, SECOND EDITION
CHEMOTHERAPY AND
IMMUNOTHERAPY
GUIDELINES AND RECOMMENDATIONS FOR PRACTICE
Edited by
MiKaela Olsen, DNP, APRN-CNS, AOCNS®, FAAN
Kristine B. LeFebvre, DNP, RN, NPD-BC, AOCN®
Suzanne L. Walker, PhD, CRNP, BC, AOCN®
Elizabeth Prechtel Dunphy, DNP, CRNP, BC, AOCN®
, SECOND EDITION
CHEMOTHERAPY AND
IMMUNOTHERAPY
GUIDELINES AND RECOMMENDATIONS FOR PRACTICE
Edited by
MiKaela Olsen, DNP, APRN-CNS, AOCNS®, FAAN
Kristine B. LeFebvre, DNP, RN, NPD-BC, AOCN®
Suzanne L. Walker, PhD, CRNP, BC, AOCN®
Elizabeth Prechtel Dunphy, DNP, CRNP, BC, AOCN®
Oncology Nursing Society
Pittsburgh, Pennsylvania
, ONS Publications Department
Publisher and Director of Publications: William A. Tony, BA, CQIA
Senior Editorial Manager: Sean Pieszak, BA
Acquisitions Editor: Dave Burns, BA
Staff Editor II: Andrew Petyak, BA
Staff Editor I: Casey S. Kennedy, BA
Design and Production Administrator: Dany Sjoen
Editorial Assistant: Kira Hall, BA
Copyright © 2023 by the Oncology Nursing Society. All rights reserved. No part of the material protected by this copyright may be reproduced or utilized
in any form, electronic or mechanical, including photocopying, recording, or by an information storage and retrieval system, without written permission
from the copyright owner. For information, visit www.ons.org/publications-journals/permissions-archives, or send an email to .
Cover illustration by George Schill.
First printing March 2023; second printing, June 2023; third printing, September 2023
Library of Congress Cataloging-in-Publication Data
Names: Olsen, MiKaela M., editor. | LeFebvre, Kristine B., editor. |
Walker, Suzanne (Suzanne L.), editor. | Dunphy, Elizabeth Prechtel,
editor. | Oncology Nursing Society, issuing body.
Title: Chemotherapy and immunotherapy guidelines and recommendations for
practice / edited by MiKaela Olsen, Kristine B. LeFebvre, Suzanne
Walker, and Elizabeth Prechtel Dunphy.
Description: Second edition. | Pittsburgh, Pennsylvania : Oncology Nursing
Society, [2022] | Includes bibliographical references and index. |
Identifiers: LCCN 2022057352 | ISBN 9781635930559 (paperback) | ISBN
9781635930566 (ebook)
Subjects: MESH: Neoplasms--nursing | Neoplasms--therapy | Antineoplastic
Agents--toxicity | Immunotherapy | Practice Guideline
Classification: LCC RC266 .C484 2022 | NLM WY 156 | DDC
616.99/40231--dc23/eng20230118
LC record available at https://lccn.loc.gov/2022057352
Publisher’s Note
This book is published by the Oncology Nursing Society (ONS). ONS neither represents nor guarantees that the practices described herein will, if fol-
lowed, ensure safe and effective patient care. The recommendations contained in this book reflect ONS’s judgment regarding the state of general knowledge
and practice in the field as of the date of publication. The recommendations may not be appropriate for use in all circumstances. Those who use this book
should make their own determinations regarding specific safe and appropriate patient care practices, taking into account the personnel, equipment, and
practices available at the hospital or other facility at which they are located. The editors and publisher cannot be held responsible for any liability incurred
as a consequence from the use or application of any of the contents of this book. Figures and tables are used as examples only. They are not meant to be
all-inclusive, nor do they represent endorsement of any particular institution by ONS. Mention of specific products and opinions related to those products
do not indicate or imply endorsement by ONS. Websites mentioned are provided for information only; the hosts are responsible for their own content and
availability. Unless otherwise indicated, dollar amounts reflect U.S. dollars.
ONS publications are originally published in English. Publishers wishing to translate ONS publications must contact ONS about licensing arrange-
ments. ONS publications cannot be translated without obtaining written permission from ONS. (Individual tables and figures that are reprinted or adapted
require additional permission from the original source.) Because translations from English may not always be accurate or precise, ONS disclaims any
responsibility for inaccuracies in words or meaning that may occur as a result of the translation. Readers relying on precise information should check the
original English version.
Printed in the United States of America
Innovation • Excellence • Advocacy • Inclusivity
CHEMOTHERAPY AND
IMMUNOTHERAPY
GUIDELINES AND RECOMMENDATIONS FOR PRACTICE
Edited by
MiKaela Olsen, DNP, APRN-CNS, AOCNS®, FAAN
Kristine B. LeFebvre, DNP, RN, NPD-BC, AOCN®
Suzanne L. Walker, PhD, CRNP, BC, AOCN®
Elizabeth Prechtel Dunphy, DNP, CRNP, BC, AOCN®
, SECOND EDITION
CHEMOTHERAPY AND
IMMUNOTHERAPY
GUIDELINES AND RECOMMENDATIONS FOR PRACTICE
Edited by
MiKaela Olsen, DNP, APRN-CNS, AOCNS®, FAAN
Kristine B. LeFebvre, DNP, RN, NPD-BC, AOCN®
Suzanne L. Walker, PhD, CRNP, BC, AOCN®
Elizabeth Prechtel Dunphy, DNP, CRNP, BC, AOCN®
Oncology Nursing Society
Pittsburgh, Pennsylvania
, ONS Publications Department
Publisher and Director of Publications: William A. Tony, BA, CQIA
Senior Editorial Manager: Sean Pieszak, BA
Acquisitions Editor: Dave Burns, BA
Staff Editor II: Andrew Petyak, BA
Staff Editor I: Casey S. Kennedy, BA
Design and Production Administrator: Dany Sjoen
Editorial Assistant: Kira Hall, BA
Copyright © 2023 by the Oncology Nursing Society. All rights reserved. No part of the material protected by this copyright may be reproduced or utilized
in any form, electronic or mechanical, including photocopying, recording, or by an information storage and retrieval system, without written permission
from the copyright owner. For information, visit www.ons.org/publications-journals/permissions-archives, or send an email to .
Cover illustration by George Schill.
First printing March 2023; second printing, June 2023; third printing, September 2023
Library of Congress Cataloging-in-Publication Data
Names: Olsen, MiKaela M., editor. | LeFebvre, Kristine B., editor. |
Walker, Suzanne (Suzanne L.), editor. | Dunphy, Elizabeth Prechtel,
editor. | Oncology Nursing Society, issuing body.
Title: Chemotherapy and immunotherapy guidelines and recommendations for
practice / edited by MiKaela Olsen, Kristine B. LeFebvre, Suzanne
Walker, and Elizabeth Prechtel Dunphy.
Description: Second edition. | Pittsburgh, Pennsylvania : Oncology Nursing
Society, [2022] | Includes bibliographical references and index. |
Identifiers: LCCN 2022057352 | ISBN 9781635930559 (paperback) | ISBN
9781635930566 (ebook)
Subjects: MESH: Neoplasms--nursing | Neoplasms--therapy | Antineoplastic
Agents--toxicity | Immunotherapy | Practice Guideline
Classification: LCC RC266 .C484 2022 | NLM WY 156 | DDC
616.99/40231--dc23/eng20230118
LC record available at https://lccn.loc.gov/2022057352
Publisher’s Note
This book is published by the Oncology Nursing Society (ONS). ONS neither represents nor guarantees that the practices described herein will, if fol-
lowed, ensure safe and effective patient care. The recommendations contained in this book reflect ONS’s judgment regarding the state of general knowledge
and practice in the field as of the date of publication. The recommendations may not be appropriate for use in all circumstances. Those who use this book
should make their own determinations regarding specific safe and appropriate patient care practices, taking into account the personnel, equipment, and
practices available at the hospital or other facility at which they are located. The editors and publisher cannot be held responsible for any liability incurred
as a consequence from the use or application of any of the contents of this book. Figures and tables are used as examples only. They are not meant to be
all-inclusive, nor do they represent endorsement of any particular institution by ONS. Mention of specific products and opinions related to those products
do not indicate or imply endorsement by ONS. Websites mentioned are provided for information only; the hosts are responsible for their own content and
availability. Unless otherwise indicated, dollar amounts reflect U.S. dollars.
ONS publications are originally published in English. Publishers wishing to translate ONS publications must contact ONS about licensing arrange-
ments. ONS publications cannot be translated without obtaining written permission from ONS. (Individual tables and figures that are reprinted or adapted
require additional permission from the original source.) Because translations from English may not always be accurate or precise, ONS disclaims any
responsibility for inaccuracies in words or meaning that may occur as a result of the translation. Readers relying on precise information should check the
original English version.
Printed in the United States of America
Innovation • Excellence • Advocacy • Inclusivity
