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, Tumor secretes PTH-related protein --> hypercalcemia. Usually involves
multiple myeloma, SCC, and breast cancers
Ca >10.5
S/S=mental status changes, weakness, constipation, coma
TLS labs
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increased calcium, potassium, and uric acid
need to maintain hydration, monitor UOP, and limit K and phos products
during high risk period (seven days after tx) for prevention
Etiologies of iron deficiency anemia (IDA)
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Issue is with RBC PRODUCTION
1. Continual blood loss (menorrhagia, ulcers, ulcerative colitis, GI bleeds)
2. Increased need during pregnancy
3. Insufficient dietary intake (most common in 6 months to 2 years of age)
4.malignancy
5.IBD or malabsorption
most common in children and pregnant women!
, prevention of iron deficiency anemia in children
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- Start iron supplementation at age 4 mons
- When starting baby food, they need iron fortified foods
*Premature & low birth weight infants' in utero iron stores are depleted
sooner (in 1-2 mons) so start supplementation sooner
reticulocyte count
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measurement of the number of circulating reticulocytes, immature
erythrocytes in a blood specimen. tells whether the anemia is caused by
decreased production of RBC's or increased loss of RBC's.
normal=0.5-2%
normal response to decreased RBC's is increased reticulocytes
Lead poisoning
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Can cause a microcytic anemia, increases RBC destruction
-Asymptomatic, GI, neurological, behavioral symptoms
-Lead level >5