Answers Verified 100% Correct
What is the most frequently employed automated method for glucose? - ANSWER
Coupled enzyme system consisting of glucose oxidase and peroxidase.
Contamination of the glucose reagent with catalase is a problem with which glucose
method? - ANSWER Glucose oxidase
What is the hexokinase methodology for glucose determination based on? - ANSWER
Reduced coenzyme read at 340 nm
What is the normal fasting blood glucose (FBS) reference range for adults? - ANSWER
70-110 mg/dL
Prenatal patients with borderline blood glucose levels are further evaluated by which
test? - ANSWER 3-hour glucose tolerance test (GTT)
Which test gives a 2-3 month picture of a diabetic's glucose levels? - ANSWER
Hemoglobin A1C
What does the presence of urinary ketones MOST likely indicate? - ANSWER Storage
lipids are being used as the primary energy source.
Which one of the following tests is used to differentiate between inappropriate
exogenous insulin administration and endogenous insulin production? - ANSWER
Cpeptide
The "port wine" color of some urines can be attributed to which of the following? -
ANSWER Porphyrins
p-dimethylaminobenzaldehyde is a constituent of which reagent? - ANSWER Ehrlich
Both porphobilinogen and urobilinogen form a red-colored compound with Ehrlich's
reagent. How can they be differentiated? - ANSWER Urobilinogen is soluble in
chloroform
Prehepatic bilirubin has which of the following for a carrier? - ANSWER Albumin
Direct-reacting bilirubin is also known as what substance? - ANSWER Bilirubin
diglucaronide
An increase in indirect-reacting bilirubin is suggestive of which condition? - ANSWER
, Hemoglobin breakdown
Bilirubin is converted in the intestine to which of the following substances? - ANSWER
Urobilinogen
Which of the following will interfere with the Evelyn Malloy method for bilirubin? -
ANSWER Hemolysis
Which precaution should be followed in regard to specimen handling instructions for
bilirubin determinations? - ANSWER Protect from light
Which one of the following definitions best describes an enzyme? - ANSWER Biologic
catalyst
Which of the following is true of an isoenzyme? - ANSWER The electrophoretic
property is different for each isoenzyme
Why is a metal ion sometimes necessary in an enzymatic reaction? - ANSWER Acts as
an activator of the enzyme
The Michaelis-Menton constant in the rate of conversion of substrate to product is
determined by what factor? - ANSWER Substrate concentration and the rate of
dissociation of the complex
In a zero-order reaction, there will be no further increase in velocity due to which one of
the following? - ANSWER All enzyme is bound to substrate
What is the reporting unit of measure for enzymes? - ANSWER IU/L
Which enzyme catalyzes this reaction? lactate + NAD -> pyruvate + NADH - ANSWER
Lactate dehydrogenase
Which of the following is true of the isoenzyme LD1? - ANSWER It is present in the
highest concentration in the hear muscle
Which enzyme is most greatly affected by hemolysis? - ANSWER Lactate
dehydrogenase
An LD isoenzyme electrophoretic pattern that shows an increase in LD1, LD2, and LD3
is seen in which disease state? - ANSWER Pernicious anemia
Creatine kinase is clinically significant in diseases of which organ? - ANSWER Muscle
Creatine kinase is frequently elevated in acute myocardial infarction and which other
disorder? - ANSWER Duchenne's muscular dystrophy