334 Immunity: Anaphylaxis Exam Questions And
Answers 100% Correct
hypersensitivities - ANSWER • Overactive immunity with excessive inflammation in
response to an antigen which the person usually has been previously exposed to.
• Spectrum of response:
- Uncomfortable: itchy, watery eyes, sneezing
- Life threatening: allergic asthma, angioedema, anaphylaxis, bronchoconstriction
4 Types:
• Type I: IgE antibody reaction. Rapid or Immediate (hay fever, asthma, anaphylaxis,
angioedema)
• Type 2: Cytotoxic, IgG reaction. Autoimmune hemolytic anemia.
• Type 3: Immune complex mediated: SLE, RA
• Type 4: Delayed reaction, T cell involved. Poison ivy, Positive TB skin test
Type 1 hypersensitivity - ANSWER • AKA "allergies" or "atopic allergies"
• Increased production of IgE antibody in response to the allergen (antigen)
• Acute inflammation occurs, locally or systemically and to
varying degrees (runny nose to anaphylaxis)
• Allergen exposure routes:
- Inhaled, Ingested, Injected, Skin or mucous membrane
Assessment - ANSWER • What are signs of inflammation?
• How do these manifest in allergic reactions?
• Histamine is the major driver of these responses.
• Severe: Anaphylaxis, Angioedema, Asthma (varied severity) • Less severe: Hay fever"
AKA allergic rhinitis
Answers 100% Correct
hypersensitivities - ANSWER • Overactive immunity with excessive inflammation in
response to an antigen which the person usually has been previously exposed to.
• Spectrum of response:
- Uncomfortable: itchy, watery eyes, sneezing
- Life threatening: allergic asthma, angioedema, anaphylaxis, bronchoconstriction
4 Types:
• Type I: IgE antibody reaction. Rapid or Immediate (hay fever, asthma, anaphylaxis,
angioedema)
• Type 2: Cytotoxic, IgG reaction. Autoimmune hemolytic anemia.
• Type 3: Immune complex mediated: SLE, RA
• Type 4: Delayed reaction, T cell involved. Poison ivy, Positive TB skin test
Type 1 hypersensitivity - ANSWER • AKA "allergies" or "atopic allergies"
• Increased production of IgE antibody in response to the allergen (antigen)
• Acute inflammation occurs, locally or systemically and to
varying degrees (runny nose to anaphylaxis)
• Allergen exposure routes:
- Inhaled, Ingested, Injected, Skin or mucous membrane
Assessment - ANSWER • What are signs of inflammation?
• How do these manifest in allergic reactions?
• Histamine is the major driver of these responses.
• Severe: Anaphylaxis, Angioedema, Asthma (varied severity) • Less severe: Hay fever"
AKA allergic rhinitis
