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INTRODUCTION TO GENERIC ANALYSIS
PRACTICE GUIDE |ACTUAL EXAM
QUESTIONS WITH CORRECT ANSWERS
|LATEST 2025
You cross a monohybrid with itself. What is the phenotype ratio that you expect to see? -
CORRECT 3:1
Question.
You have a gene of which only two alleles exist, and you perform a monohybrid cross. How
many different genotypes might be observed in the progeny? - CORRECT 3
Question.
"dumpy" is a commonly used mutant phenotype in the nematode worm C. elegans. You
cross a dumpy individual with a wildtype individual. In the F1 generation you observe 710
wildtype individuals. You preform the monohybrid cross and observe a 3:1 ratio of wildtype
to dumpy. Which allele is dominant? - CORRECT wildtype
Question.
1. A dominant gene b+ is responsible for the wildtype body color of Drosophila; its recessive
allele b produces black body color. A testcross of a heterozygous b+/b female by a black b/b
male gave 52 black and 58 wildtype progeny. If a black female from this progeny were
crossed with a wildtype brother, what phenotypic ratio would be expected in their offspring?
- CORRECT 50% will be wildtype and 50% will be black
Question.
A Female drosophila with a mutant phenotype a is crossed to a male who has the wildtype
phenotype +. In the results of the F1 generation all females are wildtype and all males have
the mutant phenotype. Based on these results, we can conclude that the mode of
inheritance of the mutant phenotype is? - CORRECT x linked recessive
Question.
1. A mutation occurs in a germ cell of a pure breeding wildtype male mouse prior to DNA
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replication. The mutation is not corrected, and the cell undergoes DNA replication and a
normal meiosis producing four gametes. How many of these gametes will carry the
mutation? - CORRECT 2
Question.
A phenotypically normal female is heterozygous for the X linked recessive Mendelian allele
that causes Red/Green colorblindness. She has the children with a male with normal vision.
How many of her male offspring are expected to have the red/green colorblindness? -
CORRECT 50%
Question.
A phenotypically normal woman is heterozygous for the X linked recessive Mendelian allele
causing Red/Green colorblindness. She has children with a male who has normal vision.
What percentage of her eggs will carry the X linked recessive allele that causes color
blindness? - CORRECT 50%
Question.
A phenotypically normal woman does not carry the gene for the X linked Recessive
mendelian allele causing red/green color blindness. She has children with a male who is
colorblind. What percentage of her female progeny will carry the allele that causes
colorblindness? - CORRECT 100%
Question.
A phenotypically colorblind women is homozygous for the X linked recessive mendelian
allele causing red/green colorblindness. She has children with a male who is not colorblind.
What percentage of her female progeny will carry the allele that causes red/green
colorblindness? - CORRECT 0%
Question.
1. A phenotypically colorblind women is homozygous for the X linked recessive mendelian
allele causing red/green colorblindness. She has children with a male who is not colorblind.
What percentage of her male progeny will be colorblind? - CORRECT 100%
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Question.
A sample of normal double stranded DNA was found to have a guanine content of 18%.
What is the expected portion of cytosine? - CORRECT 18%
Question.
A sample of normal double stranded DNA was found to have a guanine content of 18%.
What is the expected portion of adenine? - CORRECT 32%
Question.
1. A plant is heterozygous, and you cross it with a homozygous recessive. How many
different gamete genotypes can it theoretically produce in respect to this gene? -
CORRECT 2
Question.
1. A You cross a monohybrid with itself. What is the genotypic ratio that you would expect to
observe? - CORRECT 1:2:1
Question.
A wildtype strain of haploid yeast is crossed to a mutant strain with phenotype d. What
phenotypic ratios will be observed in the progeny? - CORRECT 50% wildtype 50%
mutant
Question.
1. An orange flower is crossed with a wildtype purple flower. All the F1 flowers are purple,
and of 1760 F2 flowers are sampled, 1320 are purple and 440 are orange. What is the
phenotypic ratio of the F2 progeny? - CORRECT 3:1
Question.
If a plant genotype A/a is selfed, and numerus offspring are scored, what proportion of the
progeny is expected to have homozygous genotypes? - CORRECT 50%
Question.
1. If you have a mendelian gene inheritance, and yellow pea color is dominant, Y, to green
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pea color y. You have a yellow pea of unknown genotype. You performed a testcross and find
that all the progeny have yellow peas. What is the genotype of the original yellow pea. -
CORRECT YY
Question.
In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence
in the other strand must be? - CORRECT 3'-TACG-5'
Question.
In pet rabbits, brown coat color is recessive to a black coat. A black female rabbit gives birth
to four black coated and three brown coated baby rabbits. What can be deduced about the
genotype of the baby rabbits' father? - CORRECT He could be heterozygous brown
black or homozygous brown
Question.
The central dogma describes... - CORRECT The flow of genetic information within cells
from DNA to RNA to Protein
Question.
1. The Early mid 1900s was an important period for genetics due to which of the following
major events?
a. Walter Dutton and Theodore Boveri hypothesizing that chromosomes are the hereditary
elements
b. Watson and Crick solving the structure of DNA
c. The rediscovery of Gregor Mendel's scientific findings
d. The rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
Boveri hypothesizing that chromosomes are the hereditary elements
e. All of the above - CORRECT E all of the above
Question.
1. The Wildtype eye color in the fruit fly Drosphila is dark red, and the mutant eye color is
white. If this allele is an X linked Mendelian Allele and you cross a dominant red eyed male
INTRODUCTION TO GENERIC ANALYSIS
PRACTICE GUIDE |ACTUAL EXAM
QUESTIONS WITH CORRECT ANSWERS
|LATEST 2025
You cross a monohybrid with itself. What is the phenotype ratio that you expect to see? -
CORRECT 3:1
Question.
You have a gene of which only two alleles exist, and you perform a monohybrid cross. How
many different genotypes might be observed in the progeny? - CORRECT 3
Question.
"dumpy" is a commonly used mutant phenotype in the nematode worm C. elegans. You
cross a dumpy individual with a wildtype individual. In the F1 generation you observe 710
wildtype individuals. You preform the monohybrid cross and observe a 3:1 ratio of wildtype
to dumpy. Which allele is dominant? - CORRECT wildtype
Question.
1. A dominant gene b+ is responsible for the wildtype body color of Drosophila; its recessive
allele b produces black body color. A testcross of a heterozygous b+/b female by a black b/b
male gave 52 black and 58 wildtype progeny. If a black female from this progeny were
crossed with a wildtype brother, what phenotypic ratio would be expected in their offspring?
- CORRECT 50% will be wildtype and 50% will be black
Question.
A Female drosophila with a mutant phenotype a is crossed to a male who has the wildtype
phenotype +. In the results of the F1 generation all females are wildtype and all males have
the mutant phenotype. Based on these results, we can conclude that the mode of
inheritance of the mutant phenotype is? - CORRECT x linked recessive
Question.
1. A mutation occurs in a germ cell of a pure breeding wildtype male mouse prior to DNA
, Page |2
replication. The mutation is not corrected, and the cell undergoes DNA replication and a
normal meiosis producing four gametes. How many of these gametes will carry the
mutation? - CORRECT 2
Question.
A phenotypically normal female is heterozygous for the X linked recessive Mendelian allele
that causes Red/Green colorblindness. She has the children with a male with normal vision.
How many of her male offspring are expected to have the red/green colorblindness? -
CORRECT 50%
Question.
A phenotypically normal woman is heterozygous for the X linked recessive Mendelian allele
causing Red/Green colorblindness. She has children with a male who has normal vision.
What percentage of her eggs will carry the X linked recessive allele that causes color
blindness? - CORRECT 50%
Question.
A phenotypically normal woman does not carry the gene for the X linked Recessive
mendelian allele causing red/green color blindness. She has children with a male who is
colorblind. What percentage of her female progeny will carry the allele that causes
colorblindness? - CORRECT 100%
Question.
A phenotypically colorblind women is homozygous for the X linked recessive mendelian
allele causing red/green colorblindness. She has children with a male who is not colorblind.
What percentage of her female progeny will carry the allele that causes red/green
colorblindness? - CORRECT 0%
Question.
1. A phenotypically colorblind women is homozygous for the X linked recessive mendelian
allele causing red/green colorblindness. She has children with a male who is not colorblind.
What percentage of her male progeny will be colorblind? - CORRECT 100%
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Question.
A sample of normal double stranded DNA was found to have a guanine content of 18%.
What is the expected portion of cytosine? - CORRECT 18%
Question.
A sample of normal double stranded DNA was found to have a guanine content of 18%.
What is the expected portion of adenine? - CORRECT 32%
Question.
1. A plant is heterozygous, and you cross it with a homozygous recessive. How many
different gamete genotypes can it theoretically produce in respect to this gene? -
CORRECT 2
Question.
1. A You cross a monohybrid with itself. What is the genotypic ratio that you would expect to
observe? - CORRECT 1:2:1
Question.
A wildtype strain of haploid yeast is crossed to a mutant strain with phenotype d. What
phenotypic ratios will be observed in the progeny? - CORRECT 50% wildtype 50%
mutant
Question.
1. An orange flower is crossed with a wildtype purple flower. All the F1 flowers are purple,
and of 1760 F2 flowers are sampled, 1320 are purple and 440 are orange. What is the
phenotypic ratio of the F2 progeny? - CORRECT 3:1
Question.
If a plant genotype A/a is selfed, and numerus offspring are scored, what proportion of the
progeny is expected to have homozygous genotypes? - CORRECT 50%
Question.
1. If you have a mendelian gene inheritance, and yellow pea color is dominant, Y, to green
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pea color y. You have a yellow pea of unknown genotype. You performed a testcross and find
that all the progeny have yellow peas. What is the genotype of the original yellow pea. -
CORRECT YY
Question.
In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence
in the other strand must be? - CORRECT 3'-TACG-5'
Question.
In pet rabbits, brown coat color is recessive to a black coat. A black female rabbit gives birth
to four black coated and three brown coated baby rabbits. What can be deduced about the
genotype of the baby rabbits' father? - CORRECT He could be heterozygous brown
black or homozygous brown
Question.
The central dogma describes... - CORRECT The flow of genetic information within cells
from DNA to RNA to Protein
Question.
1. The Early mid 1900s was an important period for genetics due to which of the following
major events?
a. Walter Dutton and Theodore Boveri hypothesizing that chromosomes are the hereditary
elements
b. Watson and Crick solving the structure of DNA
c. The rediscovery of Gregor Mendel's scientific findings
d. The rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
Boveri hypothesizing that chromosomes are the hereditary elements
e. All of the above - CORRECT E all of the above
Question.
1. The Wildtype eye color in the fruit fly Drosphila is dark red, and the mutant eye color is
white. If this allele is an X linked Mendelian Allele and you cross a dominant red eyed male
