BIO 203
Cellular and Organ
2 K+ 3 Na+
Physiology
ATP ADP + Pi
2 K+ 3 Na+
Respiratory Systems II
Dr. Robert Watson
Neurobiology & Behavior
Stony Brook University
, Learning Objectives
1. Explain the differences between lung volumes and lung
capacities
a) Explain the importance of dead space with respect to alveolar
ventilation
2. Compare and contrast the transport of O2 and CO2 in
blood
3. Understand the O2-Hb dissociation curve and factors that
can shift the curve
a) Describe the importance of P50
4. Compare and contrast hemoglobin and myoglobin
5. Explain the role of CO2 in controlling ventilation rate
6. Describe the general characteristics of asthmatic airways
7. Explain how fluticasone, salmeterol, and albuterol can be
useful in the therapeutic management of asthma
, Measuring Lung Function
The Spirometer
This figure shows a traditional wet spirometer. The subject inserts a mouthpiece
that is attached to an inverted bell filled with air or oxygen. The volume of the
bell and the volume of the subject’s respiratory
tract create a closed system because the
bell is suspended in water.
Bell
Inspiration Expiration Inspiration
0.5
Air
Volume
(L)
Water 0
Time
Upon inspiration, air moves into the lungs.
The volume of the bell decreases, and the
pen rises on the tracing.
Human Physiology (Silverthorn) © 2019 Pearson Education Inc.
, Lung Volumes and Capacities
5800
End of
normal Inspiratory Inspiratory
inspiration capacity
reserve
volume
Volume 3000 mL
(mL) Tidal Vital
volume capacity
500 mL 4600 mL
2800 Total lung
Capacity
2300 5800 mL
End of Expiratory
normal reserve
expiration volume
1100 mL Functional
1200 residual
capacity
Residual volume
1200 mL
Human Physiology (Silverthorn) © 2019 Pearson Education Inc.
Time
Cellular and Organ
2 K+ 3 Na+
Physiology
ATP ADP + Pi
2 K+ 3 Na+
Respiratory Systems II
Dr. Robert Watson
Neurobiology & Behavior
Stony Brook University
, Learning Objectives
1. Explain the differences between lung volumes and lung
capacities
a) Explain the importance of dead space with respect to alveolar
ventilation
2. Compare and contrast the transport of O2 and CO2 in
blood
3. Understand the O2-Hb dissociation curve and factors that
can shift the curve
a) Describe the importance of P50
4. Compare and contrast hemoglobin and myoglobin
5. Explain the role of CO2 in controlling ventilation rate
6. Describe the general characteristics of asthmatic airways
7. Explain how fluticasone, salmeterol, and albuterol can be
useful in the therapeutic management of asthma
, Measuring Lung Function
The Spirometer
This figure shows a traditional wet spirometer. The subject inserts a mouthpiece
that is attached to an inverted bell filled with air or oxygen. The volume of the
bell and the volume of the subject’s respiratory
tract create a closed system because the
bell is suspended in water.
Bell
Inspiration Expiration Inspiration
0.5
Air
Volume
(L)
Water 0
Time
Upon inspiration, air moves into the lungs.
The volume of the bell decreases, and the
pen rises on the tracing.
Human Physiology (Silverthorn) © 2019 Pearson Education Inc.
, Lung Volumes and Capacities
5800
End of
normal Inspiratory Inspiratory
inspiration capacity
reserve
volume
Volume 3000 mL
(mL) Tidal Vital
volume capacity
500 mL 4600 mL
2800 Total lung
Capacity
2300 5800 mL
End of Expiratory
normal reserve
expiration volume
1100 mL Functional
1200 residual
capacity
Residual volume
1200 mL
Human Physiology (Silverthorn) © 2019 Pearson Education Inc.
Time
