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Exam (elaborations)

PANCE Antibiotics Review with Complete Solutions

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which class of abx is known for causing permanent SNHL?- aminoglycosides (esp. gentamicin) which antibiotic can cause transient (not permanent) vestibular dysfunction (SNHL)?- minocycline which antimicrobial is the most nephrotoxic?- amphoter

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PANCE Antibiotics
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PANCE Antibiotics

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Uploaded on
October 21, 2025
Number of pages
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Written in
2025/2026
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PANCE Antibiotics Review with Complete Solutions
which class of abx is known for causing
permanent SNHL?- aminoglycosides (esp. which abx is associated with a diffuse,
gentamicin) maculopapular, nonurticarial rash when given to
someone with EBV?- ampicillin

which antibiotic can cause transient (not
permanent) vestibular dysfunction (SNHL)?- metronidazole is pregnancy category B, except
minocycline when?- first trimester...fetotoxic


which antimicrobial is the most nephrotoxic?- which class of abx are associated with tendon
amphotericin B ruptures, esp Achilles tendon?-
flouroquinolones

which class of abx can cause acute tubular
necrosis (ATN)?- aminoglycosides (esp. which class of abx are very similar to penicillins
gentamicin) with regard to mechanism of action and allergic
reactions?- cephalosporins

which antibiotic is known for causing a
disulfuram-like reaction?- metronidazole if someone gets a rash from penicillin, you
(drinking a beer on the metro (subway)) wouldn't give them a penicillin, but you could
potentially give what class?- cephalosporin

which antibiotic causes Red Man Syndrome?-
Vancomycin (Van the Red Man) if someone has an anaphylactic reaction to PCN,
you wouldn't give a PCN or what other class?-
cephalosporin
which abx causes Red Lobster Syndrome?-
rifampin (Rifampin the Red lobster)
what is the MOA of PCN?- inhibits cell wall
synthesis
which class of abx causes teeth discoloration
and is contraindicated in children <8yo?-
tetracylines what are the 2 main organisms treated with PCN
in primary care?- s. pyogenes (group A
strep) and t. pallidum (syphilis)
which class of abx causes Yellow Babies by
displacing bilirubin?- sulfonamides
(Bactrim/Septra) what are the anti-staph penicillins?- nafcillin
(IV) and dicloxacillin (PO)
Naf rhymes with staph. He had a staph infxn on
which abx is most commonly associated with C. his DICk
Diff?- clindamycin

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, PANCE Antibiotics Review with Complete Solutions
which oral antibiotic would you use for a skin
abscess in which s. aureus is the suspected what are the oral 3rd generation
organism?- dicloxacillin cephalosporins?- cefpodoxime (vantin) and
cefdinir (omnicef)

which abx would you use to treat Lyme Disease
in a child under 8 y/o?- amoxicillin what are the 2nd generation cephalosporins
typically used for?- URTIs and soft tissue
infections
which abx would you use for endocarditis
prophylaxis prior to a dental procedure?-
amoxicillin what are the oral 3rd gen cephalosporins used
for?- URTIs and soft tissue infections
(similar indications as 2nd gen)
which abx would you use as prophylaxis or to
treat an animal or human bite?-
amoxicillin/clavulanate (augmentin) As generations of abx increase what happens to
coverage?- you lose gram pos coverage
and gain gram neg coverage
if you treated a sinus infection or otitis media with
amoxicillin and the patient did not get better,
which abx would you use next?- what is the parenteral/injectable 3rd gen
amoxicillin/clavulanate (augmentin) cephalosporin?- ceftriaxone


what is the MOA of cephalosporins?- inhibit what is the DOC for gonorrhea?-
cell wall synthesis ceftriaxone


what are the most common 1st generation which cephalosporin is used for meningitis?-
cephalosporins?- cefazolin (IV) and ceftriaxone
cephalexin (PO)

what are the 4th generation cephalosporins?-
which antibiotic would you use for perioperative ceftazidime and cefepime
prophylaxis?- cefazolin (ancef)

what is the 5th generation cephalosporin?-
which generation are the "respiratory" ceftaroline
cephalosporins?- 2nd generation

what is the only cephalosporin with MRSA
what are the 2nd generation "respiratory" coverage?- ceftaroline
cephalosporins?- cefuroxime

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