MMSC423 Exam 2
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1. What is meant by the term primary fibrinolysis?
plasmin is formed in the presence of coagulation
plasmin is formed in the absence of coagulation
thrombin is formed in the absence of coagulation
formation of thrombin but absence of plasmin: plasmin is formed in the absence of coagula-
tion
2. Which of the following is a vitamin K antagonist?
warfarin
heparin
Plavix
DDAVP: heparin
3. What reagent is required when performing a specific factor assay?
factor deficient plasma
platelet agonist
vitamin K
barium sulfate: platelet agonist
4. What strongly immunogenic antigen is associated with isoimmune neonatal
thrombocytopenia?
PL A1
P
D
Csa: PL A1
5. In this test, sodium citrate whole blood is placed inside of an analyzer and
exposed to cartridges containing either collagen/epinephrine or collagen/ADP
to assess platelet aggregating ability
Prothrombin Time
PFA-100
APC resistance
Bleeding Time: PFA-100
6. Calculate the INR given the following results: patient PT = 12.5 seconds,
control = 11.6 seconds, ISI = 2.1
3.0
, MMSC423 Exam 2
Study online at https://quizlet.com/_htiodu
1.2
1.7
2.0: 1.2
7. The LMWHs are more efficient in binding factor ----------- than binding FIIa.
FXIIa
FXa
FVa
FVIIa: FXa
8. In this type of coagulation methodology, a stationary electrode and moving
electrode conduct electrical current when the fibrin clot is formed
optical
chromogenic
electromechanical
nephelometry: electromechanical
9. Which of the following is used to reverse the effects of heparin?
Coumadin
Aspirin
Vitamin K
protamine sulfate: protamine sulfate
10. In which disease state might you expect percent transmittance to be de-
creased in platelet aggregation studies with ADP?
von Willebrand's disease
Hemophilia A
Hemophilia B
Glanzmann's Thrombasthenia: Glanzmann's Thrombasthenia
11. What is the longest time a prothrombin time can be performed after collec-
tion if stored at 2-4 degrees Celsius or room temperature?
4 hours
8 hours
12 hours
24 hours: 24 hours
, MMSC423 Exam 2
Study online at https://quizlet.com/_htiodu
12. Which of the following is paramount to unfractionated heparin's efficacy as
a anticoagulant?
prothrombin
fibrinogen
antithrombin
prekallikrein: antithrombin
13. What is effective in reversing the effects of warfarin?
vitamin K
heparin
Coumadin
protamine sulfate: vitamin K
14. Which of the following tests is increased in a patient with severe hemophilia
A?
Thrombin Time
APTT
Factor VIII assay
PT: APTT
15. What is the significance behind the "Gray Platelet Syndrome" name?
- patients present with moderate thrombocytosis
- large platelets appear gray on Wright Stained blood smears
- red blood cells appear gray on Wright stained blood smears
- patients present with hemarthrosis: large platelets appear gray on Wright Stained blood smears
16. Why is Calcium chloride added after the FXII activator in the APTT?
- activator is added first to activate FXII and calcium is added second to activate
FX
- activator is added first to activate FXII, calcium is added second to activate
FXI
You Answered
- activator is added first to activate FXII, calcium is added second to activate
FVII
- activator is added first to activate FXII, calcium is added second to activate
FIX: activator is added first to activate FXII, calcium is added second to activate FIX
Study online at https://quizlet.com/_htiodu
1. What is meant by the term primary fibrinolysis?
plasmin is formed in the presence of coagulation
plasmin is formed in the absence of coagulation
thrombin is formed in the absence of coagulation
formation of thrombin but absence of plasmin: plasmin is formed in the absence of coagula-
tion
2. Which of the following is a vitamin K antagonist?
warfarin
heparin
Plavix
DDAVP: heparin
3. What reagent is required when performing a specific factor assay?
factor deficient plasma
platelet agonist
vitamin K
barium sulfate: platelet agonist
4. What strongly immunogenic antigen is associated with isoimmune neonatal
thrombocytopenia?
PL A1
P
D
Csa: PL A1
5. In this test, sodium citrate whole blood is placed inside of an analyzer and
exposed to cartridges containing either collagen/epinephrine or collagen/ADP
to assess platelet aggregating ability
Prothrombin Time
PFA-100
APC resistance
Bleeding Time: PFA-100
6. Calculate the INR given the following results: patient PT = 12.5 seconds,
control = 11.6 seconds, ISI = 2.1
3.0
, MMSC423 Exam 2
Study online at https://quizlet.com/_htiodu
1.2
1.7
2.0: 1.2
7. The LMWHs are more efficient in binding factor ----------- than binding FIIa.
FXIIa
FXa
FVa
FVIIa: FXa
8. In this type of coagulation methodology, a stationary electrode and moving
electrode conduct electrical current when the fibrin clot is formed
optical
chromogenic
electromechanical
nephelometry: electromechanical
9. Which of the following is used to reverse the effects of heparin?
Coumadin
Aspirin
Vitamin K
protamine sulfate: protamine sulfate
10. In which disease state might you expect percent transmittance to be de-
creased in platelet aggregation studies with ADP?
von Willebrand's disease
Hemophilia A
Hemophilia B
Glanzmann's Thrombasthenia: Glanzmann's Thrombasthenia
11. What is the longest time a prothrombin time can be performed after collec-
tion if stored at 2-4 degrees Celsius or room temperature?
4 hours
8 hours
12 hours
24 hours: 24 hours
, MMSC423 Exam 2
Study online at https://quizlet.com/_htiodu
12. Which of the following is paramount to unfractionated heparin's efficacy as
a anticoagulant?
prothrombin
fibrinogen
antithrombin
prekallikrein: antithrombin
13. What is effective in reversing the effects of warfarin?
vitamin K
heparin
Coumadin
protamine sulfate: vitamin K
14. Which of the following tests is increased in a patient with severe hemophilia
A?
Thrombin Time
APTT
Factor VIII assay
PT: APTT
15. What is the significance behind the "Gray Platelet Syndrome" name?
- patients present with moderate thrombocytosis
- large platelets appear gray on Wright Stained blood smears
- red blood cells appear gray on Wright stained blood smears
- patients present with hemarthrosis: large platelets appear gray on Wright Stained blood smears
16. Why is Calcium chloride added after the FXII activator in the APTT?
- activator is added first to activate FXII and calcium is added second to activate
FX
- activator is added first to activate FXII, calcium is added second to activate
FXI
You Answered
- activator is added first to activate FXII, calcium is added second to activate
FVII
- activator is added first to activate FXII, calcium is added second to activate
FIX: activator is added first to activate FXII, calcium is added second to activate FIX
