AP BIO 2 2025-2026 RELEASED TEST
(MACKIES)
1. A dog is following the scent of a jack rabbit. Which if the following accurately
describes how the dog's brain integrates information for smell?
(A) Chemoreceptors in the brain send impulses for smell in the nasal cavity.
(B) Chemoreceptor cells in the nasal cavity send impulses to the appropriate area of the
brain.
(C) Chemoreceptors on epithelial cells of the tongue send hormones to the appropriate
area of the brain.
(D) Receptors originating in the nose send action potentials to the motor regions of the
brain. - Correct Answers -B
2. Thrips are insects that feed on rose pollen. Scientists noted that the thrips population
increased in the spring and decreased dramatically during the summer. The
researchers hypothesized that food abundance was the limiting factor for the
population. Which of the following types of data would be the most useful for the
scientists to collect at regular intervals on a designated test plot of rose plants?
(A) Amount of sunlight
(B) Mean temperature (C)
(C) Density of rose pollen produced (g/m2)
(D) Amount of pollen produced by each flower (g/flower) - Correct Answers -C
3. If ATP breakdown (hydrolysis) is inhibited, which if the following types of movement
across cell membranes is also inhibited?
(A) Movement of oxygen into a cell
(B) Movement of water through aquaporins
(C) Passage of a solute against its concentration gradient
(D) Facilitated diffusion of a permeable substance - Correct Answers -C
4. Undersea landslide can disrupt marine habitats by burying organisms that live on the
ocean floor. The graph above shows the size of a population of a certain organism that
lives on the ocean floor. The population was affected by a recent landslide at the time
indicated on the graph. Which of the following best predicts how the population will be
affected by the landslide?
(A) The surviving organisms will evolve into a new species
(B) The reduced population will likely have allelic frequencies that are different from the
initial population
(C) The population will adapt to deeper waters to avoid future landslides
, (D) The reduced population will have a greater number of different genes than the initial
population - Correct Answers -B
5. Which of the following questions is most relevant to understanding the Calvin cycle?
(A) How does chlorophyll capture light?
(B) How is ATP used in the formation of 3-carbon carbohydrates?
(C) How is NAD+ reduced to NADPH?
(D) How is ATP produced in chemiosmosis? - Correct Answers -B
6. Rosalind Franklin's x-ray diffraction images taken in the 1950s most directly support
which of he following claims about DNA?
(A) The ratios of base pairs are constant
(B) The nucleotide sequence determines genetic information
(C) The two strands of DNA are antiparallel
(D) The basic molecular structure is a helix - Correct Answers -D
7. The equation above shows one of the reversible reactions that occur in the blood.
After exercise, an athlete's blood pH has dropped below the normal level. How will
normal blood pH be restored?
(A) An increase in 02 concentration in the plasma will lead to an increase in H+
concentration
(B) An increase in temperature will lead to an increase in H+ concentration
(C) An increase in sweating will lead to a decrease in OH- and H+ concentration
(D) An increase in breathing rate will lead to a decrease in blood CO2 and H+
concentration - Correct Answers -D
8. A researcher is investigating the relationship between the existing species diversity in
a community and the ability of an introduced nonnative species to destabilize the
community. Which of the following graphs is most consistent with the claim that
communities with high diversity are more resistant to change than are communities with
low diversity?
(A)
(B)
(C)
(D) - Correct Answers –D
46. The figure above shows a model of a ligand precursor being cleaved to produce an
active ligand that binds to a specific receptor. Which of the following is most likely to
reduce the binding of the active ligand to its receptor?
(A) A change in the cytoskeleton attachment of transmembrane protein
(B) The presence of a large amount of the precursor form of the ligand
(C) An increase in the ratio of the number of unsaturated to the number of saturated
fatty acid tails of the membrane lipids
(D) A mutation in the receptor gene that causes a substitution of a charged amino acid
for a nonpolar amino acid in the ligand binding site of the receptor - Correct Answers -D
(MACKIES)
1. A dog is following the scent of a jack rabbit. Which if the following accurately
describes how the dog's brain integrates information for smell?
(A) Chemoreceptors in the brain send impulses for smell in the nasal cavity.
(B) Chemoreceptor cells in the nasal cavity send impulses to the appropriate area of the
brain.
(C) Chemoreceptors on epithelial cells of the tongue send hormones to the appropriate
area of the brain.
(D) Receptors originating in the nose send action potentials to the motor regions of the
brain. - Correct Answers -B
2. Thrips are insects that feed on rose pollen. Scientists noted that the thrips population
increased in the spring and decreased dramatically during the summer. The
researchers hypothesized that food abundance was the limiting factor for the
population. Which of the following types of data would be the most useful for the
scientists to collect at regular intervals on a designated test plot of rose plants?
(A) Amount of sunlight
(B) Mean temperature (C)
(C) Density of rose pollen produced (g/m2)
(D) Amount of pollen produced by each flower (g/flower) - Correct Answers -C
3. If ATP breakdown (hydrolysis) is inhibited, which if the following types of movement
across cell membranes is also inhibited?
(A) Movement of oxygen into a cell
(B) Movement of water through aquaporins
(C) Passage of a solute against its concentration gradient
(D) Facilitated diffusion of a permeable substance - Correct Answers -C
4. Undersea landslide can disrupt marine habitats by burying organisms that live on the
ocean floor. The graph above shows the size of a population of a certain organism that
lives on the ocean floor. The population was affected by a recent landslide at the time
indicated on the graph. Which of the following best predicts how the population will be
affected by the landslide?
(A) The surviving organisms will evolve into a new species
(B) The reduced population will likely have allelic frequencies that are different from the
initial population
(C) The population will adapt to deeper waters to avoid future landslides
, (D) The reduced population will have a greater number of different genes than the initial
population - Correct Answers -B
5. Which of the following questions is most relevant to understanding the Calvin cycle?
(A) How does chlorophyll capture light?
(B) How is ATP used in the formation of 3-carbon carbohydrates?
(C) How is NAD+ reduced to NADPH?
(D) How is ATP produced in chemiosmosis? - Correct Answers -B
6. Rosalind Franklin's x-ray diffraction images taken in the 1950s most directly support
which of he following claims about DNA?
(A) The ratios of base pairs are constant
(B) The nucleotide sequence determines genetic information
(C) The two strands of DNA are antiparallel
(D) The basic molecular structure is a helix - Correct Answers -D
7. The equation above shows one of the reversible reactions that occur in the blood.
After exercise, an athlete's blood pH has dropped below the normal level. How will
normal blood pH be restored?
(A) An increase in 02 concentration in the plasma will lead to an increase in H+
concentration
(B) An increase in temperature will lead to an increase in H+ concentration
(C) An increase in sweating will lead to a decrease in OH- and H+ concentration
(D) An increase in breathing rate will lead to a decrease in blood CO2 and H+
concentration - Correct Answers -D
8. A researcher is investigating the relationship between the existing species diversity in
a community and the ability of an introduced nonnative species to destabilize the
community. Which of the following graphs is most consistent with the claim that
communities with high diversity are more resistant to change than are communities with
low diversity?
(A)
(B)
(C)
(D) - Correct Answers –D
46. The figure above shows a model of a ligand precursor being cleaved to produce an
active ligand that binds to a specific receptor. Which of the following is most likely to
reduce the binding of the active ligand to its receptor?
(A) A change in the cytoskeleton attachment of transmembrane protein
(B) The presence of a large amount of the precursor form of the ligand
(C) An increase in the ratio of the number of unsaturated to the number of saturated
fatty acid tails of the membrane lipids
(D) A mutation in the receptor gene that causes a substitution of a charged amino acid
for a nonpolar amino acid in the ligand binding site of the receptor - Correct Answers -D