D027 Advanced Pathopharmacological
Foundations
1. A 23-year-old woman comes in for prenatal counseling. While
completing her family history, she reports her brother has cystic
fibrosis. She does not know if she is a carrier. She asks if her
children will be affected by the disease.
What is an accurate way to determine the likelihood of this patient's
children being affected?
A sweat test
A genetic or a carrier
test A history and a
physical
A fertility test: A genetic or carrier test
The disease occurs when an individual inherits the mutated gene from each parent. When only one
mutated gene is inherited, the individual is labeled a carrier.
chance of the disease.
2. A 31-year-old man comes into the office for an exam. He is 6' 5
with a
high-pitched voice, and he has a moderate degree of mental
impairment. It is discovered upon exam that his body hair is sparse,
his testes are small, and he has gynecomastia.
Which genetic disorder should this patient be tested for?
Klinefelter
syndrome Turner
syndrome
Partial trisomy
Sex chromosome aneuploidy: Klinefelter syndrome: a hereditary disease also known as
47,XXY or XXY that manifests as the series of symptoms described.
3. A six-month-old female infant with failure to thrive comes in to
the office with her parents. It is noticed upon exam that the patient
has facial deformities and is jaundiced. A complete blood count
(CBC) is ordered, which reveals anemia. When that patient's blood is
,D027 Advanced Pathopharmacological
Foundations
examined under a microscope, the red blood cells appear small and
abnormally shaped. A mutational analysis is ordered, and alpha
thalassemia is diagnosed.
What is the likelihood of incidence of these parent's future children
having alpha thalassemia?
,D027 Advanced Pathopharmacological
Foundations
25%
100%
0%
50%: 25% or 1/4 chance
4. A 64-year-old male truck driver comes in complaining of pain in his
lower left calf. He states he drives eight to ten hours per day.
Upon exam, swelling and mottled coloring are noted in the
patient's calf. A D-dimer test is ordered and comes back positive.
Which additional test should be ordered to confirm a diagnosis in this
patient?
A CT scan
A Doppler Ultrasound
The D-dimer test again
A clotting factors test: A Doppler Ultrasound is the initial test of choice for patients who are not
initially stratified according to clinical pretest probability (PTP) as being low, moderate, or high risk for DV
5. A 54-year-old man comes into a clinic for a routine visit. His initial BP
is 148/92. After a recheck 15 minutes later, his BP is 140/90. He
states he suffers from "white coat hypertension." He states he has no
history of high blood pressure and no family history of high blood
pressure.
Which nursing intervention would assist this patient in receiving a
clinical diagnosis of hypertension?
Ordering the patient a cholesterol level test
Checking the patient's blood pressure in three
months Completing a biochemical blood profile
Completing an ambulatory blood pressure assessment: Completing an
ambulatory BP assessment.
Assessing blood pressure in a location of comfort like the home environment when no professional is
present will enable the ability to determine his blood pressure under routine circumstances.
6. A 58-year-old woman comes in complaining of retrosternal chest
,D027 Advanced Pathopharmacological
Foundations
pain, wors- ening with recumbent position. She states she has had
a low-grade fever for
Foundations
1. A 23-year-old woman comes in for prenatal counseling. While
completing her family history, she reports her brother has cystic
fibrosis. She does not know if she is a carrier. She asks if her
children will be affected by the disease.
What is an accurate way to determine the likelihood of this patient's
children being affected?
A sweat test
A genetic or a carrier
test A history and a
physical
A fertility test: A genetic or carrier test
The disease occurs when an individual inherits the mutated gene from each parent. When only one
mutated gene is inherited, the individual is labeled a carrier.
chance of the disease.
2. A 31-year-old man comes into the office for an exam. He is 6' 5
with a
high-pitched voice, and he has a moderate degree of mental
impairment. It is discovered upon exam that his body hair is sparse,
his testes are small, and he has gynecomastia.
Which genetic disorder should this patient be tested for?
Klinefelter
syndrome Turner
syndrome
Partial trisomy
Sex chromosome aneuploidy: Klinefelter syndrome: a hereditary disease also known as
47,XXY or XXY that manifests as the series of symptoms described.
3. A six-month-old female infant with failure to thrive comes in to
the office with her parents. It is noticed upon exam that the patient
has facial deformities and is jaundiced. A complete blood count
(CBC) is ordered, which reveals anemia. When that patient's blood is
,D027 Advanced Pathopharmacological
Foundations
examined under a microscope, the red blood cells appear small and
abnormally shaped. A mutational analysis is ordered, and alpha
thalassemia is diagnosed.
What is the likelihood of incidence of these parent's future children
having alpha thalassemia?
,D027 Advanced Pathopharmacological
Foundations
25%
100%
0%
50%: 25% or 1/4 chance
4. A 64-year-old male truck driver comes in complaining of pain in his
lower left calf. He states he drives eight to ten hours per day.
Upon exam, swelling and mottled coloring are noted in the
patient's calf. A D-dimer test is ordered and comes back positive.
Which additional test should be ordered to confirm a diagnosis in this
patient?
A CT scan
A Doppler Ultrasound
The D-dimer test again
A clotting factors test: A Doppler Ultrasound is the initial test of choice for patients who are not
initially stratified according to clinical pretest probability (PTP) as being low, moderate, or high risk for DV
5. A 54-year-old man comes into a clinic for a routine visit. His initial BP
is 148/92. After a recheck 15 minutes later, his BP is 140/90. He
states he suffers from "white coat hypertension." He states he has no
history of high blood pressure and no family history of high blood
pressure.
Which nursing intervention would assist this patient in receiving a
clinical diagnosis of hypertension?
Ordering the patient a cholesterol level test
Checking the patient's blood pressure in three
months Completing a biochemical blood profile
Completing an ambulatory blood pressure assessment: Completing an
ambulatory BP assessment.
Assessing blood pressure in a location of comfort like the home environment when no professional is
present will enable the ability to determine his blood pressure under routine circumstances.
6. A 58-year-old woman comes in complaining of retrosternal chest
,D027 Advanced Pathopharmacological
Foundations
pain, wors- ening with recumbent position. She states she has had
a low-grade fever for
