With Correct Answers Updated 2026/2027
Graded A+.
A colon cancer screening study is being conducted in Burkeshire, England. Individuals 50 to
75 years old will be screened with the Hemoccult test. In this test, a stool sample is tested for
the presence of blood. The Hemoccult test has a sensitivity of 70% and a specificity of 75%.
If Burkeshire has a prevalence of 12/1,000 for colon cancer, what is the computed positive
predictive value of the Hemoccult test? - correct answer 3.3%
Primary prevention - correct answer Immunization, reducing exposure to a risk factor
Secondary prevention - correct answer Screening for breast cancer
Tertiary prevention - correct answer Rehabilitation after a surgical procedure
A physical examination was used to screen for breast cancer in 2,500 women with biopsy-
proven adenocarcinoma of the breast and in 5,000 age- and race-matched control women.
Results of the physical examination were positive, meaning that a mass was palpated in 1,800
cases and in 800 control women, all of whom showed no evidence of cancer at biopsy. The
sensitivity of the physical examination was ________ percent. - correct answer 72%
Preclinical disease - correct answer Disease that is not yet clinically apparent but will
progress to clinical disease
Persistent (chronic) disease - correct answer Disease that persists for years and sometimes for
one's lifetime
A research study reported a weighted Kappa statistic of Kappa = 0.86 between raters (Kappa
= 0.86). The reported Kappa statistic indicates ________. - correct answer
Herd Immunity - correct answer The resistance of a group of people to an attack by a disease
to which a large proportion of members of the group are immune
Incubation period - correct answer The interval from receipt of infection to the time of onset
of clinical illness
A screening test is used in the same way in two similar populations, but the proportion of
false-positive results among those who test positive in population A is lower than that among
, those who test positive in population B. The most likely explanation for this finding is
________. - correct answer the prevalence of disease is higher in population A
Age-adjusted death rates are used to: - correct answer Eliminate the effects of differences in
the age distributions of populations in comparing death rates
At an initial examination in Plymouth, Massachusetts, migraine headache was found in 5 of
1,000 men aged 30 to 35 years and in 10 of 1,000 women aged 30 to 35 years. The inference
that women have a two times greater risk of developing migraine headache then man in this
age group is ________. - correct answer incorrect, because of failure to distinguish between
incidence and prevalence
Based on this table, it was concluded that workers in Industry B are at higher risk of death
from respiratory system cancer than workers in Industry A. (Assume that the age distributions
of the workers in the two industries are nearly identical.) Which of the following statements
is true? - correct answer The conclusion reached may be incorrect because proportionate
mortality was used when cause-specific mortality rates were needed.
A program manager from an international health funding agency wants to identify regions
that would benefit from an intervention to reduce premature disability. The program manager
asks you to develop a proposal using an index that would assist in making this decision.
Which of the following would best serve this purpose to provide the needed information? -
correct answer Disability-adjusted life-years
Validity - correct answer The ability of a screening test to distinguish who has a disease and
who does not
Sensitivity - correct answer The proportion of people with the disease who have a positive
test
Specificity - correct answer the proportion of non-diseased people who are correctly
identified as negative by a screening test
Positive predictive value - correct answer The proportion of patients who test positive who
actually have the disease
For a disease such as pancreatic cancer, which is highly fatal and of short duration,
________. - correct answer incidence rates and mortality rates will be similar
In 2010, there were 4,500 deaths caused by lung disease in coal miners aged 20 to 64 years.
The expected number of deaths in this occupational group, based on age-specific death rates
from lung disease in all males aged 20 to 64 years, was 1,800 during 2010. What is the
standardized mortality ratio (SMR) for lung diseases in coal miners? - correct answer 2.5 or
250
John Snow used epidemiology in 1854 to trace the cause of deaths in London to ________. -
correct answer cholera