NR-566: Advanced Pharmacology for Care of the
Family Final Exam - Chamberlain University
2025/2026 | Questions and Correct Answers |
Latest Version | Verified Solution 100%
Why do men have higher hematocrit levels than women?
They produce more testosterone which results in higher amounts of erythropoietin and erythrocytes.
What is the Black Box warning for the androgen Oxandrolone? anabolic steroid
Can cause peliosis hepatitis; blood-filled cysts form in the liver leading to failure or intrabdominal
hemorrhage
What are the disorders that the androgen testosterone can treat?
Hypogonadism (male), replacement therapy
What are the disorders that the androgen methyltestosterone can treat? Male Hormone
Replacement and hypogonadism in males
What are the disorders that the androgen oxandrolone can treat? anabolic steroid
Catabolic states (cachexia)
Testosterone can be used to treat what symptoms in post-menopausal women?
Reduced genital sensitivity, fatigue, and decreased libido
What hormones does androgens suppress?
Luteinizing and follicle-stimulating
Which particle in the life cycle of chlamydia trachomatis is considered infectious and first infects the
host cell?
elementary body
What is the recommended testing for males suspected to have Chlamydia?
first-catch urine for nucleic acid amplification test (NAAT)
What are the CDC screening recommendations for chlamydia in asymptomatic females?
annual screening annually in sexually active females 24 years or younger.
,What is the recommend treatment for uncomplicated chlamydia in non-pregnant females and males?
doxycycline 100mg by mouth twice daily x7 days (alternate azithromycin 1g by mouth x1)
What is the mechanism of action of donepezil (Aricept)? Alzheimer's disease
inhibits centrally active acetylcholinesterase
What are the common side effects of Aricept? Alzheimer's disease
gastrointestinal symptoms (nausea and diarrhea), headache, dizziness, muscle weakness
List the precautions for Aricept? Alzheimer's disease
sick sinus syndrome and seizure disorder
When combined with _________ and __________ peripheral side effects and rate of elimination can
be increased for Aricept? Alzheimer's disease
CYP2D6 & CYP3A4
What is the mechanism of action of Rivastigmine (Exelon)? mild to moderate dementia (memory loss
and mental changes) associated with Alzheimer's disease or Parkinson's disease
acts centrally for both acetylcholinesterase and butyrylcholinesterase, thereby potentially increasing its
efficacy
What are some common side effects of Exelon? mild to moderate dementia (memory loss and mental
changes) associated with Alzheimer's disease or Parkinson's disease
GI symptoms, weakness, dizziness, tremor
What are some precautions to keep in mind with prescribing Exelon? mild to moderate dementia
(memory loss and mental changes) associated with Alzheimer's disease or Parkinson's disease
Asthma/COPD, sick sinus syndrome, GI bleed, weight less than 50 kg
The Exelon transdermal patch is used for dementia associated with ____________.
Parkinson's disease
What are the 2 major metabolizing enzymes that increase galantamine (Razadyne)
concentrations? Dementia
CYP3A4 and CYP2D6
What is the mechanism of action of galantamine (Razadyne)? Dementia
elevating acetylcholine (Ach) in the cerebral cortex, modulating the nicotinic Ach receptors to increase
Ach release from existing presynaptic nerve terminals. Increases glutamate and serotonin levels
What are the common side effects of galantamine (Razadyne)? Dementia
GI symptoms, headache, dizziness, fatigue
,What are the prescription precautions for galantamine (Razadyne)? Dementia
NSAID use, GI bleed, asthma or COPD, concurrent use with meds that decrease heart rate
What are contraindications for use of Galantamine (Razadyne)? Dementia
severe liver or renal impairment
What is the only N-methyl-D-aspartate (NMDA) approved to treat moderate to severe Alzheimer's
disease? Dementia
Memantine (Namenda)
What is the mechanism of action of memantine (Namenda) Dementia
prevents overactivation of glutamine receptors
What are the common side effects of memantine (Namenda)? Dementia
gastrointestinal symptoms (constipation, diarrhea, and weight gain), urinary frequency, confusion,
dizziness, headache, cough
What are the prescribing precautions for nemantine (Namenda)? Dementia
concurrent use with amantadine, rimantadine, ketamine, or dextromethorphan and severe renal or
hepatic impairment
An increased risk for ____________ can occur when memantine (Namenda) is given with a
cholinesterase Inhibitor? Dementia
Falls; do not drive due to delayed reactions
Drugs that treat Alzheimer's disease work on all patients and cure AD?
False
Which AD drug requires tapering when discontinuing the drug?
donepezil
What gender is most at risk for Alzheimer's?
female
What is the recommended start dose for rivastigmine to treat AD?
1.5mg by mouth twice daily
Why are acetylcholinesterase inhibitors a problem for those with COPD?
the can increase acetylcholine at the synapses in the lungs leading to bronchoconstriction
What is the most effective drug for Parkinson's disease?
levodopa
, Which 2 antipsychotics have demonstrated a reduction in neuropsychiatric symptoms with their use?
risperidone, olanzapine (schizophrenia)
Selegiline is contraindicated with which drugs? Parkinson disease and a major depressive disorder in
adults
SSRI's; can cause fatal serotonin syndrome
What percentage of people globally are impacted by mental health disorders, neurological, and
substance use disorders?
30%
What percentage of children and adolescents are impacted by mental health disorders worldwide?
20%
What 3 major drug classes treat bipolar disease?
mood stabilizers, antipsychotics, antidepressants
What class of drugs is contraindicated in someone taking lithium because they can increase lithium
levels by as much as 60%? (schizophrenia)
NSAIDs (i.e. Ibuprofen)
What are the signs of lithium toxicity? (schizophrenia)
nausea, vomiting, tremor, confusion, blurred vision, and tinnitus
What is the ideal level of lithium in the bloodstream? (schizophrenia)
0.6-0.8
Lithium levels greater than ___________ can produce significant toxicity. (schizophrenia)
1.5
How long must a patient be on an antidepressant in order to determine it's effectiveness?
4-8 weeks
What is the goal of antidepressant treatment?
remission of symptoms
What is the mechanism of action for SSRIs?
inhibits reuptake of serotonin
What is the mechanism of action for SNRIs.
(Cymbalta
Desvenlafaxine
Family Final Exam - Chamberlain University
2025/2026 | Questions and Correct Answers |
Latest Version | Verified Solution 100%
Why do men have higher hematocrit levels than women?
They produce more testosterone which results in higher amounts of erythropoietin and erythrocytes.
What is the Black Box warning for the androgen Oxandrolone? anabolic steroid
Can cause peliosis hepatitis; blood-filled cysts form in the liver leading to failure or intrabdominal
hemorrhage
What are the disorders that the androgen testosterone can treat?
Hypogonadism (male), replacement therapy
What are the disorders that the androgen methyltestosterone can treat? Male Hormone
Replacement and hypogonadism in males
What are the disorders that the androgen oxandrolone can treat? anabolic steroid
Catabolic states (cachexia)
Testosterone can be used to treat what symptoms in post-menopausal women?
Reduced genital sensitivity, fatigue, and decreased libido
What hormones does androgens suppress?
Luteinizing and follicle-stimulating
Which particle in the life cycle of chlamydia trachomatis is considered infectious and first infects the
host cell?
elementary body
What is the recommended testing for males suspected to have Chlamydia?
first-catch urine for nucleic acid amplification test (NAAT)
What are the CDC screening recommendations for chlamydia in asymptomatic females?
annual screening annually in sexually active females 24 years or younger.
,What is the recommend treatment for uncomplicated chlamydia in non-pregnant females and males?
doxycycline 100mg by mouth twice daily x7 days (alternate azithromycin 1g by mouth x1)
What is the mechanism of action of donepezil (Aricept)? Alzheimer's disease
inhibits centrally active acetylcholinesterase
What are the common side effects of Aricept? Alzheimer's disease
gastrointestinal symptoms (nausea and diarrhea), headache, dizziness, muscle weakness
List the precautions for Aricept? Alzheimer's disease
sick sinus syndrome and seizure disorder
When combined with _________ and __________ peripheral side effects and rate of elimination can
be increased for Aricept? Alzheimer's disease
CYP2D6 & CYP3A4
What is the mechanism of action of Rivastigmine (Exelon)? mild to moderate dementia (memory loss
and mental changes) associated with Alzheimer's disease or Parkinson's disease
acts centrally for both acetylcholinesterase and butyrylcholinesterase, thereby potentially increasing its
efficacy
What are some common side effects of Exelon? mild to moderate dementia (memory loss and mental
changes) associated with Alzheimer's disease or Parkinson's disease
GI symptoms, weakness, dizziness, tremor
What are some precautions to keep in mind with prescribing Exelon? mild to moderate dementia
(memory loss and mental changes) associated with Alzheimer's disease or Parkinson's disease
Asthma/COPD, sick sinus syndrome, GI bleed, weight less than 50 kg
The Exelon transdermal patch is used for dementia associated with ____________.
Parkinson's disease
What are the 2 major metabolizing enzymes that increase galantamine (Razadyne)
concentrations? Dementia
CYP3A4 and CYP2D6
What is the mechanism of action of galantamine (Razadyne)? Dementia
elevating acetylcholine (Ach) in the cerebral cortex, modulating the nicotinic Ach receptors to increase
Ach release from existing presynaptic nerve terminals. Increases glutamate and serotonin levels
What are the common side effects of galantamine (Razadyne)? Dementia
GI symptoms, headache, dizziness, fatigue
,What are the prescription precautions for galantamine (Razadyne)? Dementia
NSAID use, GI bleed, asthma or COPD, concurrent use with meds that decrease heart rate
What are contraindications for use of Galantamine (Razadyne)? Dementia
severe liver or renal impairment
What is the only N-methyl-D-aspartate (NMDA) approved to treat moderate to severe Alzheimer's
disease? Dementia
Memantine (Namenda)
What is the mechanism of action of memantine (Namenda) Dementia
prevents overactivation of glutamine receptors
What are the common side effects of memantine (Namenda)? Dementia
gastrointestinal symptoms (constipation, diarrhea, and weight gain), urinary frequency, confusion,
dizziness, headache, cough
What are the prescribing precautions for nemantine (Namenda)? Dementia
concurrent use with amantadine, rimantadine, ketamine, or dextromethorphan and severe renal or
hepatic impairment
An increased risk for ____________ can occur when memantine (Namenda) is given with a
cholinesterase Inhibitor? Dementia
Falls; do not drive due to delayed reactions
Drugs that treat Alzheimer's disease work on all patients and cure AD?
False
Which AD drug requires tapering when discontinuing the drug?
donepezil
What gender is most at risk for Alzheimer's?
female
What is the recommended start dose for rivastigmine to treat AD?
1.5mg by mouth twice daily
Why are acetylcholinesterase inhibitors a problem for those with COPD?
the can increase acetylcholine at the synapses in the lungs leading to bronchoconstriction
What is the most effective drug for Parkinson's disease?
levodopa
, Which 2 antipsychotics have demonstrated a reduction in neuropsychiatric symptoms with their use?
risperidone, olanzapine (schizophrenia)
Selegiline is contraindicated with which drugs? Parkinson disease and a major depressive disorder in
adults
SSRI's; can cause fatal serotonin syndrome
What percentage of people globally are impacted by mental health disorders, neurological, and
substance use disorders?
30%
What percentage of children and adolescents are impacted by mental health disorders worldwide?
20%
What 3 major drug classes treat bipolar disease?
mood stabilizers, antipsychotics, antidepressants
What class of drugs is contraindicated in someone taking lithium because they can increase lithium
levels by as much as 60%? (schizophrenia)
NSAIDs (i.e. Ibuprofen)
What are the signs of lithium toxicity? (schizophrenia)
nausea, vomiting, tremor, confusion, blurred vision, and tinnitus
What is the ideal level of lithium in the bloodstream? (schizophrenia)
0.6-0.8
Lithium levels greater than ___________ can produce significant toxicity. (schizophrenia)
1.5
How long must a patient be on an antidepressant in order to determine it's effectiveness?
4-8 weeks
What is the goal of antidepressant treatment?
remission of symptoms
What is the mechanism of action for SSRIs?
inhibits reuptake of serotonin
What is the mechanism of action for SNRIs.
(Cymbalta
Desvenlafaxine
