Principles of Pharmacology- APEA
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The correct order of the transmission of a neurotransmitter is
presynaptic preparation followed by the:
release of a transmitter, arrival of action potential, receptor
interaction, and termination of transmitter action.
arrival of action potential, receptor interaction, release of transmitter,
and termination of transmitter action.
release of transmitter, receptor interaction, arrival of action potential,
and termination of transmitter action.
arrival of action potential, release of transmitter, receptor interaction,
and the termination of transmitter action.
Ans: arrival of action potential, release of transmitter, receptor
interaction, and the termination of transmitter action.
The term NOT associated with the pharmacokinetics of a drug is:
bioavailability.
distribution.
clearance.
pharmacodynamics.
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Ans: pharmacodynamics.
Pharmacokinetics is:
the effect the drug has on the body.
the adverse response of the drug on the body.
the effect the body has on the drug.
the clinical formulation of the drug.
Ans: the effect the body has on the drug.
Neurotransmitters are considered:
chemical substances.
electrical impulses.
vesicles.
nerve endings.
Ans: chemical substances.
When one drug displaces another drug from the binding sites on
proteins, causing an increase in the amount of "free" drug, this is
known as:
metabolism interactions.
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absorption interactions.
elimination interactions.
distribution interactions.
Ans: distribution interactions.
Which of the following actions triggers a rise in membrane or action
potential of a cell?
Opening of the voltage gated sodium ions
Closure of voltage gated sodium ions
Opening of calcium ion channel
Opening of potassium voltage gated channels
Ans: Opening of the voltage gated sodium ions
Which of the following is NOT a plasma protein that binds to
medications?
Transcobalamin
Lipoproteins
Albumin
Gamma globulins
Ans: Gamma globulins
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