Clayton’s Basic Pharmacology For Nurses
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20th Edition B
By Michelle J. Willihnganz & Samuel L.
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Gurevitz B
Chapter Guide 1-48|Latest
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pg. 1
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, Chapter 01: Drug Definitions, Standards, and Information SourcesB B B B B B B
MULTIPLE CHOICE
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1. Which name identifies a drug listed by the US Food and Drug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
CORRECT ANSWER: C B B
The official name is the name under which a drug is listed by the FDA. The brand name, or trademark, is the
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name given to a drug by its manufacturer. The nonproprietary, or generic, name is provided by the United
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States Adopted Names Council.
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DIF: Cognitive Level: Knowledge B B REF: p. 9 B B
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care Environment TOP: Nursing Process
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Step: Assessment
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2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database
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c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts B B
CORRECT ANSWER: C
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United States Pharmacopoeia/National Formulary contains information specific to nutritional supplements.
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USP Dictionary of USAN & International Drug Names is a compilation of drug names, pronunciation guide,
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and possible future FDA approved drugs; it does not include nutritional supplements. Natural Medicines
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Comprehensive Database contains evidence-based information on herbal medicines and herbal combination
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products; it does not include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge B B REF: p. 4 B B OBJ: 3 NAT: NCLEX Client Needs Category:
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Physiological Integrity
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pg. 2 B
,TOP: Nursing Process Step: AssessmentCON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons
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b. Drug Interaction Facts B B
c. Handbook on Injectable Drugs B B B
d. Martindale—The Complete Drug Reference B B B
CORRECT ANSWER: A
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Drug Facts and Comparisons contains drug monographs that describe all drugs in a therapeutic class.
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Monographs are formatted as tables to allow comparison of similar products, brand names, manufacturers,
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cost indices, and available dosage forms Online version is available.
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DIF: Cognitive Level: Knowledge B B REF: p. 4 Table 1.2
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OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: AssessmentCON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-entity drug available in the
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United States and describes therapeutic uses of drugs, including approved and unapproved uses?
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a. Martindale: The Complete Drug Reference B B B B
b. AHFS Drug Information B B
c. Drug Reference B
d. Drug Facts and Comparisons
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CORRECT ANSWER: B
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AHFS Drug Information contains monographs about virtually every single-entity drug available in the
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United States and describes therapeutic uses of drugs, including approved and unapproved uses.
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DIF: Cognitive Level: Knowledge B B REF: p. 4 Table 1.2
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OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
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pg. 3
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, 5. Which online drug reference makes available to healthcare providers and the public a standard,
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comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index B B
b. American Hospital Formulary B B
c. DailyMed
d. Drug Reference B
CORRECT ANSWER: C
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DailyMed makes available to healthcare providers and the public a standard, comprehensive, up-to-date look
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up and downloadable resource about medicines. The American Drug Index is not appropriate for patient use.
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The American Hospital Formulary is not appropriate for patient use. The drug reference is not appropriate for
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patient use.
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DIF: Cognitive Level: Knowledge B B REF: p. 3 | p. 4 OBJ: 3 NAT: NCLEX Client Needs Category:
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Physiological Integrity
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TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938)
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b. Durham Humphrey Amendment (1952) B B B
c. Controlled Substances Act (1970) B B B
d. Kefauver Harris Drug Amendment (1962) B B B B
CORRECT ANSWER: A
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The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of all drugs
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before marketing. Later amendments and acts helped tighten FDA control and ensure drug safety. The
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Durham Humphrey Amendment defines the kinds of drugs that cannot be used safely without medical
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supervision and restricts their sale to prescription by a licensed practitioner. The Controlled Substances Act
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addresses only controlled substances and their categorization. The Kefauver Harris Drug Amendment
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ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to the FDA the
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effectiveness of their products before marketing them.
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DIF: Cognitive Level: Knowledge B B REF: p. 5 Table l.3 B B B B
pg. 4 B