Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Questions (20)
1) Reference
Ch. 1 — Disease Prevention & Health Promotion — Health
Maintenance & Screening
Question (Stem)
A 58-year-old man with well-controlled type 2 diabetes and no
cardiac symptoms asks whether he should start a statin for
primary prevention. His LDL is 145 mg/dL, he has hypertension,
,and he is a current smoker. Which approach best aligns with
evidence-based preventive care?
Options
A. Defer statin therapy and focus on smoking cessation and
lifestyle modification only.
B. Initiate a moderate- to high-intensity statin because multiple
ASCVD risk factors confer net benefit.
C. Start aspirin for primary prevention and recheck lipids in 1
year.
D. Recommend ezetimibe monotherapy instead of a statin to
avoid statin adverse effects.
Correct Answer
B
Rationales
Correct (B): Patients with diabetes plus multiple atherosclerotic
cardiovascular disease (ASCVD) risk factors (e.g., elevated LDL,
hypertension, smoking) derive benefit from statin therapy for
primary prevention; statins are first-line for LDL lowering and
ASCVD risk reduction. Google Books
A: Lifestyle modification is important but insufficient alone
when clear risk factors indicate pharmacologic prevention.
C: Routine aspirin for primary prevention is not favored when
bleeding risk may outweigh benefit; aspirin is not a substitute
for statin therapy.
D: Ezetimibe may be adjunctive but is not preferred as first-line
,monotherapy instead of statin for primary prevention in high-
risk patients.
Teaching Point
Statins are first-line for primary prevention in patients with
elevated ASCVD risk.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
2) Reference
Ch. 1 — Disease Prevention & Health Promotion — Counseling
& Behavioral Interventions
Question (Stem)
A 32-year-old woman requests help to quit smoking. She has
tried brief counseling alone previously with no success. Which
initial plan most likely maximizes her chance of successful
cessation?
Options
A. Recommend brief physician advice alone and reassess in 6
months.
B. Offer combination behavioral counseling plus
pharmacotherapy (nicotine replacement or medication).
C. Suggest electronic cigarette use as the primary cessation
strategy.
, D. Advise cutting down the number of cigarettes gradually
without pharmacologic support.
Correct Answer
B
Rationales
Correct (B): Combination of counseling and pharmacotherapy
(nicotine replacement, bupropion, or varenicline) has higher
quit rates than counseling or medication alone; this is the
evidence-based first-line approach. Google Books+1
A: Brief advice alone yields modest effect; more intensive
combined approaches improve outcomes.
C: E-cigarettes are not established as first-line cessation therapy
and have uncertain long-term safety.
D: Gradual reduction without pharmacologic support has lower
success rates than structured interventions with medication.
Teaching Point
Combine counseling with pharmacotherapy to maximize
smoking cessation success.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
3) Reference
Ch. 1 — Disease Prevention & Health Promotion —
Immunizations & Adult Vaccination