CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Ch. 1 — Disease Prevention & Health Promotion
Q1
Reference: Ch. 1 — Disease Prevention & Health Promotion.
accessmedicine.mhmedical.com
Question: A 58-year-old man with well-controlled hypertension
(on an ACE inhibitor) and a 30–pack-year smoking history asks
about primary prevention of cardiovascular disease. According
to current prevention principles, which preventive action is
,most appropriate to recommend first to reduce his long-term
cardiovascular risk?
A. Start low-dose aspirin daily for primary prevention.
B. Intensify tobacco-cessation interventions and arrange
smoking-cessation support.
C. Add a statin only if his LDL is >160 mg/dL.
D. Recommend daily omega-3 fatty acid supplements.
Correct answer: B
Rationale — Correct: Smoking cessation provides the greatest
immediate and long-term reduction in cardiovascular risk;
CMDT emphasizes tobacco cessation as a top prevention
priority. accessmedicine.mhmedical.com
Rationale — Incorrect:
A. Low-dose aspirin for primary prevention is now limited to
selected high-risk patients because of bleeding risk; it is not
first-line for this patient without clear high-risk indications.
accessmedicine.mhmedical.com
C. Lipid management is guided by overall atherosclerotic
cardiovascular disease (ASCVD) risk rather than a single LDL
threshold of 160 mg/dL. Statin consideration should follow risk
calculation. accessmedicine.mhmedical.com
D. Routine omega-3 supplementation is not recommended as a
primary cardiovascular prevention strategy over evidence-based
interventions like smoking cessation and statins when indicated.
accessmedicine.mhmedical.com
,Teaching Point: Smoking cessation yields the largest modifiable
reduction in CVD risk.
Citation (APA): Papadakis et al. (2025). CURRENT Medical
Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Q2
Reference: Ch. 1 — Disease Prevention & Health Promotion.
accessmedicine.mhmedical.com
Question: A 45-year-old woman with no comorbidities asks
about cancer screening. She is up to date on Pap tests. Which
screening is indicated now per population-based prevention
frameworks emphasizing age and risk?
A. Colon cancer screening beginning with colonoscopy at age 45
(or another guideline-approved method).
B. Annual chest CT screening for lung cancer.
C. PSA testing for prostate cancer.
D. Whole-body MRI screening.
Correct answer: A
Rationale — Correct: CMDT aligns with guideline
recommendations to begin colorectal cancer screening at age
45 for average-risk adults, using colonoscopy or alternative
accepted modalities. accessmedicine.mhmedical.com
, Rationale — Incorrect:
B. Annual low-dose CT lung screening is for high-risk adults
(heavy smokers meeting specific age/pack-year criteria), not all
45-year-olds. accessmedicine.mhmedical.com
C. PSA screening is not applicable to women. (PSA pertains to
men.) accessmedicine.mhmedical.com
D. Whole-body MRI is not a recommended population-based
screening test due to lack of evidence and false positives.
accessmedicine.mhmedical.com
Teaching Point: Begin average-risk colorectal screening at age
45 with guideline-approved modalities.
Citation (APA): Papadakis et al. (2025). CURRENT Medical
Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Q3
Reference: Ch. 1 — Disease Prevention & Health Promotion.
accessmedicine.mhmedical.com
Question: A 66-year-old man with well-controlled type 2
diabetes asks whether to receive the shingles (herpes zoster)
vaccine. Which statement best reflects current prevention
guidance for older adults?
A. No vaccination is indicated because prior varicella infection
confers lifelong immunity.
B. Recombinant zoster vaccine is recommended for adults ≥50
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Ch. 1 — Disease Prevention & Health Promotion
Q1
Reference: Ch. 1 — Disease Prevention & Health Promotion.
accessmedicine.mhmedical.com
Question: A 58-year-old man with well-controlled hypertension
(on an ACE inhibitor) and a 30–pack-year smoking history asks
about primary prevention of cardiovascular disease. According
to current prevention principles, which preventive action is
,most appropriate to recommend first to reduce his long-term
cardiovascular risk?
A. Start low-dose aspirin daily for primary prevention.
B. Intensify tobacco-cessation interventions and arrange
smoking-cessation support.
C. Add a statin only if his LDL is >160 mg/dL.
D. Recommend daily omega-3 fatty acid supplements.
Correct answer: B
Rationale — Correct: Smoking cessation provides the greatest
immediate and long-term reduction in cardiovascular risk;
CMDT emphasizes tobacco cessation as a top prevention
priority. accessmedicine.mhmedical.com
Rationale — Incorrect:
A. Low-dose aspirin for primary prevention is now limited to
selected high-risk patients because of bleeding risk; it is not
first-line for this patient without clear high-risk indications.
accessmedicine.mhmedical.com
C. Lipid management is guided by overall atherosclerotic
cardiovascular disease (ASCVD) risk rather than a single LDL
threshold of 160 mg/dL. Statin consideration should follow risk
calculation. accessmedicine.mhmedical.com
D. Routine omega-3 supplementation is not recommended as a
primary cardiovascular prevention strategy over evidence-based
interventions like smoking cessation and statins when indicated.
accessmedicine.mhmedical.com
,Teaching Point: Smoking cessation yields the largest modifiable
reduction in CVD risk.
Citation (APA): Papadakis et al. (2025). CURRENT Medical
Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Q2
Reference: Ch. 1 — Disease Prevention & Health Promotion.
accessmedicine.mhmedical.com
Question: A 45-year-old woman with no comorbidities asks
about cancer screening. She is up to date on Pap tests. Which
screening is indicated now per population-based prevention
frameworks emphasizing age and risk?
A. Colon cancer screening beginning with colonoscopy at age 45
(or another guideline-approved method).
B. Annual chest CT screening for lung cancer.
C. PSA testing for prostate cancer.
D. Whole-body MRI screening.
Correct answer: A
Rationale — Correct: CMDT aligns with guideline
recommendations to begin colorectal cancer screening at age
45 for average-risk adults, using colonoscopy or alternative
accepted modalities. accessmedicine.mhmedical.com
, Rationale — Incorrect:
B. Annual low-dose CT lung screening is for high-risk adults
(heavy smokers meeting specific age/pack-year criteria), not all
45-year-olds. accessmedicine.mhmedical.com
C. PSA screening is not applicable to women. (PSA pertains to
men.) accessmedicine.mhmedical.com
D. Whole-body MRI is not a recommended population-based
screening test due to lack of evidence and false positives.
accessmedicine.mhmedical.com
Teaching Point: Begin average-risk colorectal screening at age
45 with guideline-approved modalities.
Citation (APA): Papadakis et al. (2025). CURRENT Medical
Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Q3
Reference: Ch. 1 — Disease Prevention & Health Promotion.
accessmedicine.mhmedical.com
Question: A 66-year-old man with well-controlled type 2
diabetes asks whether to receive the shingles (herpes zoster)
vaccine. Which statement best reflects current prevention
guidance for older adults?
A. No vaccination is indicated because prior varicella infection
confers lifelong immunity.
B. Recombinant zoster vaccine is recommended for adults ≥50
