CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Part 1 — Disease Prevention & Health Promotion (5 items)
Q1
Reference: Ch. 1 — Disease Prevention & Health Promotion.
Question Stem: A 58-year-old man with type 2 diabetes and a
30-pack-year smoking history asks which vaccine will most
reduce his risk of hospitalization from influenza-related
pneumococcal complications this season. Which is the best
recommendation?
Options:
A. Annual high-dose influenza vaccine plus pneumococcal
,conjugate vaccine (PCV20) per age-based schedule
B. Single lifetime dose of PPSV23 only (23-valent pneumococcal
polysaccharide)
C. Influenza vaccine only; defer pneumococcal vaccines until
age 65
D. No vaccines now; prioritize smoking cessation counseling first
Correct Answer: A
Rationales:
• Correct (A): CMDT emphasizes annual influenza
vaccination for adults with chronic disease and
recommends age- and risk-appropriate pneumococcal
vaccination (conjugate vaccine where indicated) to reduce
invasive pneumococcal disease and hospitalizations,
especially in patients with diabetes and smoking history.
Two vaccines (influenza annually + appropriate
pneumococcal vaccine) provide synergistic protection.
• Incorrect (B): PPSV23 alone is not optimal as the only
intervention for high-risk adults; conjugate vaccines (PCV)
now play an important role and influenza vaccine is still
required annually.
• Incorrect (C): Delaying pneumococcal vaccination until 65
ignores increased risk from diabetes and smoking; CMDT
supports earlier vaccination based on comorbidity.
, • Incorrect (D): Smoking cessation is essential but does not
replace immediate recommended vaccinations to reduce
short-term infectious risk.
Teaching Point: Vaccinate high-risk adults annually for influenza
and with appropriate pneumococcal vaccines per guidelines.
Citation: Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
Q2
Reference: Ch. 1 — Disease Prevention & Health Promotion.
Question Stem: A 24-year-old woman presents for a routine
visit. She is sexually active with one partner and asks about HPV
prevention. She received no prior HPV vaccine. What is the
most appropriate action?
Options:
A. Begin a two- or three-dose HPV vaccination series now based
on age and complete per schedule
B. Defer vaccination until after Pap smear results return and
only vaccinate if abnormal
C. Vaccination is unnecessary if she uses condoms consistently
D. Recommend HPV vaccination only if she plans pregnancy in
future
Correct Answer: A
Rationales:
, • Correct (A): CMDT endorses HPV vaccination for eligible
adults who have not completed the series — starting the
recommended multi-dose series at presentation maximizes
prevention of HPV-related disease.
• Incorrect (B): Pap tests screen for cervical dysplasia but do
not replace preventive HPV vaccination; waiting is
unnecessary.
• Incorrect (C): Condoms reduce but do not eliminate HPV
transmission; vaccination provides stronger primary
prevention.
• Incorrect (D): Vaccination is recommended irrespective of
pregnancy plans and should ideally be completed before
exposure but still benefits sexually active adults.
Teaching Point: Start HPV vaccination for eligible adults who
haven't completed the series at the earliest opportunity.
Citation: Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
Q3
Reference: Ch. 1 — Disease Prevention & Health Promotion.
Question Stem: A health system aims to increase colorectal
cancer screening among patients aged 50–75. Which system-
level strategy will most likely increase screening uptake?
Options:
A. Mailed fecal immunochemical test (FIT) kits with follow-up
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Part 1 — Disease Prevention & Health Promotion (5 items)
Q1
Reference: Ch. 1 — Disease Prevention & Health Promotion.
Question Stem: A 58-year-old man with type 2 diabetes and a
30-pack-year smoking history asks which vaccine will most
reduce his risk of hospitalization from influenza-related
pneumococcal complications this season. Which is the best
recommendation?
Options:
A. Annual high-dose influenza vaccine plus pneumococcal
,conjugate vaccine (PCV20) per age-based schedule
B. Single lifetime dose of PPSV23 only (23-valent pneumococcal
polysaccharide)
C. Influenza vaccine only; defer pneumococcal vaccines until
age 65
D. No vaccines now; prioritize smoking cessation counseling first
Correct Answer: A
Rationales:
• Correct (A): CMDT emphasizes annual influenza
vaccination for adults with chronic disease and
recommends age- and risk-appropriate pneumococcal
vaccination (conjugate vaccine where indicated) to reduce
invasive pneumococcal disease and hospitalizations,
especially in patients with diabetes and smoking history.
Two vaccines (influenza annually + appropriate
pneumococcal vaccine) provide synergistic protection.
• Incorrect (B): PPSV23 alone is not optimal as the only
intervention for high-risk adults; conjugate vaccines (PCV)
now play an important role and influenza vaccine is still
required annually.
• Incorrect (C): Delaying pneumococcal vaccination until 65
ignores increased risk from diabetes and smoking; CMDT
supports earlier vaccination based on comorbidity.
, • Incorrect (D): Smoking cessation is essential but does not
replace immediate recommended vaccinations to reduce
short-term infectious risk.
Teaching Point: Vaccinate high-risk adults annually for influenza
and with appropriate pneumococcal vaccines per guidelines.
Citation: Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
Q2
Reference: Ch. 1 — Disease Prevention & Health Promotion.
Question Stem: A 24-year-old woman presents for a routine
visit. She is sexually active with one partner and asks about HPV
prevention. She received no prior HPV vaccine. What is the
most appropriate action?
Options:
A. Begin a two- or three-dose HPV vaccination series now based
on age and complete per schedule
B. Defer vaccination until after Pap smear results return and
only vaccinate if abnormal
C. Vaccination is unnecessary if she uses condoms consistently
D. Recommend HPV vaccination only if she plans pregnancy in
future
Correct Answer: A
Rationales:
, • Correct (A): CMDT endorses HPV vaccination for eligible
adults who have not completed the series — starting the
recommended multi-dose series at presentation maximizes
prevention of HPV-related disease.
• Incorrect (B): Pap tests screen for cervical dysplasia but do
not replace preventive HPV vaccination; waiting is
unnecessary.
• Incorrect (C): Condoms reduce but do not eliminate HPV
transmission; vaccination provides stronger primary
prevention.
• Incorrect (D): Vaccination is recommended irrespective of
pregnancy plans and should ideally be completed before
exposure but still benefits sexually active adults.
Teaching Point: Start HPV vaccination for eligible adults who
haven't completed the series at the earliest opportunity.
Citation: Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
Q3
Reference: Ch. 1 — Disease Prevention & Health Promotion.
Question Stem: A health system aims to increase colorectal
cancer screening among patients aged 50–75. Which system-
level strategy will most likely increase screening uptake?
Options:
A. Mailed fecal immunochemical test (FIT) kits with follow-up
