Cancer immunotherapy Exam questions and
answers
What is a vaccine given as an immune stimulant after surgery for non-muscle invasive bladder cancer to
prevent progression to muscle invasive? - ✅✅BCG
What are immunotherapy drugs also known as? - ✅✅Immune checkpoint inhibitors
How do immune checkpoint inhibitors work? - ✅✅Block the regulatory "off switch" on T cells that
prevent them from attacking cancer cells
This allows the immune system to mount an appropriate response to cancer cells
What are 3 examples of targets of immune checkpoint inhibitors? - ✅✅CLTA4
PD1
PDL1
What is CTLA4? - ✅✅Cytotoxic T lymphocyte antigen 4
Where is CTLA4 expressed? - ✅✅T lymphocytes
What is PD1? - ✅✅Programmed cell death protein 1
What is PDL1? - ✅✅Programmed death ligand 1
How do most licensed immune checkpoint inhibitors work? - ✅✅Long acting monoclonal antibodies
that cause immune checkpoint blockage to release anti-tumour immunity
How is immunotherapy delivered? - ✅✅IV
, How is immunotherapy dosed? - ✅✅According to body weight
What are 5 examples of cancers where immunotherapy is used? - ✅✅Melanoma
Lung
Bladder
Head and neck
Kidney
What is the purpose of most immunotherapy? - ✅✅Palliative treatment
When can immunotherapy side effects occur? - ✅✅From the start of therapy until many months after
How does the consistency of side effects of immunotherapy differ from chemotherapy? -
✅✅Fluctuates in chemotherapy
Consistent in immunotherapy
When is the peak incidence of immunotherapy side effects? - ✅✅6-8 weeks after first treatment
Describe the most common rash seen as a side effect of immunotherapy - ✅✅Maculopapular eczema
type rash on trunk
What are 3 rarer types of rash seen as side effects of immunotherapy? - ✅✅Psoriatic plaques
Angioedema
Vitiligo
How are mild immunotherapy rashes treated? - ✅✅Topical emollients
Steroid creams
What is a rarer more serious immunotherapy rash? - ✅✅Stevens Johnson syndrome
answers
What is a vaccine given as an immune stimulant after surgery for non-muscle invasive bladder cancer to
prevent progression to muscle invasive? - ✅✅BCG
What are immunotherapy drugs also known as? - ✅✅Immune checkpoint inhibitors
How do immune checkpoint inhibitors work? - ✅✅Block the regulatory "off switch" on T cells that
prevent them from attacking cancer cells
This allows the immune system to mount an appropriate response to cancer cells
What are 3 examples of targets of immune checkpoint inhibitors? - ✅✅CLTA4
PD1
PDL1
What is CTLA4? - ✅✅Cytotoxic T lymphocyte antigen 4
Where is CTLA4 expressed? - ✅✅T lymphocytes
What is PD1? - ✅✅Programmed cell death protein 1
What is PDL1? - ✅✅Programmed death ligand 1
How do most licensed immune checkpoint inhibitors work? - ✅✅Long acting monoclonal antibodies
that cause immune checkpoint blockage to release anti-tumour immunity
How is immunotherapy delivered? - ✅✅IV
, How is immunotherapy dosed? - ✅✅According to body weight
What are 5 examples of cancers where immunotherapy is used? - ✅✅Melanoma
Lung
Bladder
Head and neck
Kidney
What is the purpose of most immunotherapy? - ✅✅Palliative treatment
When can immunotherapy side effects occur? - ✅✅From the start of therapy until many months after
How does the consistency of side effects of immunotherapy differ from chemotherapy? -
✅✅Fluctuates in chemotherapy
Consistent in immunotherapy
When is the peak incidence of immunotherapy side effects? - ✅✅6-8 weeks after first treatment
Describe the most common rash seen as a side effect of immunotherapy - ✅✅Maculopapular eczema
type rash on trunk
What are 3 rarer types of rash seen as side effects of immunotherapy? - ✅✅Psoriatic plaques
Angioedema
Vitiligo
How are mild immunotherapy rashes treated? - ✅✅Topical emollients
Steroid creams
What is a rarer more serious immunotherapy rash? - ✅✅Stevens Johnson syndrome
