ADVANCED PATHOPHYSIOLOGY UTMB 5355
ACTUAL EXAMINATION TEST 2026 QUESTIONS
WITH SOLUTIONS GRADED A+
◉ Which of the following is a role of histamine when released by mast
cells. Answer: Increased Vascular Permeability
◉ Which of the following results when histamine attaches to the H1
receptor. Answer: Smooth muscle contraction, increased chemotaxis,
stimulation of prostaglandin synthesis
◉ Which chemical mediator is responsible for prolonged asthma
symptoms such as bronchoconstriction and inflammation. Answer:
Leukotrienes
◉ Which of the following are an active modulator of allergic reactions
in the immune system. Answer: Eosinophils
◉ directs movement of cells along a chemical gradient attracting
eosinophils and neutrophils to the site of inflammation.. Answer:
Chemotaxis
,◉ What are the functions of interferons. Answer: Protect against viral
infection, modulate inflammatory response
◉ Your patient has seasonal allergic rhinitis. Which type of
hypersensitivity reaction is this. Answer: Type 1
◉ Your patient has diagnosis of Grave's disease. Which type of
Hypersensitivity reaction is this. Answer: Type 2
◉ Which of the following is a type III hypersensitivity reaction. Answer:
Glomerulonephritis
◉ Which of the following statement is true regarding Type IV
Reactions. Answer: The reaction is mediated by T lymphocytes
◉ Which of the following statements are true regarding exotoxins.
Answer: damage cell membranes, activate second messengers, inhibit
protein synthesis
◉ immunity is produced by an individual after natural exposure to an
antigen or after immunization. Answer: Active
◉ immunity produces immunoglobulins that bind to antigens and
neutralize their effects. Answer: Humoral
, ◉ stimulates the proliferation of T cells and B cells during
inflammation. Answer: Interleukins
◉ Catecholamines decrease which of the following immune system cells
during chronic stress. Answer: Natural Killer cells
◉ interfere with insulin signaling leading to insulin resistance in stress,
obesity, and Type 2 Diabetes.. Answer: Pro-inflammatory cytokines
◉ what type of immunity is produced when an immunoglobulin crosses
the placenta. Answer: Passive acquired
◉ the normal microbiome. Answer: The body's surfaces are colonized
with a variety of microorganisms, Surfaces, such as skin and mucous
membranes of eyes, upper and lower GI tracts, urethra and vagina are
colonized by a combination of bacteria and fungi that are unique to a
particular location and individual.
◉ If immunocompromised the microbiome can lead to. Answer:
opportunistic infections or loss of integrity of the body surface areas.
◉ Type 1 hypersensitivity example. Answer: seasonal rhinitis
ACTUAL EXAMINATION TEST 2026 QUESTIONS
WITH SOLUTIONS GRADED A+
◉ Which of the following is a role of histamine when released by mast
cells. Answer: Increased Vascular Permeability
◉ Which of the following results when histamine attaches to the H1
receptor. Answer: Smooth muscle contraction, increased chemotaxis,
stimulation of prostaglandin synthesis
◉ Which chemical mediator is responsible for prolonged asthma
symptoms such as bronchoconstriction and inflammation. Answer:
Leukotrienes
◉ Which of the following are an active modulator of allergic reactions
in the immune system. Answer: Eosinophils
◉ directs movement of cells along a chemical gradient attracting
eosinophils and neutrophils to the site of inflammation.. Answer:
Chemotaxis
,◉ What are the functions of interferons. Answer: Protect against viral
infection, modulate inflammatory response
◉ Your patient has seasonal allergic rhinitis. Which type of
hypersensitivity reaction is this. Answer: Type 1
◉ Your patient has diagnosis of Grave's disease. Which type of
Hypersensitivity reaction is this. Answer: Type 2
◉ Which of the following is a type III hypersensitivity reaction. Answer:
Glomerulonephritis
◉ Which of the following statement is true regarding Type IV
Reactions. Answer: The reaction is mediated by T lymphocytes
◉ Which of the following statements are true regarding exotoxins.
Answer: damage cell membranes, activate second messengers, inhibit
protein synthesis
◉ immunity is produced by an individual after natural exposure to an
antigen or after immunization. Answer: Active
◉ immunity produces immunoglobulins that bind to antigens and
neutralize their effects. Answer: Humoral
, ◉ stimulates the proliferation of T cells and B cells during
inflammation. Answer: Interleukins
◉ Catecholamines decrease which of the following immune system cells
during chronic stress. Answer: Natural Killer cells
◉ interfere with insulin signaling leading to insulin resistance in stress,
obesity, and Type 2 Diabetes.. Answer: Pro-inflammatory cytokines
◉ what type of immunity is produced when an immunoglobulin crosses
the placenta. Answer: Passive acquired
◉ the normal microbiome. Answer: The body's surfaces are colonized
with a variety of microorganisms, Surfaces, such as skin and mucous
membranes of eyes, upper and lower GI tracts, urethra and vagina are
colonized by a combination of bacteria and fungi that are unique to a
particular location and individual.
◉ If immunocompromised the microbiome can lead to. Answer:
opportunistic infections or loss of integrity of the body surface areas.
◉ Type 1 hypersensitivity example. Answer: seasonal rhinitis
