Answers
1. Define perfusion Perfusion = delivery of oxygenated blood and nutrients to tissues and
removal of waste products.
2. What happens if perfu- Inadequate tissue oxygenation ’tissue damage ’organ failure.
sion is impaired?
3. Which three com- Heart (pumps), blood vessels (carry blood), and blood (carries oxy-
ponents interact to gen/nutrients).
achieve perfusion?
4. During which cardiac Fills during diastole, ejects during systole.
phase does the heart
fill and eject blood?
5. What is cardiac output CO = amount of blood pumped per minute; normal range 4-8 L/min.
(CO) and the normal
range?
6. Formula for cardiac CO = HR × SV (heart rate × stroke volume).
output?
7. What is preload vs af- Preload = volume in ventricles at end of diastole.
terload? Afterload = resistance heart must pump against (measured as SVR).
8. How does systemic vas- ‘SVR (e.g., hypertension) increases afterload, making pumping harder
cular resistance (SVR) af-
fect afterload?
9. Does low or high car- poor perfusion?
diac output cause poor
perfusion?
10. What are four signs of
, Low cardiac output.
-Urine output <30 mL/hr (or <0.5-1
mL/kg/hr for children <30 kg)
-Cool, clammy skin
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