Test Bank For Clayton's Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz ( ) / 9780323796309 / Chapter 1-48 / Complete Questions and Answers A+

Test Bank For Clayton’s Basic Pharmacology for Nurses 19th EditionB
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y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Comple
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,Chapter 01: Drug Definitions, Standards, and Information Sources Willihngan
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z: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE tg




1. Which name identifies a drug listed by the US Food an
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dDrug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C tg


The official name is the name under which a drug is listed
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by the FDA. The brand name, or trademark, is the name giv
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en to a drug by its manufacturer. The nonproprietary, or gen
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eric, name is provided by the United States Adopted Names
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Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 tg tg tg tg


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Car
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eEnvironment TOP: Nursing Process Step: Assessment
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CON: tg


Patient Education tg




2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN &International Drug Names
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b. Natural Medicines Comprehensive Database tg tg tg


c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts tg tg




ANS: C tg


United States Pharmacopoeia/National Formulary contains information specific to nutritional
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supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include nut
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ritional supplements. Natural Medicines Comprehensive Database contains
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evidence-
based information on herbal medicines and herbal combination products; it does notinclude inf
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ormation specific to nutritional supplements. Drug Interaction Facts contains comprehensive
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ginformation on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 tg tg t g tg


OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
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grity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons tg tg tg

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editio
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b. Drug Interaction Facts tg tg


c. Handbook on Injectable Drugs tg tg tg


d. Martindale—The Complete Drug Reference tg tg tg




ANS: A tg


Drug Facts and Comparisons contains drug monographs that describe all drugs in at
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herapeutic class. Monographs are formatted as tables to allow comparison of similarpr
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oducts, brand names, manufacturers, cost indices, and available dosage forms Online
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version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 tg tg t g tg tg tg


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-
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entity drug availablein the United States and describes therapeutic uses of drugs, including a
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pproved and unapproved uses? tg tg tg


a. Martindale: The Complete Drug Reference tg tg tg tg


b. AHFS Drug Information tg tg


c. Drug Reference tg


d. Drug Facts and Comparisons tg tg tg




ANS: B tg


AHFS Drug Information contains monographs about virtually every single-
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entity drug available in the United States and describes therapeutic uses of drugs, including ap
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proved andunapproved uses. tg tg tg




DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 tg tg t g tg tg tg


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
t g CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a sta
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ndard, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index tg tg


b. American Hospital Formulary tg tg


c. DailyMed
d. Drug Reference tg




ANS: C tg


DailyMed makes available to healthcare providers and the public a standard, comprehensive,
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up-to-
date look up and downloadable resource about medicines. The American Drug Index isnot ap
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propriate for patient use. The American Hospital Formulary is not appropriate for patient us
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e. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 tg tg t g tg tg tg tg


OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
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grity
TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) tg tg tg tg tg tg


b. Durham Humphrey Amendment (1952) tg tg tg

, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editio
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c. Controlled Substances Act (1970) tg tg tg


d. Kefauver Harris Drug Amendment (1962) tg tg tg tg




ANS: A tg


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the saf
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ety of all drugs before marketing. Later amendments and acts helped tighten FDA control an
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d ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that can
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not be used safely without medical supervision and restricts their sale to prescription by a lic
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ensed practitioner. The Controlled Substances Act addresses only controlled substances andth
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eir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greaterdr
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ug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their pro
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ducts before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 tg tg tg tg tg tg


OBJ: 5 t g


NAT: NCLEX Client Needs Category: Physiological Integrit tg tg tg tg tg tg


yTOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B tg


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
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severe psychological and physical dependence. Schedule I drugs have high potential for abuse
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and no recognized medical use. Schedule III drugs have some potential for abuse. Use may l
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ead to low to moderate physical dependence or high psychological dependence. Schedule IV
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drugs have low potential for abuse. Use may lead to limited physical or psychological depen
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dence.

DIF: Cognitive Level: Knowledge REF: p. 10 tg tg t g tg


OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective Cartg tg tg tg tg tg tg tg tg


e Environment
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TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an outbreak
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of smallpox?
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a. List smallpox as a health orphan disease.tg tg tg tg tg tg


b. Omit the preclinical research phase. tg tg tg tg


c. Extend the clinical research phase. tg tg tg tg


d. Fast track the investigational drug. tg tg tg tg




ANS: D tg


Once the Investigational New Drug Application has been approved, the drug can receive hig
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hest priority within the agency, which is called fast tracking. A smallpox outbreak would bec
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ome a priority concern in the world. Orphan diseases are not researched in a priority manner.
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gPreclinical research is not omitted. Extending any phase of the research would meana longer
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time to develop a vaccine. The FDA must ensure that all phases of the preclinical andclinical re
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search phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge tg tg REF: p. 7 tgtgtg tg OBJ: 5 tg