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BIO N154 Midterm 2 Exam With Complete Solutions

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BIO N154
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October 15, 2025
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2025/2026
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BIO N154 Midterm 2 Exam With Complete Solutions


Ligand-gated (ionotropic) receptors have ___ channels as part of their structure -
ANSWER ion



What ions can flow through open ion-selective receptor channels? - ANSWER Na+/K+

Ca2+

Cl-



What is the Cl- concentration gradient? - ANSWER More Cl- outside



What is required to do PCR? - ANSWER 1. forward and reverse primers

2. DNA template

3. DNA polymerase

4. dNTPs

5. reaction buffer



site-directed mutagenesis - ANSWER Techniques used to modify a gene in a specific
location to produce the desired polypeptide



What are the 2 types of neurotransmitter receptors? - ANSWER 1. ligand-gated
(iontropic)

2. G-protein coupled



What are examples of iontropic receptors? - ANSWER 1. nicotinic acetylcholine
receptors (nAChR)

2. Glutamate receptor

-Kainate

, -NMDA

-AMPA

3. GABA receptor



ESPS - ANSWER An excitatory synapse is a synapse in which an action potential in a
presynaptic neuron increases the probability of an action potential occurring in a
postsynaptic cell.



ISPS - ANSWER inhibitory post synaptic potential



What is the sodium ion concentration gradient? - ANSWER Sodium is low inside the cell



What is the chloride ion concentration gradient? - ANSWER Chloride is low inside the
cell



What is the potassium ion concentration gradient? - ANSWER Potassium is high inside
the cell



What is the excitatory neurotransmitter? - ANSWER glutamate



What is the inhibitory neurotransmitter? - ANSWER GABA



If you have cation influx into the cell, what should you expect? - ANSWER Depolarization



If you have anion influx into the cell, what should you expect? - ANSWER
Hyperpolarization



What are nAChRs located? - ANSWER neuromuscular junction

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