Urine culture with UTI
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100.000 colonies in asymptomatic: bacteruria
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10 - 10.000 colonies in symptomatic patients but also pyuria
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pyuria: more than 10 leukocytes
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elevated erythrocytes with pyelonephritis
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WBC in urine|\ |\
false positive with tumor, urethritis and poor collection technique
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Repeat in pregnant women |\ |\ |\
Lower urinary tract UTI and upper urinary tract UTI
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bladder and urethra: cystitis/ urethritis/ prostatitis
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kidney and ureters: pyelonephritis/ renal abcess
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Uncomplicated and complicated uti |\ |\ |\
Uncomplicated: in normal working urinary tract |\ |\ |\ |\ |\
Complicated: defects in urinary tract or with other health |\ |\ |\ |\ |\ |\ |\ |\ |\
problems
,Common pathogens for UTI |\ |\ |\
E.coli (elderly women)
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Staphylococcus
proteus mirabilis (elderly men)
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Klebsiella
enterecoccus
pseudomonas
Providencia (institutionalized) |\
Fungus: candida |\
Risk factors for UTI
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Female
critically ill |\
elderly
catheter (caused by biofilm) |\ |\ |\
DM
calculi, tumor, stricture
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neurogenic bladder |\
Women:
sexual intercourse or new sex partner
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pregnancy
previous UTI |\
,Men:
prostate enlargement |\
prostatitis
lack of circumcision
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gay
HIV
Findings UTI |\
Lower:
Dysuria/ urgency/ frequency/ incontinence
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suprapubic pain |\
hematuria
fever/ chills uncommon
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No flank pain
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Upper:
flank pain |\
fever and chills
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hematuria
n/v
ams (in elderly)
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malaise
tachycardia/ tachypnea |\
, Testing and results for UTI |\ |\ |\ |\
Gold standard: urine culture and sensitivity: detection of bacteria.
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Start with POC: urine analysis.
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UA: pos for nitrite or leukocyte or blood
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CBC: leukocyte with left shift in pyelonephritis
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For recurrent UTI in women or UTI in men rule out obstruction,
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calculi, or necrosis with: |\ |\ |\
xr voiding|\
CT abdomen |\
US pelvis |\
MRI pelvis |\
Management acute cystitis |\ |\
First line: |\
- Single dose Fosfomycin (monurol)
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- 3 day: sulfa: trimethoprim/ sulfa (bactrim) (do not give near
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delivery of baby, give cephalexin instead) or sulfa|\ |\ |\ |\ |\ |\ |\
- 5 days: nitrofurantoin, caution in elderly
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Second line: |\
- qiunolones: ciprofloxain or levofloxacin for 3 days (not for
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pregnant women!) |\