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limit alcohol/sun; increase dietary K+; report ototoxicity
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1 Goal of Antibacterial Drugs 2 Adverse Effects of Vancomycin
3 Vancomycin Administration 4 Loop Diuretics Teaching
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Terms in this set (188)
Goal of Antibacterial Kill bacteria or stop reproduction without harming
Drugs the patient.
Spectrum of Antibacterial Spectrum ≠ 'stronger'; match drug to bug (use
Drugs culture & sensitivity).
, Intended Response of Disappearance of s/s of infection (fever ↓, WBC
Antibacterial Drugs normalizing, drainage ↓).
Common Side Effects of Diarrhea, thrush/vaginal yeast.
Antibacterial Drugs
Adverse Effects of Allergy/anaphylaxis; C. difficile risk.
Antibacterial Drugs
Cell Wall Synthesis Bactericidal agents that inhibit bacterial cell wall
Inhibitors synthesis.
Penicillins Example: amoxicillin.
Cephalosporins Examples: cefazolin, cephalexin.
Monobactams Example: aztreonam.
Carbapenems Example: imipenem/cilastatin.
Glycopeptide Example: vancomycin.
Allergy Risk with Cell Allergy ↑ (cross‑sensitivity: penicillin ↔
Wall Inhibitors cephalosporins).
Adverse Effects of N/V, fever/chills, 'red man syndrome,' hearing ↓,
Vancomycin kidney function ↓; CNS changes, nephrotoxicity.
Administration of Give vancomycin SLOWLY.
Vancomycin
Teaching for Cephalosporins ≥1 hr before or ≥4 hr after
Cephalosporins iron/antacids.
Pediatric Considerations Reserve stronger agents for serious infections.
for Antibacterial Drugs
Penicillins/most cephalosporins low risk;
Pregnancy/Breastfeeding
carbapenems/monobactams/vanco
Considerations
low‑to‑moderate; all may be excreted in milk.
Older Adults Ototoxicity/nephrotoxicity more likely.
Considerations
Aminoglycosides Examples: amikacin, gentamicin, streptomycin.
Common Side Effects of N/V, rash, fever, lethargy.
Aminoglycosides