NURS 615 PHARM EXAM 1
PREP/COMPREHENSIVE GUIDE -
Maryville/ACTUAL EXAM QUESTIONS
WITH WELL DETAILED ANSWERS/GRADE
A+ ASSURED Questions and Correct
Answers/ Latest Update / Already Graded
How does hypoalbuminemia affect the process of prescribing?
Ans: Low albumin = more free drug (bc the drug can't bind to
albumin aka protein) = increased adverse effects
What is a Black Box Warning:
Ans: is considered a contraindication to administer that drug.
What is the drugs half-life?
Ans: Half-life specifically means the amount of time it takes for
an administered drug to be halfway cleared from the system.
Peak of action:
Ans: the time between drug administration and maximum
concentration of drug in the blood stream. Best therapeutic
effect.
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Duration of action:
Ans: the time between onset of action and metabolism of drug
below the minimum needed for an effect. The length of time
you have the drug in your system.
According to the WHO what is the first step in the prescribing process?
Ans: The first step is to define the patient's problem
The second step is to
Ans: specify the therapeutic objective
The third step is to
Ans: choose which drug or treatment is needed.
Step 4 of the WHO approach:
Ans: Start the treatment
Step 5 of the WHO approach:
Ans: Educate the patient
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Step 6 of the WHO approach:
Ans: Monitor the treatment
Phase 1 of drug development:
Ans: The drug is tested on healthy volunteers
Phase 2 of drug development:
Ans: trials with people who have the disease for which the drug
is thought to be effective
Phase 3 of drug development:
Ans: Large numbers of patients in medical research centers
receive the drug in phase 3. This larger sampling provides
information about infrequent or rare adverse effects. The FFA
will approve a new drug application if phase 3 studies are
satisfactory.
Phase 4 of drug development:
Ans: This phase is voluntary and involves postmarket
surveillance of the drug's therapeutic effects at the completion
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of phase 3. The pharmaceutical company receives reports from
doctors and other health care professionals about the
therapeutic results and adverse effects of the drug. Some
medications, for example, have been found to be toxic and have
been removed from the market after their initial release.
Explain first pass metabolism
Ans: much of the drug is lost in the absorption process. The
liver metabolizes many drugs, thus reduces the bioavailabilty of
the drug.
What is the fasted route of absorption:
Ans: The fastest route of absorption is inhalation, and not as
mistakenly considered the IV administration.
Why does the GI tract take longer to absorb?
Ans: The GI tract is lined with epithelial cells; drugs must
permeate through these cells in order to be absorbed into the
circulatory system.
What is One particular cellular barrier that may prevent absorption of a
given drug?
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