FINAL EXAM
gram positive bacteria
staph
strep
enterococcus
- everything else is gram negative
penicillins
MOA: inhibit bacterial wall synthesis by binding to and activating
enzymes that are essential for cell wall function
effective against gram positive bacteria
- strep throat
- ear infections
- syphillis
cephalosporins
MOA: inhibit cell wall synthesis
broad spectrum, effective against pos and neg bacteria, later generations
are more effective against gram neg
treat respiratory infections, UTIs, skin infections, bacterial meningitis,
pneumonia
cephalosporin generations
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, NURS 5433 FNP II LATEST
FINAL EXAM
1 - cephalexin
2 - cefuroxime
3 - ceftriaxone
4 - cefepime
macrolides
MOA: inhibit bacterial protein synthesis
effective against primarily gram pos but some gram neg
erythromycin, azithromycin, clarithromycin
treat respiratory infections, bronchitis, pna, skin infections, STIs
flouroquinolones
MOA: inhibit bacterial DNA synthesis
broad spectrum +/-
ciprofloxacin, levofloxacin, moxifloxacin
UTIs, GI infections, respiratory infections, skin infections
Risk of tendon rupture! Last resort abx
tetracyclines
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, NURS 5433 FNP II LATEST
FINAL EXAM
MOA: inhibit bacterial synthesis
broad spectrum +/-
tetracycline, doxycycline, minocycline
acne, respiratory infections, lyme, rocky mountain spotted fever, STIs
don't use in kids <8 y.o. unless RMSF
aminoglycosides
MOA: inhibit bacterial protein synthesis
gram negative bacteria
tobramicin, gentamicin, amikacin
treat sepsis, pna, UTIs, often in combo with another med
risk of ototoxicity, nephrotoxicity, neuromuscular blockade
sulfonamides
MOA: inhibits synthesis of folic acid in bacteria
gram + and some gram neg
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, NURS 5433 FNP II LATEST
FINAL EXAM
bactrim, sulfamethoxazole
UTIs, ear infections, PNA
Live attenuated vaccines
MMR, varicella, nasal flu, rotavirus, yellow fever, smallpox
can cause fever and rash - normal!
must be given on the same day or at least 4 weeks apart, too close
together can interfere with effectiveness
AVOID in pregnancy and immunocompromised
do not give before 1 year old
When do you start giving flu vaccine?
6 months old
Do you vaccinate if the child is ill or febrile?
Yes
kawasaki disease
acute inflammatory condition that affects kids <5 y.o, inflammation of
blood vessels, can lead to heart problems
s/s:
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