Blood Bank Rotation Final Exam
Questions with 100% Correct Answers
Which immunodominant sugar and antigen is associated with gene H? Correct
Answer: -L-fucose
-H antigen
Which immunodominant sugar and antigen is associated with gene A? Correct
Answer: -acetylgalactosamine
-A antigen
Which immunodominant sugar and antigen is associated with gene B? Correct
Answer: -galactose
-B antigen
Which immunodominant sugar and antigen is associated with gene O? Correct
Answer: none
What gene(s) are associated with group O? Correct Answer: H
What gene(s) are associated with group A? Correct Answer: H, A
What gene(s) are associated with group B? Correct Answer: H, B
What class are ABO antibodies? Correct Answer: IgM
When can immune (IgG) anti-A and anti-B be formed? Correct Answer: -
mothers with ABO incompatible babies
-following ABO incompatible transfusions
,-without any apparent cause
What percentage of all group A individuals are A1? Correct Answer: 80%
What percentage of all group A individuals are A2? Correct Answer: 19%
What percentage of A2 individuals develop anti-A1? Correct Answer: 1-8%
What percentage of A2B individuals develop anti-A1? Correct Answer: 22-35%
Which A group has the most H antigen sites? Correct Answer: A2
What is true about the ABO serology of newborns? Correct Answer: ABO
antibody production is initiated at birth but present in low titers
What antibodies are present in the A1 phenotype? Correct Answer: -anti-A
-anti-A,B
-anti-A1 lectin
Which antibodies are present in the A2 phenotype? Correct Answer: -anti-A
-anti-A,B
Which antibodies are present in the A3 phenotype? Correct Answer: -mixed
field anti-A
-neg or W+ anti-A,B
-sometimes anti-A1 lectin
Which antibodies are present in the A4 phenotype? Correct Answer: -neg or W+
anti-A
,-mixed field anti-A,B
-sometimes anti-A1 lectin
Which blood group reacts least strongly with an anti-H produced in an A1B
individual? Correct Answer: group A1
Plasma from a group O individual contains what naturally occurring antibodies?
Correct Answer: -anti-A
-anti-B
-anti-AB
Why is anti-A,B sometimes used to group patients? Correct Answer: -if the
patient has a subgroup, especially A3
-used to determine the presence of erythrocytic antigens A and/or B on the
surface of RBCs
What is the frequency of the O phenotype in white and black populations?
Correct Answer: -white: 45%
-black: 49%
What is the frequency of the A phenotype in white and black populations?
Correct Answer: -white: 43%
-black: 27%
What is the frequency of the A1 phenotype in white and black populations?
Correct Answer: -white: 33%
-black: 19%
, What is the frequency of the A2 phenotype in white and black populations?
Correct Answer: -white: 7%
-black: 5%
What is the frequency of the B phenotype in white and black populations?
Correct Answer: -white: 11%
-black: 20%
What is the frequency of the AB phenotype in white and black populations?
Correct Answer: -white: 4%
-black: 4%
List the six phenotypes inherited by the allelic genes A1, A2, B, and O. Correct
Answer: O, A1, A2, B, A1B, A2B
List the ten genotypes responsible for the phenotypes inherited by the allelic
genes A1, A2, B, and O Correct Answer: AA
AO
BB
BO
A1A2
A2O
A1B
A2B
Questions with 100% Correct Answers
Which immunodominant sugar and antigen is associated with gene H? Correct
Answer: -L-fucose
-H antigen
Which immunodominant sugar and antigen is associated with gene A? Correct
Answer: -acetylgalactosamine
-A antigen
Which immunodominant sugar and antigen is associated with gene B? Correct
Answer: -galactose
-B antigen
Which immunodominant sugar and antigen is associated with gene O? Correct
Answer: none
What gene(s) are associated with group O? Correct Answer: H
What gene(s) are associated with group A? Correct Answer: H, A
What gene(s) are associated with group B? Correct Answer: H, B
What class are ABO antibodies? Correct Answer: IgM
When can immune (IgG) anti-A and anti-B be formed? Correct Answer: -
mothers with ABO incompatible babies
-following ABO incompatible transfusions
,-without any apparent cause
What percentage of all group A individuals are A1? Correct Answer: 80%
What percentage of all group A individuals are A2? Correct Answer: 19%
What percentage of A2 individuals develop anti-A1? Correct Answer: 1-8%
What percentage of A2B individuals develop anti-A1? Correct Answer: 22-35%
Which A group has the most H antigen sites? Correct Answer: A2
What is true about the ABO serology of newborns? Correct Answer: ABO
antibody production is initiated at birth but present in low titers
What antibodies are present in the A1 phenotype? Correct Answer: -anti-A
-anti-A,B
-anti-A1 lectin
Which antibodies are present in the A2 phenotype? Correct Answer: -anti-A
-anti-A,B
Which antibodies are present in the A3 phenotype? Correct Answer: -mixed
field anti-A
-neg or W+ anti-A,B
-sometimes anti-A1 lectin
Which antibodies are present in the A4 phenotype? Correct Answer: -neg or W+
anti-A
,-mixed field anti-A,B
-sometimes anti-A1 lectin
Which blood group reacts least strongly with an anti-H produced in an A1B
individual? Correct Answer: group A1
Plasma from a group O individual contains what naturally occurring antibodies?
Correct Answer: -anti-A
-anti-B
-anti-AB
Why is anti-A,B sometimes used to group patients? Correct Answer: -if the
patient has a subgroup, especially A3
-used to determine the presence of erythrocytic antigens A and/or B on the
surface of RBCs
What is the frequency of the O phenotype in white and black populations?
Correct Answer: -white: 45%
-black: 49%
What is the frequency of the A phenotype in white and black populations?
Correct Answer: -white: 43%
-black: 27%
What is the frequency of the A1 phenotype in white and black populations?
Correct Answer: -white: 33%
-black: 19%
, What is the frequency of the A2 phenotype in white and black populations?
Correct Answer: -white: 7%
-black: 5%
What is the frequency of the B phenotype in white and black populations?
Correct Answer: -white: 11%
-black: 20%
What is the frequency of the AB phenotype in white and black populations?
Correct Answer: -white: 4%
-black: 4%
List the six phenotypes inherited by the allelic genes A1, A2, B, and O. Correct
Answer: O, A1, A2, B, A1B, A2B
List the ten genotypes responsible for the phenotypes inherited by the allelic
genes A1, A2, B, and O Correct Answer: AA
AO
BB
BO
A1A2
A2O
A1B
A2B
