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Cellular Perfusion
-adequate cellular perfusion means...
1.) adequate circulation
2.) adequate cardiac output
3.) adequate vasomotor tone
-these allow us to meet the cellular demands and simultaneously remove waste
products efficiently
Another term for shock is inadequate delivery of oxygen to the cells.
Mean Arterial Pressure (MAP)
-the MAP is what drives cellular perfusion
-a normal MAP is 70 to 100
-ideally, we want a MAP that is >60 in order to adequately perfuse
Hypoperfusion/Shock
-without adequate perfusion, cells shift to anaerobic metabolism
^only 5% of energy is actually produced (1/18)
-the anaerobic metabolism leads to the production of lactic acid, leading to lactic
acidosis
Causes of Hypoperfusion/Shock
1. lactic acid is the most common cause of metabolic acidosis
2. DKA (due to profound diuresis)
3. uremia (development of sepsis)
, Heart's Relation to Shock
1. The Fluid (hypovolemic)
2. The Pump (cardiogenic)
3. The Pipes (distributive)
Hypovolemic Shock
-the most common cause of shock
-inadequate circulating volume
^can be caused by GI bleed, dehydration, etc.
-can also be a shift of fluid to the interstitial space (burn shock)
-can shift into the peritoneal space
^can see ascites
^we can see it in regard to liver failure, or blood can pool within the pelvic cavity after a
pelvic fracture
-it can also be in the retroperitoneal space
^in pancreatitis, up to 11 liters of fluid can shift
Early Hypovolemic Shock
As the body senses the organs are underperfused it...
-increases HR
-increases RR
-increases contractility
-vasoconstricts (increases venous return; causes cool, clammy skin)