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Chapter 2.1 Metabolism
- Metabolism
o refers to all chemical reactions occurring within a Cell
- Catabolic and Anabolic Pathways o Catabolic: how we generate energy and get the
building blocks for the cells to build molecules they need to carry out their daily
functions.
Able to generate forms of energy.
Catabolic and Anabolic Pathways
Catabolic Pathways Anabolic Pathways All Metabolic Pathways
Breakdown of molecules Building molecules Tightly regulated (occur
only as needed)
Overall release energy Overall consume energy Necessary for cell survival
Rely on oxidized Rely on reduced Require enzymes
coenzymes (especially coenzymes (especially
NAD+) to oxidize NADPH) to reduce
intermediates intermediates
Example: Cellular Example lipid biosynthesis
respiration
- Enzymes
o A protein that catalyzes a specific chemical reaction
- Catalysis
o Acceleration of a reaction by making it. More energetically favorable o Lower
the activation energy
- Cofactor
o Metal ions that activate or enhance enzyme activity (Ca2+, Zn2+)
- Substrate o The target of the enzyme ENZYME
- As a protein, an enzyme’s structure is dictated by the DNA sequence that encodes for it.