Surgery COMAT Exam (2025-2026) – Latest Questions
and Verified Answers
Introduction:
This document contains the most recent and verified question set for
the 2025 Surgery COMAT (Comprehensive Osteopathic Medical
Achievement Test) exam. It includes detailed questions and accurate
answers covering all high-yield surgical topics such as trauma,
gastrointestinal surgery, vascular, endocrine, and perioperative
management. Designed for medical students preparing for the
COMAT or Step 2 rotations, this material provides concise, exam-
focused content that mirrors current testing standards.
Exam Questions and Answers
What is surgical indication for full thickness large bowel injuries in
the setting of minimal fecal contamination? --- correct precise
answer ---simple repair
Gold standard initial treatment for GERD --- correct precise answer
---PPI = most potent inhibitors of gastric secretion
Metoclopramide --- correct precise answer ---is a prokinetic and
antiemetic that is only recommended in patients with GERD
symptoms due to esophageal, extraesophageal and/or gastric
dysmotility
,What is the agent of choice for treating GERD in pregnancy? ---
correct precise answer ---Sucralfate: adheres to the mucosal
surface, promotes healing and protects from peptic injury
What is a nondestructive colonic injury defined as? --- correct
precise answer ---Wounds that involve less than 50% of the bowel
wall without devascularization
Preferred method of diagnosing PUD? --- correct precise answer ---
Upper GI endoscopy
Signs of benign gastric/duodenal ulcer? --- correct precise answer -
--ulcer base is commonly smooth and flat often covered by gray,
fibrous exudate, slightly raised margin
Tissue is erythematous and friable
Dieulafoy's lesions? --- correct precise answer ---Single, large,
tortuous arteriole in the submucosa which does not undergo normal
branching or a branch with caliber of 1-5 mm (more than 10 times
the normal diameter of mucosal capillaries)
lesions bleed into the GI tract through minute defects in the mucosa
,most occur in upper part of stomach within 6 cm of GE junction on
the lesser curvature
2 categories of Acute Gastritis? --- correct precise answer ---
Erosive (eg, superficial erosions, deep erosions, hemorrhagic
erosions) and nonerosive (generally caused by H. pylori)
Symptoms of acute gastritis? --- correct precise answer ---gnawing
or burning epigastric distress, occasionally accompanied by nausea
and/or vomiting
pain may improve or worsen with eating
Antibiotic protocol for ruptured appendicitis? --- correct precise
answer ---in ruptured appendicitis patients should receive pre-
operative antibiotc as well as post-operative antibiotics until the
patient is afebrile and has a normal WBC coun, typically 3-5 days
Antibiotic protocol for non-ruptured appendicitis? --- correct
precise answer ---Pre-operative antibiotics are given to all patients
with appendicitis. If there is no rupture of the appendix then post-
operative antibiotics may be indicated for less than 24 hours
Intussussception in adults is _________ until proven otherwise? ---
correct precise answer ---a mass
, What is one of the most common complications of PJS patients? ---
correct precise answer ---intussussception
Diastasis recti? and who gets it? --- correct precise answer ---
separation of the abdominal wall along the linea alba is stretched
presents in infancy or multiparous women
Treatment of diastasis recti? --- correct precise answer ---PT,
abdominal muscle exercises, for those that fail to progress surgery
is warranted (plication of the linea alba)
Spigelian hernia --- correct precise answer ---Defect in the spigel's
fascia between the rectus abdominis and external oblique muscle
no bulge on physical exam, presents with pain, operative treatment
within mesh depending on defect size
diagnose with CT
Pediatric GERD clinical presentation? --- correct precise answer ---
irritable and crying, sleep disturbance, decreased appetite,
and Verified Answers
Introduction:
This document contains the most recent and verified question set for
the 2025 Surgery COMAT (Comprehensive Osteopathic Medical
Achievement Test) exam. It includes detailed questions and accurate
answers covering all high-yield surgical topics such as trauma,
gastrointestinal surgery, vascular, endocrine, and perioperative
management. Designed for medical students preparing for the
COMAT or Step 2 rotations, this material provides concise, exam-
focused content that mirrors current testing standards.
Exam Questions and Answers
What is surgical indication for full thickness large bowel injuries in
the setting of minimal fecal contamination? --- correct precise
answer ---simple repair
Gold standard initial treatment for GERD --- correct precise answer
---PPI = most potent inhibitors of gastric secretion
Metoclopramide --- correct precise answer ---is a prokinetic and
antiemetic that is only recommended in patients with GERD
symptoms due to esophageal, extraesophageal and/or gastric
dysmotility
,What is the agent of choice for treating GERD in pregnancy? ---
correct precise answer ---Sucralfate: adheres to the mucosal
surface, promotes healing and protects from peptic injury
What is a nondestructive colonic injury defined as? --- correct
precise answer ---Wounds that involve less than 50% of the bowel
wall without devascularization
Preferred method of diagnosing PUD? --- correct precise answer ---
Upper GI endoscopy
Signs of benign gastric/duodenal ulcer? --- correct precise answer -
--ulcer base is commonly smooth and flat often covered by gray,
fibrous exudate, slightly raised margin
Tissue is erythematous and friable
Dieulafoy's lesions? --- correct precise answer ---Single, large,
tortuous arteriole in the submucosa which does not undergo normal
branching or a branch with caliber of 1-5 mm (more than 10 times
the normal diameter of mucosal capillaries)
lesions bleed into the GI tract through minute defects in the mucosa
,most occur in upper part of stomach within 6 cm of GE junction on
the lesser curvature
2 categories of Acute Gastritis? --- correct precise answer ---
Erosive (eg, superficial erosions, deep erosions, hemorrhagic
erosions) and nonerosive (generally caused by H. pylori)
Symptoms of acute gastritis? --- correct precise answer ---gnawing
or burning epigastric distress, occasionally accompanied by nausea
and/or vomiting
pain may improve or worsen with eating
Antibiotic protocol for ruptured appendicitis? --- correct precise
answer ---in ruptured appendicitis patients should receive pre-
operative antibiotc as well as post-operative antibiotics until the
patient is afebrile and has a normal WBC coun, typically 3-5 days
Antibiotic protocol for non-ruptured appendicitis? --- correct
precise answer ---Pre-operative antibiotics are given to all patients
with appendicitis. If there is no rupture of the appendix then post-
operative antibiotics may be indicated for less than 24 hours
Intussussception in adults is _________ until proven otherwise? ---
correct precise answer ---a mass
, What is one of the most common complications of PJS patients? ---
correct precise answer ---intussussception
Diastasis recti? and who gets it? --- correct precise answer ---
separation of the abdominal wall along the linea alba is stretched
presents in infancy or multiparous women
Treatment of diastasis recti? --- correct precise answer ---PT,
abdominal muscle exercises, for those that fail to progress surgery
is warranted (plication of the linea alba)
Spigelian hernia --- correct precise answer ---Defect in the spigel's
fascia between the rectus abdominis and external oblique muscle
no bulge on physical exam, presents with pain, operative treatment
within mesh depending on defect size
diagnose with CT
Pediatric GERD clinical presentation? --- correct precise answer ---
irritable and crying, sleep disturbance, decreased appetite,
