalgia Correct Answers presence of 11 or more of 18
tender point sites
Fibromyalgia Correct Answers Treatment: patient education,
tricyclic antidepressants (Amitriptyline or Pregabalin), sleep
modification
Fibromyalgia Correct Answers unknown etiology, poorly
understood disease process that is non inflammatory in nature,
labs normal
Fibromyalgia Correct Answers widespread pain above and
below waste on both sides of body a/w stiffness, fatigue, sleep
disturbances
Focal osteoporosis Correct Answers caues include disuse,
osteomyelitis, RSD, tumor
Generalized osteoperosis Correct Answers causes include
aging, steroids, heparin, malnutrtion, hyperparathyroidism and
other endocrine abnormalities, oseogenesis imperfecta
Generalized osteoporosis Correct Answers accelerated in
women because decreased estrogen production following
menopause
Gonococcal Arthritis Correct Answers Gram negative
intracellular and extracellular diplococci producing septic
arthritis to hands, wrists, elbows, ankles and rarely the axial
skeleton
Infectious Arthritis Final
Acromegaly Correct Answers caused by hypersecretion of GH
in adults
Acromegaly Correct Answers radiographs of hands and feet
show widened joint spaces, overgrowth of terminal tufts,
enlargement of sesamoids and soft tissue thickeing
Acromegaly Correct Answers results in periosteal and endosteal
bone formation, thickening and ossification of cartilage,
thickening of soft tissue and organomegaly
Acute osteoporosis Correct Answers Shows patchy moth eaten
appearance of bone with intracortical tunneling
Chronic osteoporosis Correct Answers Thinnig of bone cortex,
decrease in trabeculae will give overal decrease in bone density
Fibromyalgia Correct Answers 90% female, 20 to 60 years
Fibromyalgia Correct Answers a/w irritable bowl syndrome,
tension headaches, paresthesias, sensation of swollen hands
Fibromyalgia Correct Answers Clinical examination makes the
diagnosis; there are no exclusion lab tests
Fibromyalgia Correct Answers Fatigue is felt to be due to sleep
disturbance
, Fibromyalgia Correct Answers presence of 11 or more of 18
tender point sites
Fibromyalgia Correct Answers Treatment: patient education,
tricyclic antidepressants (Amitriptyline or Pregabalin), sleep
modification
Fibromyalgia Correct Answers unknown etiology, poorly
understood disease process that is non inflammatory in nature,
labs normal
Fibromyalgia Correct Answers widespread pain above and
below waste on both sides of body a/w stiffness, fatigue, sleep
disturbances
Focal osteoporosis Correct Answers caues include disuse,
osteomyelitis, RSD, tumor
Generalized osteoperosis Correct Answers causes include
aging, steroids, heparin, malnutrtion, hyperparathyroidism and
other endocrine abnormalities, oseogenesis imperfecta
Generalized osteoporosis Correct Answers accelerated in
women because decreased estrogen production following
menopause
Gonococcal Arthritis Correct Answers Gram negative
intracellular and extracellular diplococci producing septic
arthritis to hands, wrists, elbows, ankles and rarely the axial
skeleton
