APEA- Endocrine Pharm
10 minutes prior to a meal
Aspart (NovoLog) should be administered:
10 minutes prior to a meal.
30 minutes prior to a meal.
30 minutes after a meal.
just before sleep.
15 minutes.
Maximum plasma concentrations of The maximum plasma concentration of glucagon, after intramuscular administration
glucagon, after intramuscular injection, are to a patient with severe hypoglycemia, are obtained in approximately 13 minutes
observed in approximately:
5 minutes.
15 minutes.
30 minutes.
45 minutes.
avoid contact with young children for several days.
Patients who receive radioiodine have the potential to expose their home and
Patients who are receiving radioiodine household contacts via saliva and urine due to radiation emitting from their body.
therapy for hyperthyroidism should be Patients must take radiation precautions for several days after treatment, avoiding
advised to: contact with young children and pregnant women.
avoid contact with young children for
several days.
avoid becoming pregnant during treatment
and for 12 months after treatment.
expect hair loss over the next 3 months.
monitor for laryngeal damage.
twice daily, within 1 hour prior to morning and evening meals.
Because of the mechanism of action, Patients should be instructed to administer exenatide (Byetta) within 60 minutes
patients should be instructed to administer prior to the morning and evening meal (or prior to the 2 main meals of the day).
exenatide (Byetta): Injections should be administered approximately =6 hours apart
daily at bedtime.
immediately following the largest meal of
the day.
twice daily, within 1 hour prior to morning
and evening meals.
at least 12 hours apart, regardless of
meals.
10 units of Humulin R U-500 is equal to 10 units on a U-500 insulin syringe.
When patients administer regular insulin
(Humulin R U-500), they should be taught: For safety, ONLY the U-500 syringe should be used. It is not recommended for use
5 units of Humulin R U-500 is equal to 10 in insulin pumps due to possibility of precipitation.
units on a U-100 insulin syringe.
10 units of Humulin R U-500 is equal to 5
units on a U-100 insulin syringe.
10 units of Humulin R U-500 is equal to 10
units on a U-500 insulin syringe.
it should only be used in an insulin pump.
APEA- Endocrine Pharm.pdf
, APEA- Endocrine Pharm
highly efficacious with moderate risk of hypoglycemia.
Because the effect of these 2 medications in combination is additive, together they
The combination of metformin
can potentially decrease A1C 2-4%. This is considered highly efficacious.
(Glucophage) and glyburide (Diabeta) for
the treatment of Type 2 diabetes is:
moderately efficacious with low risk of
hypoglycemia.
moderately efficacious with high risk of
hypoglycemia.
highly efficacious with moderate risk of
hypoglycemia.
highly efficacious with low risk of
hypoglycemia.
pediatric patients with Type 2 diabetes mellitus.
Insulin glargine (Lantus) is NOT indicated The FDA has not approved Lantus for use in children with Type 2 diabetes.
in the treatment of:
adults with Type 1 diabetes mellitus.
adults with Type 2 diabetes mellitus.
pediatric patients with Type 1 diabetes
mellitus.
pediatric patients with Type 2 diabetes
mellitus.
may be administered once or twice daily.
Insulin detemir (Levemir):
has a longer duration of action than insulin
glargine (Lantus).
may be used in insulin pumps.
may be administered once or twice daily.
is indicated as monotherapy for patients
with Type 1 diabetes mellitus.
2%
A 48-year-old patient is started on
metformin (Glucophage) for Type 2
diabetes (T2DM). The maximum expected
hemoglobin A1C reduction after initiation of
this medication is:
0.5%.
1%.
2%.
3%.
at meal time.
Due to the mechanism of action of When taken on an empty stomach they have a 56% bioavailability when absorbed
meglitinides used in the treatment of Type from the gastrointestinal tract. Bioavailability is reduced when taken with food; the
2 diabetes, they should be administered: maximum concentration decreases by 20%, therefore reducing the risk of
at meal time. hypoglycemia. They should be administered within 30 minutes of a meal or at
at bedtime. mealtime 2-4 times daily.
2 hours after a meal.
2 hours before the largest meal of the day.
Hypothyroidism
Which of the following side effects may be Methimazole (Tapazole) can cause hypothyroidism, necessitating routine monitoring
caused by methimazole (Tapazole)? of TSH and free T4 levels with adjustments in dosing to maintain a euthyroid state.
Osteoporosis Other serious adverse reactions to methimazole (Tapazole) may include bone
Anxiety marrow suppression, hepatotoxicity, exfoliative dermatitis, unexplained fever, lupus-
Hypothyroidism like syndrome and vasculitis.
Supraventricular tachycardia
APEA- Endocrine Pharm.pdf
10 minutes prior to a meal
Aspart (NovoLog) should be administered:
10 minutes prior to a meal.
30 minutes prior to a meal.
30 minutes after a meal.
just before sleep.
15 minutes.
Maximum plasma concentrations of The maximum plasma concentration of glucagon, after intramuscular administration
glucagon, after intramuscular injection, are to a patient with severe hypoglycemia, are obtained in approximately 13 minutes
observed in approximately:
5 minutes.
15 minutes.
30 minutes.
45 minutes.
avoid contact with young children for several days.
Patients who receive radioiodine have the potential to expose their home and
Patients who are receiving radioiodine household contacts via saliva and urine due to radiation emitting from their body.
therapy for hyperthyroidism should be Patients must take radiation precautions for several days after treatment, avoiding
advised to: contact with young children and pregnant women.
avoid contact with young children for
several days.
avoid becoming pregnant during treatment
and for 12 months after treatment.
expect hair loss over the next 3 months.
monitor for laryngeal damage.
twice daily, within 1 hour prior to morning and evening meals.
Because of the mechanism of action, Patients should be instructed to administer exenatide (Byetta) within 60 minutes
patients should be instructed to administer prior to the morning and evening meal (or prior to the 2 main meals of the day).
exenatide (Byetta): Injections should be administered approximately =6 hours apart
daily at bedtime.
immediately following the largest meal of
the day.
twice daily, within 1 hour prior to morning
and evening meals.
at least 12 hours apart, regardless of
meals.
10 units of Humulin R U-500 is equal to 10 units on a U-500 insulin syringe.
When patients administer regular insulin
(Humulin R U-500), they should be taught: For safety, ONLY the U-500 syringe should be used. It is not recommended for use
5 units of Humulin R U-500 is equal to 10 in insulin pumps due to possibility of precipitation.
units on a U-100 insulin syringe.
10 units of Humulin R U-500 is equal to 5
units on a U-100 insulin syringe.
10 units of Humulin R U-500 is equal to 10
units on a U-500 insulin syringe.
it should only be used in an insulin pump.
APEA- Endocrine Pharm.pdf
, APEA- Endocrine Pharm
highly efficacious with moderate risk of hypoglycemia.
Because the effect of these 2 medications in combination is additive, together they
The combination of metformin
can potentially decrease A1C 2-4%. This is considered highly efficacious.
(Glucophage) and glyburide (Diabeta) for
the treatment of Type 2 diabetes is:
moderately efficacious with low risk of
hypoglycemia.
moderately efficacious with high risk of
hypoglycemia.
highly efficacious with moderate risk of
hypoglycemia.
highly efficacious with low risk of
hypoglycemia.
pediatric patients with Type 2 diabetes mellitus.
Insulin glargine (Lantus) is NOT indicated The FDA has not approved Lantus for use in children with Type 2 diabetes.
in the treatment of:
adults with Type 1 diabetes mellitus.
adults with Type 2 diabetes mellitus.
pediatric patients with Type 1 diabetes
mellitus.
pediatric patients with Type 2 diabetes
mellitus.
may be administered once or twice daily.
Insulin detemir (Levemir):
has a longer duration of action than insulin
glargine (Lantus).
may be used in insulin pumps.
may be administered once or twice daily.
is indicated as monotherapy for patients
with Type 1 diabetes mellitus.
2%
A 48-year-old patient is started on
metformin (Glucophage) for Type 2
diabetes (T2DM). The maximum expected
hemoglobin A1C reduction after initiation of
this medication is:
0.5%.
1%.
2%.
3%.
at meal time.
Due to the mechanism of action of When taken on an empty stomach they have a 56% bioavailability when absorbed
meglitinides used in the treatment of Type from the gastrointestinal tract. Bioavailability is reduced when taken with food; the
2 diabetes, they should be administered: maximum concentration decreases by 20%, therefore reducing the risk of
at meal time. hypoglycemia. They should be administered within 30 minutes of a meal or at
at bedtime. mealtime 2-4 times daily.
2 hours after a meal.
2 hours before the largest meal of the day.
Hypothyroidism
Which of the following side effects may be Methimazole (Tapazole) can cause hypothyroidism, necessitating routine monitoring
caused by methimazole (Tapazole)? of TSH and free T4 levels with adjustments in dosing to maintain a euthyroid state.
Osteoporosis Other serious adverse reactions to methimazole (Tapazole) may include bone
Anxiety marrow suppression, hepatotoxicity, exfoliative dermatitis, unexplained fever, lupus-
Hypothyroidism like syndrome and vasculitis.
Supraventricular tachycardia
APEA- Endocrine Pharm.pdf
